Possible Involvement of Liver Resident Macrophages (Kupffer Cells) in the Pathogenesis of Both Intrahepatic and Extrahepatic Inflammation

Canadian Journal of Gastroenterology and Hepatology

Volumn 2017, Issue , 2017, Pages

  Kakinuma, Yuki ^a   Kimura, Takuya ^a   Watanabe, Yoshifumi ^a  

^a MUSASHINO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; TUMOR NECROSIS FACTOR; COLLAGEN; CONCANAVALIN A; DEXTRAN SULFATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIC SCORE; ARTHRITIS; ARTICLE; CELL PROLIFERATION ASSAY; COLITIS; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DETERMINATION; EXTRAHEPATIC BILE DUCT; FEMALE; FLOW CYTOMETRY; HEPATITIS; INFLAMMATION; INTRAHEPATIC CHOLESTASIS; JOINT SWELLING; KUPFFER CELL; LIVER INJURY; MACROPHAGE; MOUSE; MTT ASSAY; NONHUMAN; PATHOLOGICAL ANATOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM; SPLEEN CELL; WEIGHT REDUCTION; ACUTE DISEASE; ANIMAL; C57BL MOUSE; CHRONIC DISEASE; DBA MOUSE; DISEASE MODEL; EXPERIMENTAL ARTHRITIS; INSTITUTE FOR CANCER RESEARCH MOUSE; LIVER; METABOLISM; PATHOLOGY;

ACUTE DISEASE; ANIMALS; ARTHRITIS, EXPERIMENTAL; CHRONIC DISEASE; COLITIS; COLLAGEN; CONCANAVALIN A; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; FEMALE; INFLAMMATION; KUPFFER CELLS; LIVER; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, INBRED ICR;

EID: 85027231800     PISSN: 22912789     EISSN: 22912797     Source Type: Journal    
DOI: 10.1155/2017/2896809     Document Type: Article

References (51)

1. G. Biozzi and C. Stiffel, "The physiopathology of the reticuloendothelial cells of the liver and spleen," Progress in Liver Diseases, vol. 2, p. 166, 1965.
2. R. S. Haltiwanger, M. A. Lehrman, A. E. Eckhardt, and R. L. Hill, "The distribution and localization of the fucose-binding lectin in rat tissues and the identification of a high affinity form of the mannose/N-acetylglucosamine-binding lectin in rat liver," Journal of Biological Chemistry, vol. 261, no. 16, pp. 7433-7439, 1986.
3. K. Y. Helmy, K. J. Katschke Jr., N. N. Gorgani et al., "CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens," Cell, vol. 124, no. 5, pp. 915-927, 2006.
4. K. Jung, M. Kang, C. Park et al., "Protective role of V-set and immunoglobulin domain-containing 4 expressed on kupffer cells during immune-mediated liver injury by inducing tolerance of liver T- and natural killer T-cells," Hepatology, vol. 56, no. 5, pp. 1838-1848, 2012.
5. Y. Kimura, A. Inoue, S. Hangai et al., "The innate immune receptor Dectin-2 mediates the phagocytosis of cancer cells by Kupffer cells for the suppression of livermetastasis," Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 49, pp. 14097-14102, 2016.
6. D. Movita, K. Kreefft, P. Biesta et al., "Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages," Journal of Leukocyte Biology, vol. 92, no. 4, pp. 723-733, 2012.
7. T. Okada, A. Kimura, K. Kanki et al., "Liver resident macrophages (kupffer cells) share several functional antigens in common with endothelial cells," Scandinavian Journal of Immunology, vol. 83, no. 2, pp. 139-150, 2016.
8. N. Duarte, I. C. Coelho, R. S. Patarrão, J. I. Almeida, C. Penha-Gonccedil;alves, and M. P. Macedo, "How inflammation impinges on NAFLD: a role for Kupffer cells," BioMed Research International, vol. 2015, Article ID984578, 11 pages, 2015.
9. M. Hatano, S. Sasaki, S. Ohata et al., "Effects of Kupffer cell-depletion on Concanavalin A-induced hepatitis," Cellular Immunology, vol. 251, no. 1, pp. 25-30, 2008.
10. F. Heymann, J. Peusquens, I. Ludwig-Portugall et al., "Liver inflammation abrogates immunological tolerance induced by kupffer cells," Hepatology, vol. 62, no. 1, pp. 279-291, 2015.
11. H. Nakashima, M. Kinoshita, M. Nakashima et al., "Superoxide produced byKupffer cells is an essential effector in concanavalin A-induced hepatitis in mice," Hepatology, vol. 48, no. 6, pp. 1979-1988, 2008.
12. J. Schümann, D. Wolf, A. Pahl et al., "Importance ofKupffer cells for T-cell-dependent liver injury in mice, "TheAmerican Journal of Pathology, vol. 157, no. 5, pp. 1671-1683, 2000.
13. Y. Tian, W. Jochum, P. Georgiev, W. Moritz, R. Graf, and P.- A. Clavien, "Kupffer cell-dependent TNF-α signaling mediates injury in the arterialized small-for-size liver transplantation in the mouse," Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 12, pp. 4598-4603, 2006.
14. H. Tsutsui and S. Nishiguchi, "Importance of kupffer cells in the development of acute liver injuries in mice," International Journal of Molecular Sciences, vol. 15, no. 5, pp. 7711-7730, 2014.
15. N. Van Rooijen and A. Sanders, "Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications," Journal of Immunological Methods, vol. 174, no. 1-2, pp. 83-93, 1994.
16. I. Shibuya, T. Akaike, and Y. Watanabe, "Design of a temporally and spatially controlled drug delivery system for the treatment of liver diseases in mice," Hepatology, vol. 32, no. 6, pp. 1300- 1308, 2000.
17. H. Sann, J. V. Erichsen, M. Hessmann, A. Pahl, and A. Hoffmeyer, "Efficacy of drugs used in the treatment of IBD and combinations thereof in acute DSS-induced colitis in mice," Life Sciences, vol. 92, no. 12, pp. 708-718, 2013.
18. D. D. Brand, K. A. Latham, and E. F. Rosloniec, "Collageninduced arthritis," Nature Protocols, vol. 2, no. 5, pp. 1269-1275, 2007.
19. N. Van Rooijen and A. Sanders, "Kupffer cell depletion by liposome-delivered drugs: comparative activity of intracellular clodronate, propamidine, and ethylenediaminetetraacetic acid," Hepatology, vol. 23, no. 5, pp. 1239-1243, 1996.
20. Y. Ishijima, T. Kawamura, A. Kimura et al., "Toll-like receptor 4-dependent adjuvant activity of Kakkon-to extract exists in the high molecular weight polysaccharide fraction," International Journal of Immunopathology and Pharmacology, vol. 24, no. 1, pp. 43-54, 2011.
21. T. Mosmann, "Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays," Journal of Immunological Methods, vol. 65, no. 1-2, pp. 55-63, 1983.
22. I. Ajioka, T. Akaike, and Y. Watanabe, "Expression of vascular endothelial growth factor promotes colonization, vascularization, and growth of transplanted hepatic tissues in the mouse," Hepatology, vol. 29, no. 2, pp. 396-402, 1999.
23. I. Koboziev, F. Karlsson, S. Zhang, and M. B. Grisham, "Pharmacological intervention studies using mouse models of the inflammatory bowel diseases: Translating preclinical data into new drug therapies," Inflammatory Bowel Diseases, vol. 17, no. 5, pp. 1229-1245, 2011.
24. Y. Yan, V. Kolachala, G. Dalmasso et al., "Temporal and spatial analysis of clinical andmolecular parameters in dextran sodium sulfate induced colitis," PLoS ONE, vol. 4, no. 6, Article ID e6073, 2009.
25. R.W. Kinne, C. B. Schmidt-Weber, R. Hoppe et al., "Long-term amelioration of rat adjuvant arthritis following systemic elimination of macrophages by clodronate-containing liposomes," Arthritis & Rheumatism, vol. 38, no. 12, pp. 1777-1790, 1995.
26. P. J. Richards, A. S. Williams, R. M. Goodfellow, and B. D. Williams, "Liposomal clodronate eliminates synovial macrophages, reduces inflammation and ameliorates joint destruction in antigen-induced arthritis," Rheumatology, vol. 38, no. 9, pp. 818-825, 1999.
27. P. Barrera, A. Blom, P. L. Van Lent et al., "Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis," Arthritis & Rheumatism, vol. 43, no. 9, pp. 1951-1959.
28. P. L. E. M. Van Lent, A. E. M. Holthuysen, N. Van Rooijen, L. B. A. Van De Putte, and W. B. Van Den Berg, "Local removal of phagocytic synovial lining cells by clodronate-liposomes decreases cartilage destruction during collagen type II arthritis," Annals of the Rheumatic Diseases, vol. 57, no. 7, pp. 408-413, 1998.
29. K. Greish, "Enhanced permeability and retention (EPR) effect for anticancer nanomedicine drug targeting," Methods in Molecular Biology, vol. 624, pp. 25-37, 2010.
30. H. F. Dvorak, J. A. Nagy, J. T. Dvorak, and A. M. Dvorak, "Identification and characterization of the blood vessels of solid tumors that are leaky to circulatingmacromolecules," American Journal of Pathology, vol. 133, no. 1, pp. 95-109, 1988.
31. M. Ikarashi, H. Nakashima, M. Kinoshita et al., "Distinct development and functions of resident and recruited liver Kupffer cells/macrophages," Journal of Leukocyte Biology, vol. 94, no. 6, pp. 1325-1336, 2013.
32. I. Klein, J. C. Cornejo, N. K. Polakos et al., "Kupffer cell heterogeneity: functional properties of bone marrow-derived and sessile hepatic macrophages," Blood, vol. 110, no. 12, pp. 4077- 4085, 2007.
33. M. Bilzer, F. Roggel, and A. L. Gerbes, "Role of Kupffer cells in host defense and liver disease," Liver International, vol. 26, no. 10, pp. 1175-1186, 2006.
34. A. Erhardt, M. Biburger, T. Papadopoulos, and G. Tiegs, "IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice," Hepatology, vol. 45, no. 2, pp. 475-485, 2007.
35. S. Gehring, E. M. Dickson, M. E. SanMartin et al., "Kupffer cells abrogate cholestatic liver injury in mice," Gastroenterology, vol. 130, no. 3, pp. 810-822, 2006.
36. J. Wan, M. Benkdane, F. Teixeira-Clerc et al., "M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease," Hepatology, vol. 59, no. 1, pp. 130-142, 2014.
37. Q. You, L. Cheng, R. M. Kedl, and C. Ju, "Mechanism of T cell tolerance induction by murine hepatic Kupffer cells," Hepatology, vol. 48, no. 3, pp. 978-990, 2008.
38. D. Zuo, X. Yu, C. Guo et al., "Scavenger receptor a restrains T-cell activation and protects against concanavalin A-induced hepatic injury," Hepatology, vol. 57, no. 1, pp. 228-238, 2013.
39. M. Tanaka, T. Nagai, Y. Tsuneyoshi et al., "Expansion of a unique macrophage subset in rheumatoid arthritis synovial lining layer," Clinical and Experimental Immunology, vol. 154, no. 1, pp. 38-47, 2008.
40. F. Zheng, S. Put, L. Bouwens et al., "Molecular imaging with macrophage crig-targeting nanobodies for early and preclinical diagnosis in a mouse model of rheumatoid arthritis," Journal of Nuclear Medicine, vol. 55, no. 5, pp. 824-829, 2014.
41. J. D. Milner, T. Orekov, J. M. Ward et al., "Sustained IL-4 exposure leads to a novel pathway for hemophagocytosis, inflammation, and tissue macrophage accumulation," Blood, vol. 116, no. 14, pp. 2476-2483, 2010.
42. C. L. Elsegood, C.W. Chan, M. A. Degli-Esposti et al., "Kupffer cell-monocyte communication is essential for initiatingmurine liver progenitor cell-mediated liver regeneration," Hepatology, vol. 62, no. 4, pp. 1272-1284, 2015.
43. K. Fujiu, M. Shibata, Y. Nakayama et al., "A heart-brain-kidney network controls adaptation to cardiac stress through tissue macrophage activation," Nature Medicine, vol. 23, no. 5, pp. 611- 622, 2017.
44. M. Noack and P. Miossec, "Th17 and regulatory T cell balance in autoimmune and inflammatory diseases," Autoimmunity Reviews, vol. 13, no. 6, pp. 668-677, 2014.
45. N. Komatsu, K. Okamoto, S. Sawa et al., "Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis," Nature Medicine, vol. 20, no. 1, pp. 62-68, 2014.
46. E. Lubberts, M. I. Koenders, and W. B. vandenBerg, "The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models," Arthritis Research and Therapy, vol. 7, no. 1, pp. 29-37, 2005.
47. S. Nakae, A. Nambu, K. Sudo, and Y. Iwakura, "Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice," Journal of Immunology, vol. 171, no. 11, pp. 6173- 6177, 2003.
48. P. J. De Bleser, T. Niki, V. Rogiers, and A. Geerts, "Transforming growth factor-β gene expression in normal and fibrotic rat liver," Journal of Hepatology, vol. 26, no. 4, pp. 886-893, 1997.
49. S. Roth, W. Gong, and A. M. Gressner, "Expression of different isoforms of TGF-β and the latent TGF-β binding protein (LTBP) by rat Kupffer cells," Journal of Hepatology, vol. 29, no. 6, pp. 915-922, 1998.
50. M. Sasai, Y. Saeki, S. Ohshima et al., "Delayed onset and reduced severity of collagen-induced arthritis in interleukin-6-deficient mice," Arthritis and Rheumatism, vol. 42, no. 8, pp. 1635-1643, 1999.
51. C. Du, P. Wang, Y. Yu, F. Chen, J. Liu, and Y. Li, "Gadolinium chloride improves the course of TNBS and DSS-induced colitis through protecting against colonicmucosal inflammation," Scientific Reports, vol. 4, article no. 6096, 2014.