Molecular imaging with macrophage crig-targeting nanobodies for early and preclinical diagnosis in a mouse model of rheumatoid arthritis

Journal of Nuclear Medicine

Volumn 55, Issue 5, 2014, Pages 824-829

  Zheng, Fang ^a,b   Put, Stéphanie ^c   Bouwens, Luc ^a   Lahoutte, Tony ^a   Matthys, Patrick ^c   Muyldermans, Serge ^a   De Baetselier, Patrick ^a,b   Devoogdt, Nick ^a   Raes, Geert ^a,b   Schoonooghe, Steve ^a,b  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Collagen induced arthritis (CIA); Complement receptor of the Ig superfamily (CRIg; Macrophage; Nanobody; Or Z39Ig); SPECT CT; VSIG4

Indexed keywords

BIOLOGICAL MARKER; COMPLEMENT RECEPTOR OF THE IMMUNOGLOBULIN SUPERFAMILY; MESSENGER RNA; NANOBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CRIG GENE; DISEASE SEVERITY; EARLY DIAGNOSIS; FLOW CYTOMETRY; GENE EXPRESSION; KNEE ARTHRITIS; MACROPHAGE; MALE; MARKER GENE; MOLECULAR IMAGING; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; RHEUMATOID ARTHRITIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; UPREGULATION;

COLLAGEN-INDUCED ARTHRITIS (CIA); COMPLEMENT RECEPTOR OF THE IG SUPERFAMILY (CRIG, VSIG4, OR Z39IG); MACROPHAGE; NANOBODY; SPECT/ΜCT;

ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MOLECULAR IMAGING; RADIOPHARMACEUTICALS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, COMPLEMENT; RNA, MESSENGER; SINGLE-DOMAIN ANTIBODIES; SYNOVIAL MEMBRANE; TECHNETIUM; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; X-RAY MICROTOMOGRAPHY;

EID: 84900997693     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.113.130617     Document Type: Article

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