The innate immune receptor Dectin-2 mediates the phagocytosis of cancer cells by Kupffer cells for the suppression of liver metastasis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 49, 2016, Pages 14097-14102

  Kimura, Yoshitaka ^a   Inoue, Asuka ^a,b   Hangai, Sho ^a,c   Saijo, Shinobu ^d   Negishi, Hideo ^a   Nishio, Junko ^a   Yamasaki, Sho ^e   Iwakura, Yoichiro ^f   Yanai, Hideyuki ^a,c   Taniguchi, Tadatsugu ^a,c  

^a INSTITUTE OF INDUSTRIAL SCIENCE   (Japan)

^b Sanofi KK   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d CHIBA UNIVERSITY   (Japan)

^e KYUSHU UNIVERSITY   (Japan)

^f TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

C type lectin receptor; Dectin 2; Kupffer cell; Liver metastasis; Phagocytosis

Indexed keywords

DECTIN 2; CLEC4D PROTEIN, MOUSE; DECTIN-2, MOUSE; IMMUNOGLOBULIN RECEPTOR; LECTIN;

ANIMAL CELL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CANCER GROWTH; INNATE IMMUNITY; KUPFFER CELL; LIVER METASTASIS; LUNG ALVEOLUS MACROPHAGE; LUNG METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN FUNCTION; ANIMAL; C57BL MOUSE; EXPERIMENTAL LIVER NEOPLASM; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; METASTASIS; PHYSIOLOGY; SECONDARY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; HUMANS; KUPFFER CELLS; LECTINS, C-TYPE; LIVER NEOPLASMS, EXPERIMENTAL; MICE, INBRED C57BL; NEOPLASM METASTASIS; PHAGOCYTOSIS; RECEPTORS, IMMUNOLOGIC;

EID: 85002607140     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1617903113     Document Type: Article

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