Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy

Nucleic Acids Research

Volumn 45, Issue 13, 2017, Pages 8091-8104

  Blocquel, David ^a   Li, Sheng ^b   Wei, Na ^a   Daub, Herwin ^c   Sajish, Mathew ^a   Erfurth, Maria Luise ^d   Kooi, Grace ^a   Zhou, Jiadong ^a   Bai, Ge ^a   Schimmel, Paul ^a   Jordanova, Albena ^d   Yang, Xiang Lei ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c DYNAMIC BIOSENSORS GMBH   (Germany)

^d UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

TYROSINE TRANSFER RNA LIGASE; MUTANT PROTEIN; PROTEIN BINDING; RECOMBINANT PROTEIN; REPRESSOR PROTEIN; TRIM28 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; HEREDITARY MOTOR SENSORY NEUROPATHY; MUTATION; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; AMINO ACID SUBSTITUTION; CHEMISTRY; DEUTERIUM HYDROGEN EXCHANGE; ENZYME STABILITY; ENZYMOLOGY; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR MODEL; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; SMALL ANGLE SCATTERING; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

AMINO ACID SUBSTITUTION; CHARCOT-MARIE-TOOTH DISEASE; CRYSTALLOGRAPHY, X-RAY; DEUTERIUM EXCHANGE MEASUREMENT; ENZYME STABILITY; HUMANS; KINETICS; MODELS, MOLECULAR; MUTANT PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; SCATTERING, SMALL ANGLE; TYROSINE-TRNA LIGASE; X-RAY DIFFRACTION;

EID: 85026399899     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkx455     Document Type: Article

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