Minimizing back exchange in the hydrogen exchange-mass spectrometry experiment

Journal of the American Society for Mass Spectrometry

Volumn 23, Issue 12, 2012, Pages 2132-2139

  Walters, Benjamin T ^a,b   Ricciuti, Alec ^a,b   Mayne, Leland ^a   Englander, S Walter ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Amide hydrogen exchange; Back exchange; Deuterium recovery; HDX MS; HX MS; HXMS; Hydrogen deuterium exchange

Indexed keywords

AMIDE HYDROGENS; DEUTERIUM RECOVERY; HDX MS; HX MS; HYDROGEN/DEUTERIUM EXCHANGE;

AMINO ACIDS; DEUTERIUM; EXPERIMENTS; HYDROGEN; IONIC STRENGTH; MASS SPECTROMETRY; RECOVERY;

PEPTIDES;

AMINO ACID; DEUTERIUM; HYDROGEN; AMIDE; ESCHERICHIA COLI PROTEIN; MALE PROTEIN, E COLI; PEPTIDE; PERIPLASMIC BINDING PROTEIN;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEGRADATION; DESOLVATION TEMPERATURE; ELUTION; FLOW RATE; FRAGMENTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN EXCHANGE MASS SPECTROMETRY; IONIC STRENGTH; MASS SPECTROMETER; MASS SPECTROMETRY; PH; PROTEIN ANALYSIS; PROTEIN DEGRADATION; SEPARATION TECHNIQUE; TEMPERATURE; CHEMICAL STRUCTURE; CHEMISTRY; DEUTERIUM HYDROGEN EXCHANGE; ELECTROSPRAY MASS SPECTROMETRY; METHODOLOGY; OSMOLARITY; SIGNAL NOISE RATIO;

AMIDES; DEUTERIUM EXCHANGE MEASUREMENT; ESCHERICHIA COLI PROTEINS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; OSMOLAR CONCENTRATION; PEPTIDES; PERIPLASMIC BINDING PROTEINS; SIGNAL-TO-NOISE RATIO; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TEMPERATURE;

EID: 84868575176     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-012-0476-x     Document Type: Article

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