-
1
-
-
84872485255
-
The biochemistry of hematopoietic stem cell development
-
Kaimakis, P., Crisan, M. & Dzierzak, E. The biochemistry of hematopoietic stem cell development. Biochim. Biophys. Acta. 1830, 2395-2403 (2013).
-
(2013)
Biochim. Biophys. Acta.
, vol.1830
, pp. 2395-2403
-
-
Kaimakis, P.1
Crisan, M.2
Dzierzak, E.3
-
2
-
-
38349179230
-
Of lineage and legacy: The development of mammalian hematopoietic stem cells
-
Dzierzak, E. & Speck, N. A. Of lineage and legacy: the development of mammalian hematopoietic stem cells. Nat. Immunol. 9, 129-136 (2008).
-
(2008)
Nat. Immunol.
, vol.9
, pp. 129-136
-
-
Dzierzak, E.1
Speck, N.A.2
-
3
-
-
82755192925
-
Hemogenic endothelium: Origins, regulation, and implications for vascular biology
-
Zape, J. P. & Zovein, A. C. Hemogenic endothelium: origins, regulation, and implications for vascular biology. Semin. Cell Dev. Biol. 22, 1036-1047 (2011).
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 1036-1047
-
-
Zape, J.P.1
Zovein, A.C.2
-
4
-
-
77949895151
-
Haematopoietic stem cells derive directly from aortic endothelium during development
-
Bertrand, J. Y. et al. Haematopoietic stem cells derive directly from aortic endothelium during development. Nature 464, 108-111 (2010).
-
(2010)
Nature
, vol.464
, pp. 108-111
-
-
Bertrand, J.Y.1
-
5
-
-
60149102751
-
Continuous single-cell imaging of blood generation from haemogenic endothelium
-
Eilken, H. M., Nishikawa, S. & Schroeder, T. Continuous single-cell imaging of blood generation from haemogenic endothelium. Nature 457, 896-900 (2009).
-
(2009)
Nature
, vol.457
, pp. 896-900
-
-
Eilken, H.M.1
Nishikawa, S.2
Schroeder, T.3
-
6
-
-
77949903295
-
Blood stem cells emerge from aortic endothelium by a novel type of cell transition
-
Kissa, K. & Herbomel, P. Blood stem cells emerge from aortic endothelium by a novel type of cell transition. Nature 464, 112-115 (2010).
-
(2010)
Nature
, vol.464
, pp. 112-115
-
-
Kissa, K.1
Herbomel, P.2
-
7
-
-
77949911441
-
In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium
-
Boisset, J. C. et al. In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium. Nature 464, 116-120 (2010).
-
(2010)
Nature
, vol.464
, pp. 116-120
-
-
Boisset, J.C.1
-
8
-
-
33845448620
-
Tracing hematopoietic precursor migration to successive hematopoietic organs during zebrafish development
-
Murayama, E. et al. Tracing hematopoietic precursor migration to successive hematopoietic organs during zebrafish development. Immunity 25, 963-975 (2006).
-
(2006)
Immunity
, vol.25
, pp. 963-975
-
-
Murayama, E.1
-
9
-
-
84911935849
-
Proinflammatory signaling regulates hematopoietic stem cell emergence
-
Espin-Palazon, R. et al. Proinflammatory signaling regulates hematopoietic stem cell emergence. Cell 159, 1070-1085 (2014).
-
(2014)
Cell
, vol.159
, pp. 1070-1085
-
-
Espin-Palazon, R.1
-
10
-
-
84914164467
-
Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production
-
Li, Y. et al. Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production. Genes Dev. 28, 2597-2612 (2014).
-
(2014)
Genes Dev.
, vol.28
, pp. 2597-2612
-
-
Li, Y.1
-
11
-
-
84918509951
-
Interferon gamma signaling positively regulates hematopoietic stem cell emergence
-
Sawamiphak, S., Kontarakis, Z. & Stainier, D. Y. Interferon gamma signaling positively regulates hematopoietic stem cell emergence. Dev. Cell. 31, 640-653 (2014).
-
(2014)
Dev. Cell.
, vol.31
, pp. 640-653
-
-
Sawamiphak, S.1
Kontarakis, Z.2
Stainier, D.Y.3
-
12
-
-
84923314925
-
Inflammatory signaling regulates hematopoietic stem and progenitor cell emergence in vertebrates
-
He, Q. et al. Inflammatory signaling regulates hematopoietic stem and progenitor cell emergence in vertebrates. Blood 125, 1098-1106 (2015).
-
(2015)
Blood
, vol.125
, pp. 1098-1106
-
-
He, Q.1
-
13
-
-
84904985459
-
Regulation of microRNA biogenesis
-
Ha, M. & Kim, V. N. Regulation of microRNA biogenesis. Nat. Rev. Mol. Cell. Biol. 15, 509-524 (2014).
-
(2014)
Nat. Rev. Mol. Cell. Biol.
, vol.15
, pp. 509-524
-
-
Ha, M.1
Kim, V.N.2
-
14
-
-
84858379476
-
MicroRNAs in stress signaling and human disease
-
Mendell, J. T. & Olson, E. N. MicroRNAs in stress signaling and human disease. Cell 148, 1172-1187 (2012).
-
(2012)
Cell
, vol.148
, pp. 1172-1187
-
-
Mendell, J.T.1
Olson, E.N.2
-
15
-
-
84873661316
-
Functions of microRNAs in cardiovascular biology and disease
-
Hata, A. Functions of microRNAs in cardiovascular biology and disease. Annu. Rev. Physiol. 75, 69-93 (2013).
-
(2013)
Annu. Rev. Physiol.
, vol.75
, pp. 69-93
-
-
Hata, A.1
-
17
-
-
84924962270
-
Dysregulation of microRNA biogenesis and gene silencing in cancer
-
Hata, A. & Lieberman, J. Dysregulation of microRNA biogenesis and gene silencing in cancer. Sci. Signal. 8, re3 (2015).
-
(2015)
Sci. Signal.
, vol.8
, pp. re3
-
-
Hata, A.1
Lieberman, J.2
-
18
-
-
51049089025
-
The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease
-
Chong, M. M., Rasmussen, J. P., Rudensky, A. Y. & Littman, D. R. The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease. J. Exp. Med. 205, 2005-2017 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2005-2017
-
-
Chong, M.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
Littman, D.R.4
-
19
-
-
60149100010
-
Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter
-
Chen, M. J., Yokomizo, T., Zeigler, B. M., Dzierzak, E. & Speck, N. A. Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter. Nature 457, 887-891 (2009).
-
(2009)
Nature
, vol.457
, pp. 887-891
-
-
Chen, M.J.1
Yokomizo, T.2
Zeigler, B.M.3
Dzierzak, E.4
Speck, N.A.5
-
20
-
-
35548932872
-
A global doublefluorescent Cre reporter mouse
-
Muzumdar, M. D., Tasic, B., Miyamichi, K., Li, L. & Luo, L. A global doublefluorescent Cre reporter mouse. Genesis 45, 593-605 (2007).
-
(2007)
Genesis
, vol.45
, pp. 593-605
-
-
Muzumdar, M.D.1
Tasic, B.2
Miyamichi, K.3
Li, L.4
Luo, L.5
-
21
-
-
0026041826
-
Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule
-
Okada, S. et al. Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule. Blood 78, 1706-1712 (1991).
-
(1991)
Blood
, vol.78
, pp. 1706-1712
-
-
Okada, S.1
-
22
-
-
76749148097
-
Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation
-
Uhrin, P. et al. Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation. Blood 115, 3997-4005 (2010).
-
(2010)
Blood
, vol.115
, pp. 3997-4005
-
-
Uhrin, P.1
-
23
-
-
77952885004
-
Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling
-
Bertozzi, C. C. et al. Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling. Blood 116, 661-670 (2010).
-
(2010)
Blood
, vol.116
, pp. 661-670
-
-
Bertozzi, C.C.1
-
24
-
-
84867163397
-
Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning
-
Lim, K. C. et al. Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning. J. Clin. Invest. 122, 3705-3717 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3705-3717
-
-
Lim, K.C.1
-
25
-
-
34948856826
-
Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature
-
Srinivasan, R. S. et al. Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev. 21, 2422-2432 (2007).
-
(2007)
Genes Dev.
, vol.21
, pp. 2422-2432
-
-
Srinivasan, R.S.1
-
26
-
-
84929658396
-
Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription
-
Koh, F. M. et al. Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription. Proc. Natl Acad. Sci. USA 112, E1734-1743 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. E1734-E1743
-
-
Koh, F.M.1
-
27
-
-
84961291926
-
Progressive maturation toward hematopoietic stem cells in the mouse embryo aorta
-
Boisset, J. C. et al. Progressive maturation toward hematopoietic stem cells in the mouse embryo aorta. Blood 125, 465-469 (2015).
-
(2015)
Blood
, vol.125
, pp. 465-469
-
-
Boisset, J.C.1
-
28
-
-
78049326155
-
Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos
-
Yokomizo, T. & Dzierzak, E. Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development 137, 3651-3661 (2010).
-
(2010)
Development
, vol.137
, pp. 3651-3661
-
-
Yokomizo, T.1
Dzierzak, E.2
-
29
-
-
84965082769
-
Integrin alphaIIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta
-
Boisset, J. C., Clapes, T., Van Der Linden, R., Dzierzak, E. & Robin, C. Integrin alphaIIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta. Biol. Open 2, 525-532 (2013).
-
(2013)
Biol. Open
, vol.2
, pp. 525-532
-
-
Boisset, J.C.1
Clapes, T.2
Van Der Linden, R.3
Dzierzak, E.4
Robin, C.5
-
30
-
-
84883252822
-
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells
-
Tober, J., Yzaguirre, A. D., Piwarzyk, E. & Speck, N. A. Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells. Development 140, 3765-3776 (2013).
-
(2013)
Development
, vol.140
, pp. 3765-3776
-
-
Tober, J.1
Yzaguirre, A.D.2
Piwarzyk, E.3
Speck, N.A.4
-
31
-
-
79955961133
-
CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells
-
Robin, C., Ottersbach, K., Boisset, J. C., Oziemlak, A. & Dzierzak, E. CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells. Blood 117, 5088-5091 (2011).
-
(2011)
Blood
, vol.117
, pp. 5088-5091
-
-
Robin, C.1
Ottersbach, K.2
Boisset, J.C.3
Oziemlak, A.4
Dzierzak, E.5
-
32
-
-
84937866892
-
Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition
-
Lizama, C. O. et al. Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition. Nat. Commun. 6, 7739 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 7739
-
-
Lizama, C.O.1
-
33
-
-
54449087438
-
Analysis and manipulation of hematopoietic progenitor and stem cells from murine embryonic tissues
-
Chapter 2, Unit 2A 6
-
Medvinsky, A., Taoudi, S., Mendes, S. & Dzierzak, E. Analysis and manipulation of hematopoietic progenitor and stem cells from murine embryonic tissues. Curr. Protoc. Stem Cell Biol. Chapter 2, Unit 2A 6 (2008).
-
(2008)
Curr. Protoc. Stem Cell Biol.
-
-
Medvinsky, A.1
Taoudi, S.2
Mendes, S.3
Dzierzak, E.4
-
34
-
-
65749096452
-
The OP9-DL1 system: Generation of Tlymphocytes from embryonic or hematopoietic stem cells in vitro
-
Holmes, R. & Zuniga-Pflucker, J. C. The OP9-DL1 system: generation of Tlymphocytes from embryonic or hematopoietic stem cells in vitro. Cold Spring Harb. Protoc. 2009, pdb prot5156 (2009).
-
(2009)
Cold Spring Harb. Protoc. 2009, Pdb prot5156
-
-
Holmes, R.1
Zuniga-Pflucker, J.C.2
-
35
-
-
84899128804
-
Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation
-
Lan, Y. et al. Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation. Blood 123, 2161-2171 (2014).
-
(2014)
Blood
, vol.123
, pp. 2161-2171
-
-
Lan, Y.1
-
36
-
-
33744483364
-
Pituitary-specific Gata2 knockout: Effects on gonadotrope and thyrotrope function
-
Charles, M. A. et al. Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function. Mol. Endocrinol. 20, 1366-1377 (2006).
-
(2006)
Mol. Endocrinol.
, vol.20
, pp. 1366-1377
-
-
Charles, M.A.1
-
37
-
-
0030407667
-
Function of calcium-independent phospholipase A2 in arachidonic acid metabolism in P388D1 macrophages
-
Balsinde, J. & Dennis, E. A. Function of calcium-independent phospholipase A2 in arachidonic acid metabolism in P388D1 macrophages. Adv. Exp. Med. Biol. 407, 99-103 (1997).
-
(1997)
Adv. Exp. Med. Biol.
, vol.407
, pp. 99-103
-
-
Balsinde, J.1
Dennis, E.A.2
-
38
-
-
77952312969
-
Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis
-
Radmark, O. & Samuelsson, B. Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis. Biochem. Biophys. Res. Commun. 396, 105-110 (2010).
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.396
, pp. 105-110
-
-
Radmark, O.1
Samuelsson, B.2
-
39
-
-
84901609808
-
Leukotrienes in pulmonary arterial hypertension
-
Tian, W. et al. Leukotrienes in pulmonary arterial hypertension. Immunol. Res. 58, 387-393 (2014).
-
(2014)
Immunol. Res.
, vol.58
, pp. 387-393
-
-
Tian, W.1
-
40
-
-
0025647031
-
The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air
-
Israel, E. et al. The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air. N. Engl. J. Med. 323, 1740-1744 (1990).
-
(1990)
N. Engl. J. Med.
, vol.323
, pp. 1740-1744
-
-
Israel, E.1
-
41
-
-
0026332275
-
Pharmacokinetics, safety, and ability to diminish leukotriene synthesis by zileuton, an inhibitor of 5-lipoxygenase
-
Rubin, P. et al. Pharmacokinetics, safety, and ability to diminish leukotriene synthesis by zileuton, an inhibitor of 5-lipoxygenase. Agents Actions Suppl. 35, 103-116 (1991).
-
(1991)
Agents Actions Suppl.
, vol.35
, pp. 103-116
-
-
Rubin, P.1
-
42
-
-
0026517149
-
The discovery and development of zileuton: An orally active 5-lipoxygenase inhibitor
-
Bell, R. L. et al. The discovery and development of zileuton: an orally active 5-lipoxygenase inhibitor. Int. J. Immunopharmacol. 14, 505-510 (1992).
-
(1992)
Int. J. Immunopharmacol.
, vol.14
, pp. 505-510
-
-
Bell, R.L.1
-
43
-
-
0031017337
-
Arachidonic acid metabolites: Mediators of inflammation in asthma
-
Wenzel, S. E. Arachidonic acid metabolites: mediators of inflammation in asthma. Pharmacotherapy 17, 3S-12S (1997).
-
(1997)
Pharmacotherapy
, vol.17
, pp. 3S-12S
-
-
Wenzel, S.E.1
-
44
-
-
84937512929
-
The role of leukotrienes in allergic diseases
-
Liu, M. & Yokomizo, T. The role of leukotrienes in allergic diseases. Allergol. Int. 64, 17-26 (2015).
-
(2015)
Allergol. Int.
, vol.64
, pp. 17-26
-
-
Liu, M.1
Yokomizo, T.2
-
45
-
-
84947492704
-
Leukotriene B4 activates pulmonary artery adventitial fibroblasts in pulmonary hypertension
-
Qian, J. et al. Leukotriene B4 activates pulmonary artery adventitial fibroblasts in pulmonary hypertension. Hypertension 66, 1227-1239 (2015).
-
(2015)
Hypertension
, vol.66
, pp. 1227-1239
-
-
Qian, J.1
-
46
-
-
84937715035
-
MicroRNA-9 regulates the differentiation and function of myeloid-derived suppressor cells via targeting Runx1
-
Tian, J. et al. MicroRNA-9 regulates the differentiation and function of myeloid-derived suppressor cells via targeting Runx1. J. Immunol. 195, 1301-1311 (2015).
-
(2015)
J. Immunol.
, vol.195
, pp. 1301-1311
-
-
Tian, J.1
-
47
-
-
84959431492
-
Adhesion protein networks reveal functions proximal and distal to cell-matrix contacts
-
Byron, A. & Frame, M. C. Adhesion protein networks reveal functions proximal and distal to cell-matrix contacts. Curr. Opin. Cell Biol. 39, 93-100 (2016).
-
(2016)
Curr. Opin. Cell Biol.
, vol.39
, pp. 93-100
-
-
Byron, A.1
Frame, M.C.2
-
48
-
-
33947236925
-
Alpha4 and beta2 integrins have nonredundant roles for asthma development, but for optimal allergen sensitization only alpha4 is critical
-
Banerjee, E. R., Jiang, Y., Henderson, W. R. Jr., Scott, L. M. & Papayannopoulou, T. Alpha4 and beta2 integrins have nonredundant roles for asthma development, but for optimal allergen sensitization only alpha4 is critical. Exp. Hematol. 35, 605-617 (2007).
-
(2007)
Exp. Hematol.
, vol.35
, pp. 605-617
-
-
Banerjee, E.R.1
Jiang, Y.2
Henderson, W.R.3
Scott, L.M.4
Papayannopoulou, T.5
-
49
-
-
84922479718
-
MicroRNAs in hematopoiesis
-
Lazare, S. S., Wojtowicz, E. E., Bystrykh, L. V. & de Haan, G. microRNAs in hematopoiesis. Exp. Cell Res. 329, 234-238 (2014).
-
(2014)
Exp. Cell Res.
, vol.329
, pp. 234-238
-
-
Lazare, S.S.1
Wojtowicz, E.E.2
Bystrykh, L.V.3
De Haan, G.4
-
50
-
-
77950862042
-
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
-
Raaijmakers, M. H. et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature 464, 852-857 (2010).
-
(2010)
Nature
, vol.464
, pp. 852-857
-
-
Raaijmakers, M.H.1
-
51
-
-
84864744041
-
Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients
-
Santamaria, C. et al. Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients. Haematologica 97, 1218-1224 (2012).
-
(2012)
Haematologica
, vol.97
, pp. 1218-1224
-
-
Santamaria, C.1
-
52
-
-
84928588556
-
Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function
-
Pobezinsky, L. A. et al. Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function. Nat. Immunol. 16, 517-524 (2015).
-
(2015)
Nat. Immunol.
, vol.16
, pp. 517-524
-
-
Pobezinsky, L.A.1
-
53
-
-
84928239791
-
Lin28b promotes fetal B lymphopoiesis through the transcription factor Arid3a
-
Zhou, Y. et al. Lin28b promotes fetal B lymphopoiesis through the transcription factor Arid3a. J. Exp. Med. 212, 569-580 (2015).
-
(2015)
J. Exp. Med.
, vol.212
, pp. 569-580
-
-
Zhou, Y.1
-
54
-
-
84881460310
-
The Lin28b-let-7-Hmga2 axis determines the higher selfrenewal potential of fetal haematopoietic stem cells
-
Copley, M. R. et al. The Lin28b-let-7-Hmga2 axis determines the higher selfrenewal potential of fetal haematopoietic stem cells. Nat. Cell Biol. 15, 916-925 (2013).
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 916-925
-
-
Copley, M.R.1
-
55
-
-
34250883337
-
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis
-
North, T. E. et al. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature 447, 1007-1011 (2007).
-
(2007)
Nature
, vol.447
, pp. 1007-1011
-
-
North, T.E.1
-
56
-
-
84937820643
-
Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment
-
Li, P. et al. Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature 523, 468-471 (2015).
-
(2015)
Nature
, vol.523
, pp. 468-471
-
-
Li, P.1
-
57
-
-
0026606650
-
Leukotriene B4 stimulates c-fos and c-jun gene transcription and AP-1 binding activity in human monocytes
-
Stankova, J. & Rola-Pleszczynski, M. Leukotriene B4 stimulates c-fos and c-jun gene transcription and AP-1 binding activity in human monocytes. Biochem. J. 282(Pt 3), 625-629 (1992).
-
(1992)
Biochem. J.
, vol.282
, pp. 625-629
-
-
Stankova, J.1
Rola-Pleszczynski, M.2
-
58
-
-
33751113286
-
Leukotriene receptors in atherosclerosis
-
Back, M. & Hansson, G. K. Leukotriene receptors in atherosclerosis. Ann. Med. 38, 493-502 (2006).
-
(2006)
Ann. Med.
, vol.38
, pp. 493-502
-
-
Back, M.1
Hansson, G.K.2
-
59
-
-
33745190052
-
The 5 lipoxygenase system in the vasculature: Emerging role in health and disease
-
Osher, E., Weisinger, G., Limor, R., Tordjman, K. & Stern, N. The 5 lipoxygenase system in the vasculature: emerging role in health and disease. Mol. Cell. Endocrinol. 252, 201-206 (2006).
-
(2006)
Mol. Cell. Endocrinol.
, vol.252
, pp. 201-206
-
-
Osher, E.1
Weisinger, G.2
Limor, R.3
Tordjman, K.4
Stern, N.5
-
60
-
-
84879420249
-
Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo
-
Lammermann, T. et al. Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo. Nature 498, 371-375 (2013).
-
(2013)
Nature
, vol.498
, pp. 371-375
-
-
Lammermann, T.1
-
61
-
-
84937634493
-
Leukotriene B4-neutrophil elastase axis drives neutrophil reverse transendothelial cell migration in vivo
-
Colom, B. et al. Leukotriene B4-neutrophil elastase axis drives neutrophil reverse transendothelial cell migration in vivo. Immunity 42, 1075-1086 (2015).
-
(2015)
Immunity
, vol.42
, pp. 1075-1086
-
-
Colom, B.1
-
62
-
-
33745924140
-
Novel treatment options for inflammatory bowel disease: Targeting alpha 4 integrin
-
Lanzarotto, F., Carpani, M., Chaudhary, R. & Ghosh, S. Novel treatment options for inflammatory bowel disease: targeting alpha 4 integrin. Drugs 66, 1179-1189 (2006).
-
(2006)
Drugs
, vol.66
, pp. 1179-1189
-
-
Lanzarotto, F.1
Carpani, M.2
Chaudhary, R.3
Ghosh, S.4
-
63
-
-
17644398787
-
Anti-alpha4 integrin therapy for multiple sclerosis: Mechanisms and rationale
-
Rice, G. P., Hartung, H. P. & Calabresi, P. A. Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale. Neurology 64, 1336-1342 (2005).
-
(2005)
Neurology
, vol.64
, pp. 1336-1342
-
-
Rice, G.P.1
Hartung, H.P.2
Calabresi, P.A.3
-
64
-
-
0033672656
-
Fetal and adult hematopoietic stem cells require beta1 integrin function for colonizing fetal liver, spleen, and bone marrow
-
Potocnik, A. J., Brakebusch, C. & Fassler, R. Fetal and adult hematopoietic stem cells require beta1 integrin function for colonizing fetal liver, spleen, and bone marrow. Immunity 12, 653-663 (2000).
-
(2000)
Immunity
, vol.12
, pp. 653-663
-
-
Potocnik, A.J.1
Brakebusch, C.2
Fassler, R.3
-
65
-
-
84896973126
-
TGF-beta activation and function in immunity
-
Travis, M. A. & Sheppard, D. TGF-beta activation and function in immunity. Annu. Rev. Immunol. 32, 51-82 (2014).
-
(2014)
Annu. Rev. Immunol.
, vol.32
, pp. 51-82
-
-
Travis, M.A.1
Sheppard, D.2
-
66
-
-
2142654329
-
MicroRNA-directed cleavage of HOXB8 mRNA
-
Yekta, S., Shih, I. H. & Bartel, D. P. MicroRNA-directed cleavage of HOXB8 mRNA. Science 304, 594-596 (2004).
-
(2004)
Science
, vol.304
, pp. 594-596
-
-
Yekta, S.1
Shih, I.H.2
Bartel, D.P.3
-
67
-
-
84890571063
-
Acetylation of p53 stimulates MIRNA processing and determines cell survival following genotoxic stress
-
Chang, J. et al. Acetylation of p53 stimulates MIRNA processing and determines cell survival following genotoxic stress. EMBO J. 32, 3192-3205 (2013).
-
(2013)
EMBO J.
, vol.32
, pp. 3192-3205
-
-
Chang, J.1
-
68
-
-
84938592019
-
Single-cell resolution of morphological changes in hemogenic endothelium
-
Bos, F. L., Hawkins, J. S. & Zovein, A. C. Single-cell resolution of morphological changes in hemogenic endothelium. Development 142, 2719-2724 (2015).
-
(2015)
Development
, vol.142
, pp. 2719-2724
-
-
Bos, F.L.1
Hawkins, J.S.2
Zovein, A.C.3
-
69
-
-
0036916440
-
Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
-
Schmitt, T. M. & Zuniga-Pflucker, J. C. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity 17, 749-756 (2002).
-
(2002)
Immunity
, vol.17
, pp. 749-756
-
-
Schmitt, T.M.1
Zuniga-Pflucker, J.C.2
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