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Volumn 123, Issue 14, 2014, Pages 2161-2171

Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; MITOGEN ACTIVATED PROTEIN KINASE; SMAD4 PROTEIN;

EID: 84899128804     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-09-526053     Document Type: Article
Times cited : (20)

References (46)
  • 1
    • 84886299230 scopus 로고    scopus 로고
    • Erythro-myeloid progenitors: "definitive" hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells
    • Frame JM, McGrath KE, Palis J. Erythro-myeloid progenitors: "definitive" hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells. Blood Cells Mol Dis. 2013;51(4):220-225.
    • (2013) Blood Cells Mol Dis , vol.51 , Issue.4 , pp. 220-225
    • Frame, J.M.1    McGrath, K.E.2    Palis, J.3
  • 3
    • 84872485255 scopus 로고    scopus 로고
    • The biochemistry of hematopoietic stem cell development
    • Kaimakis P, Crisan M, Dzierzak E. The biochemistry of hematopoietic stem cell development. Biochim Biophys Acta. 2013; 1830(2):2395-2403.
    • (2013) Biochim Biophys Acta , vol.1830 , Issue.2 , pp. 2395-2403
    • Kaimakis, P.1    Crisan, M.2    Dzierzak, E.3
  • 4
  • 5
    • 17744416048 scopus 로고    scopus 로고
    • In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos
    • DOI 10.1016/S1074-7613(00)80581-6
    • Nishikawa SI, Nishikawa S, Kawamoto H, et al. In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos. Immunity. 1998;8(6):761-769. (Pubitemid 28294523)
    • (1998) Immunity , vol.8 , Issue.6 , pp. 761-769
    • Nishikawa, S.-I.1    Nishikawa, S.2    Kawamoto, H.3    Yoshida, H.4    Kizumoto, M.5    Kataoka, H.6    Katsura, Y.7
  • 6
    • 56549101520 scopus 로고    scopus 로고
    • Fate tracing reveals the endothelial origin of hematopoietic stem cells
    • Zovein AC, Hofmann JJ, Lynch M, et al. Fate tracing reveals the endothelial origin of hematopoietic stem cells. Cell Stem Cell. 2008; 3(6):625-636.
    • (2008) Cell Stem Cell , vol.3 , Issue.6 , pp. 625-636
    • Zovein, A.C.1    Hofmann, J.J.2    Lynch, M.3
  • 7
    • 60149100010 scopus 로고    scopus 로고
    • Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter
    • Chen MJ, Yokomizo T, Zeigler BM, Dzierzak E, Speck NA. Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter. Nature. 2009;457(7231):887-891.
    • (2009) Nature , vol.457 , Issue.7231 , pp. 887-891
    • Chen, M.J.1    Yokomizo, T.2    Zeigler, B.M.3    Dzierzak, E.4    Speck, N.A.5
  • 8
    • 60149110371 scopus 로고    scopus 로고
    • The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage
    • Lancrin C, Sroczynska P, Stephenson C, Allen T, Kouskoff V, Lacaud G. The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage. Nature. 2009; 457(7231):892-895.
    • (2009) Nature , vol.457 , Issue.7231 , pp. 892-895
    • Lancrin, C.1    Sroczynska, P.2    Stephenson, C.3    Allen, T.4    Kouskoff, V.5    Lacaud, G.6
  • 9
    • 78049326155 scopus 로고    scopus 로고
    • Three-dimensionalcartography of hematopoietic clusters in the vasculature of whole mouse embryos
    • Yokomizo T, Dzierzak E. Three-dimensionalcartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development. 2010;137(21): 3651-3661.
    • (2010) Development , vol.137 , Issue.21 , pp. 3651-3661
    • Yokomizo, T.1    Dzierzak, E.2
  • 10
    • 82755185961 scopus 로고    scopus 로고
    • Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells
    • Chen MJ, Li Y, De Obaldia ME, et al. Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells. Cell Stem Cell. 2011;9(6): 541-552.
    • (2011) Cell Stem Cell , vol.9 , Issue.6 , pp. 541-552
    • Chen, M.J.1    Li, Y.2    De Obaldia, M.E.3
  • 11
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • DOI 10.1038/nature02006
    • Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature. 2003;425(6958):577-584. (Pubitemid 37280136)
    • (2003) Nature , vol.425 , Issue.6958 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 12
    • 37549008253 scopus 로고    scopus 로고
    • BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway
    • Lengerke C, Schmitt S, Bowman TV, et al. BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. Cell Stem Cell. 2008; 2(1):72-82.
    • (2008) Cell Stem Cell , vol.2 , Issue.1 , pp. 72-82
    • Lengerke, C.1    Schmitt, S.2    Bowman, T.V.3
  • 13
    • 70349833632 scopus 로고    scopus 로고
    • Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling
    • Söderberg SS, Karlsson G, Karlsson S. Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling. Ann N Y Acad Sci. 2009;1176:55-69.
    • (2009) Ann N Y Acad Sci , vol.1176 , pp. 55-69
    • Söderberg, S.S.1    Karlsson, G.2    Karlsson, S.3
  • 14
    • 38049138738 scopus 로고    scopus 로고
    • Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells
    • Durand C, Robin C, Bollerot K, Baron MH, Ottersbach K, Dzierzak E. Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells. Proc Natl Acad Sci U S A. 2007;104(52):20838-20843.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.52 , pp. 20838-20843
    • Durand, C.1    Robin, C.2    Bollerot, K.3    Baron, M.H.4    Ottersbach, K.5    Dzierzak, E.6
  • 15
    • 33749379585 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor 1A signalling is despensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation
    • DOI 10.1242/dev.02499
    • Park C, Lavine K, Mishina Y, Deng CX, Ornitz DM, Choi K. Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation. Development. 2006;133(17):3473-3484. (Pubitemid 44501849)
    • (2006) Development , vol.133 , Issue.17 , pp. 3473-3484
    • Park, C.1    Lavine, K.2    Mishina, Y.3    Deng, C.-X.4    Ornitz, D.M.5    Choi, K.6
  • 16
    • 84866443757 scopus 로고    scopus 로고
    • Hematopoietic stem cell development requires transient Wnt/b-catenin activity
    • Ruiz-Herguido C, Guiu J, D'Altri T, et al. Hematopoietic stem cell development requires transient Wnt/b-catenin activity. J Exp Med. 2012; 209(8):1457-1468.
    • (2012) J Exp Med , vol.209 , Issue.8 , pp. 1457-1468
    • Ruiz-Herguido, C.1    Guiu, J.2    D'Altri, T.3
  • 17
    • 84890847135 scopus 로고    scopus 로고
    • Gata2 is required for HSC generation and survival
    • de Pater E, Kaimakis P, Vink CS, et al. Gata2 is required for HSC generation and survival. J Exp Med. 2013;210(13):2843-2850.
    • (2013) J Exp Med , vol.210 , Issue.13 , pp. 2843-2850
    • De Pater, E.1    Kaimakis, P.2    Vink, C.S.3
  • 18
    • 0036193069 scopus 로고    scopus 로고
    • Generation of Smad4/Dpc4 conditional knockout mice
    • DOI 10.1002/gene.10029
    • Yang X, Li C, Herrera PL, Deng CX. Generation of Smad4/Dpc4 conditional knockout mice. Genesis. 2002;32(2):80-81. (Pubitemid 34211702)
    • (2002) Genesis , vol.32 , Issue.2 , pp. 80-81
    • Yang, X.1    Li, C.2    Herrera, P.-L.3    Deng, C.-X.4
  • 20
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain [1]
    • DOI 10.1038/5007
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet. 1999; 21(1):70-71. (Pubitemid 29036285)
    • (1999) Nature Genetics , vol.21 , Issue.1 , pp. 70-71
    • Soriano, P.1
  • 22
    • 3042856262 scopus 로고    scopus 로고
    • Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
    • Srinivas S, Watanabe T, Lin CS, et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol. 2001;1:4.
    • (2001) BMC Dev Biol , vol.1 , pp. 4
    • Srinivas, S.1    Watanabe, T.2    Lin, C.S.3
  • 24
    • 84868364943 scopus 로고    scopus 로고
    • Mouse embryonic head as a site for hematopoietic stem cell development
    • Li Z, Lan Y, He W, et al. Mouse embryonic head as a site for hematopoietic stem cell development. Cell Stem Cell. 2012;11(5):663-675.
    • (2012) Cell Stem Cell , vol.11 , Issue.5 , pp. 663-675
    • Li, Z.1    Lan, Y.2    He, W.3
  • 25
    • 0030595341 scopus 로고    scopus 로고
    • Definitive hematopoiesis is autonomously initiated by the AGM region
    • DOI 10.1016/S0092-8674(00)80165-8
    • Medvinsky A, Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell. 1996;86(6):897-906. (Pubitemid 26336794)
    • (1996) Cell , vol.86 , Issue.6 , pp. 897-906
    • Medvinsky, A.1    Dzierzak, E.2
  • 26
    • 30144434921 scopus 로고    scopus 로고
    • Runx1 function in hematopoiesis is required in cells that express Tek
    • DOI 10.1182/blood-2005-05-1955
    • Li Z, Chen MJ, Stacy T, Speck NA. Runx1 function in hematopoiesis is required in cells that express Tek. Blood. 2006;107(1):106-110. (Pubitemid 43053530)
    • (2006) Blood , vol.107 , Issue.1 , pp. 106-110
    • Li, Z.1    Chen, M.J.2    Stacy, T.3    Speck, N.A.4
  • 27
    • 73949149029 scopus 로고    scopus 로고
    • The differential activities of Runx1 promoters define milestones during embryonic hematopoiesis
    • Sroczynska P, Lancrin C, Kouskoff V, Lacaud G. The differential activities of Runx1 promoters define milestones during embryonic hematopoiesis. Blood. 2009;114(26):5279-5289.
    • (2009) Blood , vol.114 , Issue.26 , pp. 5279-5289
    • Sroczynska, P.1    Lancrin, C.2    Kouskoff, V.3    Lacaud, G.4
  • 28
    • 77951078473 scopus 로고    scopus 로고
    • Nonredundant roles for Runx1 alternative promoters reflect their activity at discrete stages of developmental hematopoiesis
    • Bee T, Swiers G, Muroi S, et al. Nonredundant roles for Runx1 alternative promoters reflect their activity at discrete stages of developmental hematopoiesis. Blood. 2010;115(15):3042-3050.
    • (2010) Blood , vol.115 , Issue.15 , pp. 3042-3050
    • Bee, T.1    Swiers, G.2    Muroi, S.3
  • 30
    • 35548985414 scopus 로고    scopus 로고
    • Normal erythropoiesis but severe polyposis and bleeding anemia in Smad4-deficient mice
    • Pan D, Schomber T, Kalberer CP, et al. Normal erythropoiesis but severe polyposis and bleeding anemia in Smad4-deficient mice. Blood. 2007; 110(8):3049-3055.
    • (2007) Blood , vol.110 , Issue.8 , pp. 3049-3055
    • Pan, D.1    Schomber, T.2    Kalberer, C.P.3
  • 31
    • 79952525332 scopus 로고    scopus 로고
    • Endothelial Smad4 maintains cerebrovascular integrity by activating N-cadherin through cooperation with Notch
    • Li F, Lan Y, Wang Y, et al. Endothelial Smad4 maintains cerebrovascular integrity by activating N-cadherin through cooperation with Notch. Dev Cell. 2011;20(3):291-302.
    • (2011) Dev Cell , vol.20 , Issue.3 , pp. 291-302
    • Li, F.1    Lan, Y.2    Wang, Y.3
  • 32
    • 84867353401 scopus 로고    scopus 로고
    • Signaling from the sympathetic nervous system regulates hematopoietic stem cell emergence during embryogenesis
    • Fitch SR, Kimber GM, Wilson NK, et al. Signaling from the sympathetic nervous system regulates hematopoietic stem cell emergence during embryogenesis. Cell Stem Cell. 2012;11(4): 554-566.
    • (2012) Cell Stem Cell , vol.11 , Issue.4 , pp. 554-566
    • Fitch, S.R.1    Kimber, G.M.2    Wilson, N.K.3
  • 33
    • 84875605477 scopus 로고    scopus 로고
    • Endotheliomesenchymal interaction controls runx1 expression and modulates the notch pathway to initiate aortic hematopoiesis
    • Richard C, Drevon C, Canto PY, et al. Endotheliomesenchymal interaction controls runx1 expression and modulates the notch pathway to initiate aortic hematopoiesis. Dev Cell. 2013; 24(6):600-611.
    • (2013) Dev Cell , vol.24 , Issue.6 , pp. 600-611
    • Richard, C.1    Drevon, C.2    Canto, P.Y.3
  • 34
    • 69049109901 scopus 로고    scopus 로고
    • Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development
    • Peeters M, Ottersbach K, Bollerot K, et al. Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development. Development. 2009;136(15):2613-2621.
    • (2009) Development , vol.136 , Issue.15 , pp. 2613-2621
    • Peeters, M.1    Ottersbach, K.2    Bollerot, K.3
  • 35
    • 70449464598 scopus 로고    scopus 로고
    • Control of KIT signalling in male germ cells: What can we learn from other systems?
    • Mithraprabhu S, Loveland KL. Control of KIT signalling in male germ cells: what can we learn from other systems? Reproduction. 2009;138(5): 743-757.
    • (2009) Reproduction , vol.138 , Issue.5 , pp. 743-757
    • Mithraprabhu, S.1    Loveland, K.L.2
  • 36
    • 2442631556 scopus 로고    scopus 로고
    • Stem Cell Factor/c-kit Signaling Promotes the Survival, Migration, and Capillary Tube Formation of Human Umbilical Vein Endothelial Cells
    • DOI 10.1074/jbc.M311643200
    • Matsui J, Wakabayashi T, Asada M, Yoshimatsu K, Okada M. Stem cell factor/c-kit signaling promotes the survival, migration, and capillary tube formation of human umbilical vein endothelial cells. J Biol Chem. 2004;279(18): 18600-18607. (Pubitemid 38623281)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.18 , pp. 18600-18607
    • Matsui, J.1    Wakabayashi, T.2    Asada, M.3    Yoshimatsu, K.4    Okada, M.5
  • 37
    • 84892180066 scopus 로고    scopus 로고
    • Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control
    • Marcelo KL, Sills TM, Coskun S, et al. Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control. Dev Cell. 2013;27(5):504-515.
    • (2013) Dev Cell , vol.27 , Issue.5 , pp. 504-515
    • Marcelo, K.L.1    Sills, T.M.2    Coskun, S.3
  • 38
    • 3042733135 scopus 로고    scopus 로고
    • A hierarchical order of factors in the generation of FLK1- and SCL- expressing hematopoietic and endothelial progenitors from embryonic stem cells
    • DOI 10.1242/dev.01130
    • Park C, Afrikanova I, Chung YS, et al. A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells. Development. 2004;131(11):2749-2762. (Pubitemid 38877906)
    • (2004) Development , vol.131 , Issue.11 , pp. 2749-2762
    • Park, C.1    Afrikanova, I.2    Chung, Y.S.3    Zhang, W.J.4    Arentson, E.5    Fong, G.H.6    Rosendahl, A.7    Choi, K.8
  • 40
    • 84863012550 scopus 로고    scopus 로고
    • BMP4 Signaling Acts via dual-specificity phosphatase 9 to control ERK activity in mouse embryonic stem cells
    • Li Z, Fei T, Zhang J, et al. BMP4 Signaling Acts via dual-specificity phosphatase 9 to control ERK activity in mouse embryonic stem cells. Cell Stem Cell. 2012;10(2):171-182.
    • (2012) Cell Stem Cell , vol.10 , Issue.2 , pp. 171-182
    • Li, Z.1    Fei, T.2    Zhang, J.3
  • 42
    • 84886238362 scopus 로고    scopus 로고
    • Dorso-ventral contributions in the formation of the embryonic aorta and the control of aortic hematopoiesis
    • Jaffredo T, Lempereur A, Richard C, et al. Dorso-ventral contributions in the formation of the embryonic aorta and the control of aortic hematopoiesis. Blood Cells Mol Dis. 2013;51(4): 232-238.
    • (2013) Blood Cells Mol Dis , vol.51 , Issue.4 , pp. 232-238
    • Jaffredo, T.1    Lempereur, A.2    Richard, C.3
  • 43
    • 84875325826 scopus 로고    scopus 로고
    • Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells
    • Mirshekar-Syahkal B, Haak E, Kimber GM, et al. Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells. Haematologica. 2013;98(2):163-171.
    • (2013) Haematologica , vol.98 , Issue.2 , pp. 163-171
    • Mirshekar-Syahkal, B.1    Haak, E.2    Kimber, G.M.3
  • 44
    • 0032482202 scopus 로고    scopus 로고
    • PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate
    • DOI 10.1083/jcb.141.3.805
    • Hirschi KK, Rohovsky SA, D'Amore PA. PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate. J Cell Biol. 1998;141(3): 805-814. (Pubitemid 28217923)
    • (1998) Journal of Cell Biology , vol.141 , Issue.3 , pp. 805-814
    • Hirschi, K.K.1    Rohovsky, S.A.2    D'Amore, P.A.3
  • 45
    • 0032973230 scopus 로고    scopus 로고
    • Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact
    • Hirschi KK, Rohovsky SA, Beck LH, Smith SR, D'Amore PA. Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact. Circ Res. 1999;84(3): 298-305. (Pubitemid 29095570)
    • (1999) Circulation Research , vol.84 , Issue.3 , pp. 298-305
    • Hirschi, K.K.1    Rohovsky, S.A.2    Beck, L.H.3    Smith, S.R.4    D'Amore, P.A.5
  • 46
    • 0032768156 scopus 로고    scopus 로고
    • Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
    • Hellström M, Kalén M, Lindahl P, Abramsson A, Betsholtz C. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development. 1999; 126(14):3047-3055. (Pubitemid 29378170)
    • (1999) Development , vol.126 , Issue.14 , pp. 3047-3055
    • Hellstrom, M.1    Kalen, M.2    Lindahl, P.3    Abramsson, A.4    Betsholtz, C.5


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