Impact of zinc oxide nanoparticles on an in vitro model of the human air-blood barrier

Toxicology Letters

Volumn 279, Issue , 2017, Pages 22-32

  Bengalli, Rossella ^a   Gualtieri, Maurizio ^b   Capasso, Laura ^a   Urani, Chiara ^a   Camatini, Marina ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b ENEA   (Italy)

Author keywords

Air blood barrier; Endothelial response; Inflammation; Lung toxicity; ZnO nanoparticles

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; INTERLEUKIN 8; METALLOTHIONEIN; SOLUBLE INTERCELLULAR ADHESION MOLECULE 1; SOLUBLE VASCULAR CELL ADHESION MOLECULE 1; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; ZINC OXIDE NANOPARTICLE; AUTACOID; ICAM1 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN; METAL NANOPARTICLE; PROTEIN ZO1; TJP1 PROTEIN, HUMAN; ZINC OXIDE;

AIR BLOOD BARRIER; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL VIABILITY; CELLS; COCULTURE; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; ELECTRIC RESISTANCE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELL LINE; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; LUNG TOXICITY; MONOCULTURE; MONOCYTE; PARTICLE SIZE; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPERNATANT; SUSPENSION; TIGHT JUNCTION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WESTERN BLOTTING; DOSE RESPONSE; DRUG EFFECTS; ELECTRIC CONDUCTIVITY; ENDOTHELIUM CELL; EPITHELIUM CELL; LUNG GAS EXCHANGE; METABOLISM; PATHOLOGY; PERMEABILITY; TUMOR CELL LINE;

BLOOD-AIR BARRIER; CELL LINE, TUMOR; COCULTURE TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; ENDOTHELIAL CELLS; EPITHELIAL CELLS; HUMANS; INFLAMMATION MEDIATORS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; INTERLEUKIN-8; METAL NANOPARTICLES; METALLOTHIONEIN; MONOCYTES; PERMEABILITY; TIGHT JUNCTIONS; VASCULAR CELL ADHESION MOLECULE-1; ZINC OXIDE; ZONULA OCCLUDENS-1 PROTEIN;

EID: 85025684822     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2017.07.877     Document Type: Article

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