Gambogic acid improves non-small cell lung cancer progression by inhibition of mTOR signaling pathway

Kaohsiung Journal of Medical Sciences

Volumn 33, Issue 11, 2017, Pages 543-549

  Zhao, Teng ^a   Wang, Hong Jian ^b   Zhao, Wen Wen ^c   Sun, Yi Ling ^b   Hu, Li Kuan ^a  

^a SHANDONG UNIVERSITY   (China)

^b TENGZHOU CENTRAL PEOPLE S HOSPITAL   (China)

^c Shandong Maternal and Child Health Care Hospital   (China)

Author keywords

Autophagy; Cell death; Gambogic acid; Multidrug resistance

Indexed keywords

3 METHYLADENINE; BECLIN 1; CELL PROTEIN; CHLOROQUINE; CISPLATIN; GAMBOGIC ACID; LC3I PROTEIN; LC3II PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MULTIDRUG RESISTANCE PROTEIN; PROTEIN BCL 2; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE; UNCLASSIFIED DRUG; 3-METHYLADENINE; ADENINE; ANTINEOPLASTIC AGENT; LIGHT CHAIN 3, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; MTOR PROTEIN, HUMAN; PLANT EXTRACT; PROTEIN S6; TARGET OF RAPAMYCIN KINASE; XANTHONE DERIVATIVE;

A-549 CELL LINE; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER GROWTH; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; MTOR SIGNALING; MTT ASSAY; NCI-H460 CELL LINE; NON SMALL CELL LUNG CANCER; PROTEIN EXPRESSION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CHEMISTRY; DRUG COMBINATION; DRUG EFFECT; DRUG POTENTIATION; GARCINIA; GENE EXPRESSION REGULATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

A549 CELLS; ADENINE; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; CHLOROQUINE; CISPLATIN; DRUG COMBINATIONS; DRUG SYNERGISM; GARCINIA; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES; XANTHONES;

EID: 85025631598     PISSN: 1607551X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.kjms.2017.06.013     Document Type: Article

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