Increased expression of transcription factor EB (TFEB) is associated with autophagy, migratory phenotype and poor prognosis in non-small cell lung cancer

Lung Cancer

Volumn 90, Issue 1, 2015, Pages 98-105

  Giatromanolaki, Alexandra ^a   Kalamida, Dimitra ^a   Sivridis, Efthimios ^a   Karagounis, Ilias V ^a   Gatter, Kevin C ^b   Harris, Adrian L ^c   Koukourakis, Michael I ^a  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Autophagy; Cathepsin D; LAMP2a; Lung cancer; Lysosomes; TFEB

Indexed keywords

BAFILOMYCIN; CATHEPSIN D; HYDROLASE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MITOMYCIN; PROTEIN BNIP3; PROTEIN P62; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EB; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; CTSD PROTEIN, HUMAN; LAMP2 PROTEIN, HUMAN; TFEB PROTEIN, HUMAN;

A549 CELL LINE; ADULT; AGED; ARTICLE; AUTOPHAGY; BIOGENESIS; BRONCHUS MUCOSA; CANCER PROGNOSIS; CELL MIGRATION; CELL PROLIFERATION; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL; LYSOSOME; MAJOR CLINICAL STUDY; MALE; NON SMALL CELL LUNG CANCER; OUTCOME ASSESSMENT; PHENOTYPE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL; TISSUE SECTION; VERY ELDERLY; WESTERN BLOTTING; BIOSYNTHESIS; CANCER STAGING; CARCINOMA, NON-SMALL-CELL LUNG; CELL MOTION; ENZYMOLOGY; GENETICS; LUNG NEOPLASMS; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; PROGNOSIS; TREATMENT OUTCOME; TUMOR CELL LINE;

ADULT; AGED; AGED, 80 AND OVER; AUTOPHAGY; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CARCINOMA, NON-SMALL-CELL LUNG; CATHEPSIN D; CELL LINE, TUMOR; CELL MOVEMENT; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 2; LYSOSOMES; MALE; MIDDLE AGED; NEOPLASM STAGING; PHENOTYPE; PROGNOSIS; TREATMENT OUTCOME;

EID: 84940958227     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2015.07.008     Document Type: Article

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