Dual inhibition of PI3K/Akt/mTOR pathway and role of autophagy in non-small cell lung cancer cells

Tuberculosis and Respiratory Diseases

Volumn 72, Issue 4, 2012, Pages 343-351

  Jeong, Eun Hui ^a   Choi, Hyeong Sim ^a   Lee, Tae Gul ^a   Kim, Hye Ryoun ^a   Kim, Cheol Hyeon ^a  

^a Korea Cancer Center Hospital   (South Korea)

Author keywords

Carcinoma, non small cell lung; Phosphatidylinositol 3 kinases; TOR serine threonine kinases

Indexed keywords

4 [2 (4 AMINO 1,2,5 OXADIAZOL 3 YL) 1 ETHYL 7 (3 PIPERIDINYLMETHOXY) 1H IMIDAZO[4,5 C]PYRIDIN 4 YL] 2 METHYL 3 BUTYN 2 OL; ACRIDINE ORANGE; CASPASE 3; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN KINASE B; TEMSIROLIMUS;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME INHIBITION; FLOW CYTOMETRY; LUNG NON SMALL CELL CANCER; NICK END LABELING;

EID: 84867459604     PISSN: 17383536     EISSN: None     Source Type: Journal    
DOI: 10.4046/trd.2012.72.4.343     Document Type: Article

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