Extreme trait whole-genome sequencing identifies PTPRO as a novel candidate gene in emphysema with severe airflow obstruction

American Journal of Respiratory and Critical Care Medicine

Volumn 196, Issue 2, 2017, Pages 159-171

  Radder, Josiah E ^a   Zhang, Yingze ^a   Gregory, Alyssa D ^a   Yu, Shibing ^a   Kelly, Neil J ^a   Leader, Joseph K ^a   Kaminski, Naftali ^b   Sciurba, Frank C ^a   Shapiro, Steven D ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chronic obstructive pulmonary disease; Emphysema; Genetic association studies; Whole genome sequencing

Indexed keywords

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; EMPHYSEMA; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIATION; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PTPRO GENE; SINGLE NUCLEOTIDE POLYMORPHISM; WHOLE GENOME SEQUENCING; ZNF816 GENE; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; LUNG EMPHYSEMA; MIDDLE AGED; PROCEDURES; SEVERITY OF ILLNESS INDEX;

PTPRO PROTEIN, HUMAN; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE;

AGED; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 3; SEVERITY OF ILLNESS INDEX;

EID: 85025176301     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201606-1147OC     Document Type: Article

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