A benzylideneacetophenone derivative induces apoptosis of radiation-resistant human breast cancer cells via oxidative stress

Biomolecules and Therapeutics

Volumn 25, Issue 4, 2017, Pages 404-410

  Park, Jeong Eon ^a   Piao, Mei Jing ^a   Kang, Kyoung Ah ^a   Shilnikova, Kristina ^a   Hyun, Yu Jae ^a   Oh, Sei Kwan ^b   Jeong, Yong Joo ^c   Chae, Sungwook ^d   Hyun, Jin Won ^a  

^a Jeju National University   (South Korea)

^b Ewha Womans University School of Medicine   (South Korea)

^c Kookmin University   (South Korea)

^d Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

Apoptosis; Benzylideneacetophenone derivative; Radiation resistance; Reactive oxygen species

Indexed keywords

1 (4 HYDROXY 3 METHOXYPHENYL) HEPT 1 EN 3 ONE; CASPASE 3; CASPASE 9; CHALCONE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL VIABILITY ASSAY; COMET ASSAY; DNA FRAGMENTATION; DNA STRAND BREAKAGE; DRUG CYTOTOXICITY; IC50; LIPID PEROXIDATION; MDA-MB-231 CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PROTEIN CARBONYLATION; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RADIOSENSITIVITY; WESTERN BLOTTING;

EID: 85023600396     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2017.010     Document Type: Article

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