SCOPUS 정보 검색 플랫폼

Volumn 53, Issue 43, 2017, Pages 5806-5809

Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition

(12) Li, Guo Bo a,b Brem, Jürgen a Lesniak, Robert a Abboud, Martine I a Lohans, Christopher T a Clifton, Ian J a Yang, Sheng Yong b Jiménez Castellanos, Juan Carlos c Avison, Matthew B c Spencer, James c McDonough, Michael A a Schofield, Christopher J a

a UNIVERSITY OF OXFORD (United Kingdom)

b SICHUAN UNIVERSITY (China)

c UNIVERSITY OF BRISTOL (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE INHIBITOR; CAPTOPRIL; ISOQUINOLINE DERIVATIVE; MEROPENEM; METALLO BETA LACTAMASE; METALLO BETA LACTAMASE BCII; METALLO BETA LACTAMASE CPHA; METALLO BETA LACTAMASE IMP 1; METALLO BETA LACTAMASE SPM 1; METALLO BETA LACTAMASE VIM 1; METALLO BETA LACTAMASE VIM 2; METALLO BETA LACTAMASE VIM 5; THIOL; UNCLASSIFIED DRUG; ZINC ION; BETA LACTAMASE;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; BINDING AFFINITY; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; DRUG SYNTHESIS; ENTEROBACTER AEROGENES; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; METAL BINDING; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STATIC ELECTRICITY; STRUCTURE ACTIVITY RELATION; CONFORMATION; DOSE RESPONSE; ENZYMOLOGY; METABOLISM; MOLECULAR MODEL; X RAY CRYSTALLOGRAPHY;

BETA-LACTAMASE INHIBITORS; BETA-LACTAMASES; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROBACTER AEROGENES; ESCHERICHIA COLI; ISOQUINOLINES; KLEBSIELLA PNEUMONIAE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85021770905 PISSN: 13597345 EISSN: 1364548X Source Type: Journal
DOI: 10.1039/c7cc02394d Document Type: Article

Times cited : (32)

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