메뉴 건너뛰기




Volumn 127, Issue 7, 2017, Pages 2789-2804

Tregs restrain dendritic cell autophagy to ameliorate autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; HYBRID PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FOXP3; CTLA4 PROTEIN, HUMAN; CTLA4 PROTEIN, MOUSE; MAP1LC3 PROTEIN, MOUSE; MAP1LC3B PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN;

EID: 85021731404     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI92079     Document Type: Article
Times cited : (95)

References (63)
  • 1
    • 77950349016 scopus 로고    scopus 로고
    • Th17 and regulatory T cells in mediating and restraining inflammation
    • Littman DR, Rudensky AY. Th17 and regulatory T cells in mediating and restraining inflammation. Cell. 2010;140(6):845-858.
    • (2010) Cell , vol.140 , Issue.6 , pp. 845-858
    • Littman, D.R.1    Rudensky, A.Y.2
  • 2
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • Sakaguchi S, Yamaguchi T, Nomura T, Ono M. Regulatory T cells and immune tolerance. Cell. 2008;133(5):775-787.
    • (2008) Cell , vol.133 , Issue.5 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 3
    • 48249103057 scopus 로고    scopus 로고
    • Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
    • Onishi Y, Fehervari Z, Yamaguchi T, Sakaguchi S. Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation. Proc Natl Acad Sci U S A. 2008;105(29):10113-10118.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.29 , pp. 10113-10118
    • Onishi, Y.1    Fehervari, Z.2    Yamaguchi, T.3    Sakaguchi, S.4
  • 4
    • 29244482759 scopus 로고    scopus 로고
    • Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
    • Tang Q, et al. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol. 2006;7(1):83-92.
    • (2006) Nat Immunol , vol.7 , Issue.1 , pp. 83-92
    • Tang, Q.1
  • 5
    • 84923172437 scopus 로고    scopus 로고
    • Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming
    • Matheu MP, et al. Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming. Nat Commun. 2015;6:6219.
    • (2015) Nat Commun , vol.6 , pp. 6219
    • Matheu, M.P.1
  • 6
    • 33645067654 scopus 로고    scopus 로고
    • Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo
    • Tadokoro CE, et al. Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo. J Exp Med. 2006;203(3):505-511.
    • (2006) J Exp Med , vol.203 , Issue.3 , pp. 505-511
    • Tadokoro, C.E.1
  • 7
    • 53749094183 scopus 로고    scopus 로고
    • CTLA-4 control over Foxp3+ regulatory T cell function
    • Wing K, et al. CTLA-4 control over Foxp3+ regulatory T cell function. Science. 2008;322(5899):271-275.
    • (2008) Science , vol.322 , Issue.5899 , pp. 271-275
    • Wing, K.1
  • 8
    • 84862888230 scopus 로고    scopus 로고
    • Autophagy: An emerging immunological paradigm
    • Deretic V. Autophagy: an emerging immunological paradigm. J Immunol. 2012;189(1):15-20.
    • (2012) J Immunol , vol.189 , Issue.1 , pp. 15-20
    • Deretic, V.1
  • 9
    • 79955529454 scopus 로고    scopus 로고
    • Trans-endocytosis of CD80 and CD86: A molecular basis for the cell-extrinsic function of CTLA-4
    • Qureshi OS, et al. Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. Science. 2011;332(6029):600-603.
    • (2011) Science , vol.332 , Issue.6029 , pp. 600-603
    • Qureshi, O.S.1
  • 10
    • 1642396607 scopus 로고    scopus 로고
    • Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells
    • Munn DH, Sharma MD, Mellor AL. Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells. J Immunol. 2004;172(7):4100-4110.
    • (2004) J Immunol , vol.172 , Issue.7 , pp. 4100-4110
    • Munn, D.H.1    Sharma, M.D.2    Mellor, A.L.3
  • 11
    • 0036852170 scopus 로고    scopus 로고
    • CTLA-4-Ig regulates tryptophan catabolism in vivo
    • Grohmann U, et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol. 2002;3(11):1097-1101.
    • (2002) Nat Immunol , vol.3 , Issue.11 , pp. 1097-1101
    • Grohmann, U.1
  • 12
    • 34748835898 scopus 로고    scopus 로고
    • IDO and regulatory T cells: A role for reverse signalling and non-canonical NF-κB activation
    • Puccetti P, Grohmann U. IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-κB activation. Nat Rev Immunol. 2007;7(10):817-823.
    • (2007) Nat Rev Immunol , vol.7 , Issue.10 , pp. 817-823
    • Puccetti, P.1    Grohmann, U.2
  • 13
    • 34548700796 scopus 로고    scopus 로고
    • Unveiling the roles of autophagy in innate and adaptive immunity
    • Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol. 2007;7(10):767-777.
    • (2007) Nat Rev Immunol , vol.7 , Issue.10 , pp. 767-777
    • Levine, B.1    Deretic, V.2
  • 14
    • 52149099867 scopus 로고    scopus 로고
    • Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
    • Nedjic J, Aichinger M, Emmerich J, Mizushima N, Klein L. Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature. 2008;455(7211):396-400.
    • (2008) Nature , vol.455 , Issue.7211 , pp. 396-400
    • Nedjic, J.1    Aichinger, M.2    Emmerich, J.3    Mizushima, N.4    Klein, L.5
  • 15
    • 33846461678 scopus 로고    scopus 로고
    • A critical role for the autophagy gene Atg5 in T cell survival and proliferation
    • Pua HH, Dzhagalov I, Chuck M, Mizushima N, He YW. A critical role for the autophagy gene Atg5 in T cell survival and proliferation. J Exp Med. 2007;204(1):25-31.
    • (2007) J Exp Med , vol.204 , Issue.1 , pp. 25-31
    • Pua, H.H.1    Dzhagalov, I.2    Chuck, M.3    Mizushima, N.4    He, Y.W.5
  • 16
    • 33746691954 scopus 로고    scopus 로고
    • Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4
    • Espert L, et al. Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4. J Clin Invest. 2006;116(8):2161-2172.
    • (2006) J Clin Invest , vol.116 , Issue.8 , pp. 2161-2172
    • Espert, L.1
  • 17
    • 20344361954 scopus 로고    scopus 로고
    • Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
    • Dengjel J, et al. Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proc Natl Acad Sci U S A. 2005;102(22):7922-7927.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.22 , pp. 7922-7927
    • Dengjel, J.1
  • 18
    • 12844275079 scopus 로고    scopus 로고
    • Endogenous MHC class II processing of a viral nuclear antigen after autophagy
    • Paludan C, et al. Endogenous MHC class II processing of a viral nuclear antigen after autophagy. Science. 2005;307(5709):593-596.
    • (2005) Science , vol.307 , Issue.5709 , pp. 593-596
    • Paludan, C.1
  • 19
    • 33846224369 scopus 로고    scopus 로고
    • Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes
    • Schmid D, Pypaert M, Münz C. Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes. Immunity. 2007;26(1):79-92.
    • (2007) Immunity , vol.26 , Issue.1 , pp. 79-92
    • Schmid, D.1    Pypaert, M.2    Münz, C.3
  • 20
    • 76949091325 scopus 로고    scopus 로고
    • In vivo requirement for Atg5 in antigen presentation by dendritic cells
    • Lee HK, et al. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity. 2010;32(2):227-239.
    • (2010) Immunity , vol.32 , Issue.2 , pp. 227-239
    • Lee, H.K.1
  • 21
    • 84874565064 scopus 로고    scopus 로고
    • Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance
    • Aichinger M, Wu C, Nedjic J, Klein L. Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance. J Exp Med. 2013;210(2):287-300.
    • (2013) J Exp Med , vol.210 , Issue.2 , pp. 287-300
    • Aichinger, M.1    Wu, C.2    Nedjic, J.3    Klein, L.4
  • 22
    • 84931421873 scopus 로고    scopus 로고
    • De novo-induced self-antigen-specific Foxp3+ regulatory T cells impair the accumulation of inflammatory dendritic cells in draining lymph nodes
    • Alissafi T, et al. De novo-induced self-antigen-specific Foxp3+ regulatory T cells impair the accumulation of inflammatory dendritic cells in draining lymph nodes. J Immunol. 2015;194(12):5812-5824.
    • (2015) J Immunol , vol.194 , Issue.12 , pp. 5812-5824
    • Alissafi, T.1
  • 23
    • 62749144984 scopus 로고    scopus 로고
    • SiPaGene: A new repository for instant online retrieval, sharing and meta-analyses of GeneChip expression data
    • Menssen A, et al. SiPaGene: A new repository for instant online retrieval, sharing and meta-analyses of GeneChip expression data. BMC Genomics. 2009;10:98.
    • (2009) BMC Genomics , vol.10 , pp. 98
    • Menssen, A.1
  • 24
    • 43949143804 scopus 로고    scopus 로고
    • The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
    • Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell. 2008;19(5):2092-2100.
    • (2008) Mol Biol Cell , vol.19 , Issue.5 , pp. 2092-2100
    • Fujita, N.1    Itoh, T.2    Omori, H.3    Fukuda, M.4    Noda, T.5    Yoshimori, T.6
  • 25
    • 0038325675 scopus 로고    scopus 로고
    • Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate
    • Mizushima N, et al. Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J Cell Sci. 2003;116(pt 9):1679-1688.
    • (2003) J Cell Sci , vol.116 , pp. 1679-1688
    • Mizushima, N.1
  • 26
    • 85013763791 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
    • Klionsky DJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016;12(1):1-222.
    • (2016) Autophagy , vol.12 , Issue.1 , pp. 1-222
    • Klionsky, D.J.1
  • 27
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Kabeya Y, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 2000;19(21):5720-5728.
    • (2000) EMBO J , vol.19 , Issue.21 , pp. 5720-5728
    • Kabeya, Y.1
  • 28
    • 34548259958 scopus 로고    scopus 로고
    • P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    • Pankiv S, et al. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem. 2007;282(33):24131-24145.
    • (2007) J Biol Chem , vol.282 , Issue.33 , pp. 24131-24145
    • Pankiv, S.1
  • 29
    • 77949997805 scopus 로고    scopus 로고
    • Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties
    • Ponpuak M, et al. Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties. Immunity. 2010;32(3):329-341.
    • (2010) Immunity , vol.32 , Issue.3 , pp. 329-341
    • Ponpuak, M.1
  • 30
    • 84864874958 scopus 로고    scopus 로고
    • MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
    • Martina JA, Chen Y, Gucek M, Puertollano R. MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB. Autophagy. 2012;8(6):903-914.
    • (2012) Autophagy , vol.8 , Issue.6 , pp. 903-914
    • Martina, J.A.1    Chen, Y.2    Gucek, M.3    Puertollano, R.4
  • 31
    • 66449083078 scopus 로고    scopus 로고
    • ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
    • Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X. ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem. 2009;284(18):12297-12305.
    • (2009) J Biol Chem , vol.284 , Issue.18 , pp. 12297-12305
    • Ganley, I.G.1    Lam Du, H.2    Wang, J.3    Ding, X.4    Chen, S.5    Jiang, X.6
  • 33
    • 84908137655 scopus 로고    scopus 로고
    • Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells
    • Hubbard-Lucey VM, et al. Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells. Immunity. 2014;41(4):579-591.
    • (2014) Immunity , vol.41 , Issue.4 , pp. 579-591
    • Hubbard-Lucey, V.M.1
  • 34
    • 84948470045 scopus 로고    scopus 로고
    • Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy
    • Petherick KJ, et al. Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J Biol Chem. 2015;290(48):28726.
    • (2015) J Biol Chem , vol.290 , Issue.48 , pp. 28726
    • Petherick, K.J.1
  • 35
    • 65549136983 scopus 로고    scopus 로고
    • Mechanisms of Foxp3+ T regulatory cell-mediated suppression
    • Shevach EM. Mechanisms of Foxp3+ T regulatory cell-mediated suppression. Immunity. 2009;30(5):636-645.
    • (2009) Immunity , vol.30 , Issue.5 , pp. 636-645
    • Shevach, E.M.1
  • 36
    • 84964778827 scopus 로고    scopus 로고
    • Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
    • Klocke K, Sakaguchi S, Holmdahl R, Wing K. Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood. Proc Natl Acad Sci U S A. 2016;113(17):E2383-E2392.
    • (2016) Proc Natl Acad Sci U S A , vol.113 , Issue.17 , pp. E2383-E2392
    • Klocke, K.1    Sakaguchi, S.2    Holmdahl, R.3    Wing, K.4
  • 37
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell. 2010;140(3):313-326.
    • (2010) Cell , vol.140 , Issue.3 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 38
    • 4344714889 scopus 로고    scopus 로고
    • PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects
    • Patrucco E, et al. PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects. Cell. 2004;118(3):375-387.
    • (2004) Cell , vol.118 , Issue.3 , pp. 375-387
    • Patrucco, E.1
  • 39
    • 84896270874 scopus 로고    scopus 로고
    • Novel regulation of CD80/ CD86-induced phosphatidylinositol 3-kinase signaling by NOTCH1 protein in interleukin-6 and indoleamine 2,3-dioxygenase production by dendritic cells
    • Koorella C, Nair JR, Murray ME, Carlson LM, Watkins SK, Lee KP. Novel regulation of CD80/ CD86-induced phosphatidylinositol 3-kinase signaling by NOTCH1 protein in interleukin-6 and indoleamine 2,3-dioxygenase production by dendritic cells. J Biol Chem. 2014;289(11):7747-7762.
    • (2014) J Biol Chem , vol.289 , Issue.11 , pp. 7747-7762
    • Koorella, C.1    Nair, J.R.2    Murray, M.E.3    Carlson, L.M.4    Watkins, S.K.5    Lee, K.P.6
  • 40
    • 84891014899 scopus 로고    scopus 로고
    • The return of the nucleus: Transcriptional and epigenetic control of autophagy
    • Füllgrabe J, Klionsky DJ, Joseph B. The return of the nucleus: transcriptional and epigenetic control of autophagy. Nat Rev Mol Cell Biol. 2014;15(1):65-74.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , Issue.1 , pp. 65-74
    • Füllgrabe, J.1    Klionsky, D.J.2    Joseph, B.3
  • 41
    • 84874730305 scopus 로고    scopus 로고
    • Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay
    • Fiorentino L, et al. Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay. EMBO Mol Med. 2013;5(3):441-455.
    • (2013) EMBO Mol Med , vol.5 , Issue.3 , pp. 441-455
    • Fiorentino, L.1
  • 43
    • 34447629523 scopus 로고    scopus 로고
    • Innate and adaptive immunity through autophagy
    • Schmid D, Munz C. Innate and adaptive immunity through autophagy. Immunity. 2007;27(1):11-21.
    • (2007) Immunity , vol.27 , Issue.1 , pp. 11-21
    • Schmid, D.1    Munz, C.2
  • 44
    • 84907195348 scopus 로고    scopus 로고
    • Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis
    • Bhattacharya A, Parillon X, Zeng S, Han S, Eissa NT. Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis. J Biol Chem. 2014;289(38):26525-26532.
    • (2014) J Biol Chem , vol.289 , Issue.38 , pp. 26525-26532
    • Bhattacharya, A.1    Parillon, X.2    Zeng, S.3    Han, S.4    Eissa, N.T.5
  • 45
    • 84987949063 scopus 로고    scopus 로고
    • Lung inflammation stalls Th17-cell migration en route to the central nervous system during the development of experimental autoimmune encephalomyelitis
    • Kanayama M, Danzaki K, He YW, Shinohara ML. Lung inflammation stalls Th17-cell migration en route to the central nervous system during the development of experimental autoimmune encephalomyelitis. Int Immunol. 2016;28(9):463-469.
    • (2016) Int Immunol , vol.28 , Issue.9 , pp. 463-469
    • Kanayama, M.1    Danzaki, K.2    He, Y.W.3    Shinohara, M.L.4
  • 46
    • 0030060377 scopus 로고    scopus 로고
    • Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway
    • Miyazaki T, et al. Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway. Cell. 1996;84(4):531-541.
    • (1996) Cell , vol.84 , Issue.4 , pp. 531-541
    • Miyazaki, T.1
  • 47
    • 0030048126 scopus 로고    scopus 로고
    • H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection
    • Martin WD, Hicks GG, Mendiratta SK, Leva HI, Ruley HE, Van Kaer L. H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection. Cell. 1996;84(4):543-550.
    • (1996) Cell , vol.84 , Issue.4 , pp. 543-550
    • Martin, W.D.1    Hicks, G.G.2    Mendiratta, S.K.3    Leva, H.I.4    Ruley, H.E.5    Van Kaer, L.6
  • 48
    • 0034778328 scopus 로고    scopus 로고
    • Requirement for endocytic antigen processing and influence of invariant chain and H-2M deficiencies in CNS autoimmunity
    • Slavin AJ, et al. Requirement for endocytic antigen processing and influence of invariant chain and H-2M deficiencies in CNS autoimmunity. J Clin Invest. 2001;108(8):1133-1139.
    • (2001) J Clin Invest , vol.108 , Issue.8 , pp. 1133-1139
    • Slavin, A.J.1
  • 49
    • 0037090253 scopus 로고    scopus 로고
    • De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis
    • Tompkins SM, Padilla J, Dal Canto MC, Ting JP, Van Kaer L, Miller SD. De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis. J Immunol. 2002;168(8):4173-4183.
    • (2002) J Immunol , vol.168 , Issue.8 , pp. 4173-4183
    • Tompkins, S.M.1    Padilla, J.2    Dal Canto, M.C.3    Ting, J.P.4    Van Kaer, L.5    Miller, S.D.6
  • 50
    • 84925732779 scopus 로고    scopus 로고
    • The ins and outs of MHC class II-mediated antigen processing and presentation
    • Roche PA, Furuta K. The ins and outs of MHC class II-mediated antigen processing and presentation. Nat Rev Immunol. 2015;15(4):203-216.
    • (2015) Nat Rev Immunol , vol.15 , Issue.4 , pp. 203-216
    • Roche, P.A.1    Furuta, K.2
  • 51
    • 84984802042 scopus 로고    scopus 로고
    • Ubiquitin ligase March 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection
    • Liu H, et al. Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection. J Exp Med. 2016;213(9):1695-1703.
    • (2016) J Exp Med , vol.213 , Issue.9 , pp. 1695-1703
    • Liu, H.1
  • 52
    • 84963812824 scopus 로고    scopus 로고
    • Abatacept inhibits T cell priming by inducing of a unique transcriptional profile that reduces their ability to activate antigen presenting cells
    • Patakas A, et al. Abatacept inhibits T cell priming by inducing of a unique transcriptional profile that reduces their ability to activate antigen presenting cells. Arthritis Rheumatol. 2016;68(3):627-638.
    • (2016) Arthritis Rheumatol , vol.68 , Issue.3 , pp. 627-638
    • Patakas, A.1
  • 53
    • 84355162283 scopus 로고    scopus 로고
    • Canonical and non-canonical autophagy: Variations on a common theme of self-eating?
    • Codogno P, Mehrpour M, Proikas-Cezanne T. Canonical and non-canonical autophagy: variations on a common theme of self-eating? Nat Rev Mol Cell Biol. 2011;13(1):7-12.
    • (2011) Nat Rev Mol Cell Biol , vol.13 , Issue.1 , pp. 7-12
    • Codogno, P.1    Mehrpour, M.2    Proikas-Cezanne, T.3
  • 54
    • 67651241484 scopus 로고    scopus 로고
    • Abatacept does not induce direct gene expression changes in antigen-presenting cells
    • Carman JA, et al. Abatacept does not induce direct gene expression changes in antigen-presenting cells. J Clin Immunol. 2009;29(4):479-489.
    • (2009) J Clin Immunol , vol.29 , Issue.4 , pp. 479-489
    • Carman, J.A.1
  • 55
    • 84870953354 scopus 로고    scopus 로고
    • FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway
    • Zhou J, et al. FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway. Autophagy. 2012;8(12):1712-1723.
    • (2012) Autophagy , vol.8 , Issue.12 , pp. 1712-1723
    • Zhou, J.1
  • 56
    • 70350500068 scopus 로고    scopus 로고
    • FoxO transcription factors promote autophagy in cardiomyocytes
    • Sengupta A, Molkentin JD, Yutzey KE. FoxO transcription factors promote autophagy in cardiomyocytes. J Biol Chem. 2009;284(41):28319-28331.
    • (2009) J Biol Chem , vol.284 , Issue.41 , pp. 28319-28331
    • Sengupta, A.1    Molkentin, J.D.2    Yutzey, K.E.3
  • 57
    • 65249155463 scopus 로고    scopus 로고
    • Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells
    • Dejean AS, et al. Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells. Nat Immunol. 2009;10(5):504-513.
    • (2009) Nat Immunol , vol.10 , Issue.5 , pp. 504-513
    • Dejean, A.S.1
  • 58
    • 7244231007 scopus 로고    scopus 로고
    • CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice
    • Fallarino F, et al. CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice. J Exp Med. 2004;200(8):1051-1062.
    • (2004) J Exp Med , vol.200 , Issue.8 , pp. 1051-1062
    • Fallarino, F.1
  • 59
    • 0033522897 scopus 로고    scopus 로고
    • Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway
    • Nakae J, Park BC, Accili D. Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway. J Biol Chem. 1999;274(23):15982-15985.
    • (1999) J Biol Chem , vol.274 , Issue.23 , pp. 15982-15985
    • Nakae, J.1    Park, B.C.2    Accili, D.3
  • 60
    • 84962300957 scopus 로고    scopus 로고
    • FoxO1-mediated autophagy is required for NK cell development and innate immunity
    • Wang S, et al. FoxO1-mediated autophagy is required for NK cell development and innate immunity. Nat Commun. 2016;7:11023.
    • (2016) Nat Commun , vol.7 , pp. 11023
    • Wang, S.1
  • 61
    • 84856580998 scopus 로고    scopus 로고
    • Crucial role of granulocytic myeloid-derived suppressor cells in the regulation of central nervous system autoimmune disease
    • Ioannou M, et al. Crucial role of granulocytic myeloid-derived suppressor cells in the regulation of central nervous system autoimmune disease. J Immunol. 2012;188(3):1136-1146.
    • (2012) J Immunol , vol.188 , Issue.3 , pp. 1136-1146
    • Ioannou, M.1
  • 62
    • 0033012030 scopus 로고    scopus 로고
    • An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
    • Lutz MB, et al. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods. 1999;223(1):77-92.
    • (1999) J Immunol Methods , vol.223 , Issue.1 , pp. 77-92
    • Lutz, M.B.1
  • 63
    • 0023945481 scopus 로고
    • The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
    • Arnett FC, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988;31(3):315-324.
    • (1988) Arthritis Rheum , vol.31 , Issue.3 , pp. 315-324
    • Arnett, F.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.