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Volumn 119, Issue 1, 2018, Pages 455-467

The Role of Epigenetic Regulation and Pluripotency-Related MicroRNAs in Differentiation of Pancreatic Stem Cells to Beta Cells

Author keywords

BETA CELL; DIFFERENTIATION; HISTONE DEACETYLASES; microRNAs; PANCREATIC ISLET DERIVED MESENCHYMAL STEM CELLS; PLURIPOTENCY

Indexed keywords

BCL6 COREPRESSOR LIKE 1 PROTEIN; BROMODOMAIN CONTAINING PROTEIN 4; GLUCOSE; GLUCOSE TRANSPORTER 2; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 3; INSULIN; MICRORNA; MICRORNA 124; MICRORNA 146A; MICRORNA 146A 5P; MICRORNA 184; MICRORNA 18A; MICRORNA 18A 5P; MICRORNA 19B 5P; MICRORNA 30D 3P; MICRORNA 335; MICRORNA 433 5P; MICRORNA19B 5P; MYC PROTEIN; NEUROGENIN 3; ORGANIC CATION TRANSPORTER 3; PROTEIN BCL 2; PROTEIN BCL 6; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR PAX4; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG; VALPROIC ACID;

EID: 85021627704     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.26203     Document Type: Article
Times cited : (24)

References (48)
  • 1
    • 84904405914 scopus 로고    scopus 로고
    • Induction of neurotrophic and differentiation factors in neural stem cells by valproic acid
    • Almutawaa W, Kang NH, Pan Y, Niles LP. 2014. Induction of neurotrophic and differentiation factors in neural stem cells by valproic acid. Basic Clin Pharmacol Toxicol 115:216–221.
    • (2014) Basic Clin Pharmacol Toxicol , vol.115 , pp. 216-221
    • Almutawaa, W.1    Kang, N.H.2    Pan, Y.3    Niles, L.P.4
  • 2
    • 0028817069 scopus 로고
    • Regulation and function of Bcl-2 during differentiation-induced cell death in HL-60 promyelocytic cells
    • Benito A, Grillot D, Nuñez G, Fernández-Luna JL. 1995. Regulation and function of Bcl-2 during differentiation-induced cell death in HL-60 promyelocytic cells. Am J Pathol 146:481–490.
    • (1995) Am J Pathol , vol.146 , pp. 481-490
    • Benito, A.1    Grillot, D.2    Nuñez, G.3    Fernández-Luna, J.L.4
  • 3
    • 84878795484 scopus 로고    scopus 로고
    • Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology
    • Bernhard F, Landgraf K, Klöting N, Berthold A, Büttner P, Friebe D. 2013. Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology. Diabetologia 56:311–322.
    • (2013) Diabetologia , vol.56 , pp. 311-322
    • Bernhard, F.1    Landgraf, K.2    Klöting, N.3    Berthold, A.4    Büttner, P.5    Friebe, D.6
  • 4
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ. 2006. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125:315–326.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3    Kamal, M.4    Huebert, D.J.5
  • 5
    • 79951485439 scopus 로고    scopus 로고
    • Comprehensive expression analysis of prostanoid enzymes and receptors in the human endometrium across the menstrual cycle
    • Catalano RD, Wilson MR, Boddy SC, Jabbour HN. 2011. Comprehensive expression analysis of prostanoid enzymes and receptors in the human endometrium across the menstrual cycle. Mol Hum Reprod 17:182–192.
    • (2011) Mol Hum Reprod , vol.17 , pp. 182-192
    • Catalano, R.D.1    Wilson, M.R.2    Boddy, S.C.3    Jabbour, H.N.4
  • 8
    • 77956592608 scopus 로고    scopus 로고
    • Kctd15 inhibits neural crest formation by attenuating Wnt/beta-catenin signaling output
    • Dutta S, Dawid IB. 2010. Kctd15 inhibits neural crest formation by attenuating Wnt/beta-catenin signaling output. Development 137:3013–3018.
    • (2010) Development , vol.137 , pp. 3013-3018
    • Dutta, S.1    Dawid, I.B.2
  • 9
    • 79959805164 scopus 로고    scopus 로고
    • miRWalk–database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes
    • Dweep H, Sticht C, Pandey P, Gretz N. 2011. miRWalk–database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes. J Biomed Inform 44:839–847.
    • (2011) J Biomed Inform , vol.44 , pp. 839-847
    • Dweep, H.1    Sticht, C.2    Pandey, P.3    Gretz, N.4
  • 10
    • 0037015670 scopus 로고    scopus 로고
    • BTG2(TIS21/PC3) induces neuronal differentiation and prevents apoptosis of terminally differentiated PC12 cells
    • el-Ghissassi F, Valsesia-Wittmann S, Falette N, Duriez C, Walden PD, Puisieux A. 2002. BTG2(TIS21/PC3) induces neuronal differentiation and prevents apoptosis of terminally differentiated PC12 cells. Oncogene 21:6772–6778.
    • (2002) Oncogene , vol.21 , pp. 6772-6778
    • el-Ghissassi, F.1    Valsesia-Wittmann, S.2    Falette, N.3    Duriez, C.4    Walden, P.D.5    Puisieux, A.6
  • 11
    • 84859140033 scopus 로고    scopus 로고
    • Pax6 is crucial for beta cell function, insulin biosynthesis, and glucose-induced insulin secretion
    • Gosmain Y, Katz LS, Masson MH, Cheyssac C, Poisson C, Philippe J. 2012. Pax6 is crucial for beta cell function, insulin biosynthesis, and glucose-induced insulin secretion. Mol Endocrinol 26:696–709.
    • (2012) Mol Endocrinol , vol.26 , pp. 696-709
    • Gosmain, Y.1    Katz, L.S.2    Masson, M.H.3    Cheyssac, C.4    Poisson, C.5    Philippe, J.6
  • 12
    • 53549088061 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors
    • Haumaitre C, Lenoir O, Scharfmann R. 2008. Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors. Mol Cell Biol 28:6373–6383.
    • (2008) Mol Cell Biol , vol.28 , pp. 6373-6383
    • Haumaitre, C.1    Lenoir, O.2    Scharfmann, R.3
  • 13
    • 0023944405 scopus 로고
    • A transient increase in histone H2A ubiquitination is coincident with the onset of erythroleukemic cell differentiation
    • Hensold JO, Swerdlow PS, Housman DE. 1988. A transient increase in histone H2A ubiquitination is coincident with the onset of erythroleukemic cell differentiation. Blood 71:1153–1156.
    • (1988) Blood , vol.71 , pp. 1153-1156
    • Hensold, J.O.1    Swerdlow, P.S.2    Housman, D.E.3
  • 15
    • 46949085597 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
    • Huangfu D, Maehr R, Guo D. 2008. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol 26:795–797.
    • (2008) Nat Biotechnol , vol.26 , pp. 795-797
    • Huangfu, D.1    Maehr, R.2    Guo, D.3
  • 16
    • 84881125893 scopus 로고    scopus 로고
    • B-cell translocation gene 2 positively regulates GLP-1-stimulated insulin secretion via induction of PDX-1 in pancreatic beta cells
    • Hwang SL, Kwon O, Kim SG, Lee IK, Kim YD. 2013. B-cell translocation gene 2 positively regulates GLP-1-stimulated insulin secretion via induction of PDX-1 in pancreatic beta cells. Exp Mol Med 45:e25.
    • (2013) Exp Mol Med , vol.45
    • Hwang, S.L.1    Kwon, O.2    Kim, S.G.3    Lee, I.K.4    Kim, Y.D.5
  • 17
    • 84903367135 scopus 로고    scopus 로고
    • Translational regulation of NeuroD1 expression by FMRP: Involvement in glutamatergic neuronal differentiation of cultured rat primary neural progenitor cells
    • Jeon SJ, Kim JW, Kim KC, Han SM, Go HS, Seo JE, Choi CS, Ryu JH, Shin CY, Song MR. 2014. Translational regulation of NeuroD1 expression by FMRP: Involvement in glutamatergic neuronal differentiation of cultured rat primary neural progenitor cells. Cell Mol Neurobiol 34:297–305.
    • (2014) Cell Mol Neurobiol , vol.34 , pp. 297-305
    • Jeon, S.J.1    Kim, J.W.2    Kim, K.C.3    Han, S.M.4    Go, H.S.5    Seo, J.E.6    Choi, C.S.7    Ryu, J.H.8    Shin, C.Y.9    Song, M.R.10
  • 18
    • 35848945091 scopus 로고    scopus 로고
    • MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3
    • Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA. 2007. MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol 311:603–612.
    • (2007) Dev Biol , vol.311 , pp. 603-612
    • Joglekar, M.V.1    Parekh, V.S.2    Mehta, S.3    Bhonde, R.R.4    Hardikar, A.A.5
  • 20
    • 77950563080 scopus 로고    scopus 로고
    • Isolation and characterization of stem cells from pancreatic islet: Pluripotency, differentiation potential and ultrastructural characteristics
    • Karaoz E, Ayhan S, Gacar G, Aksoy A, Duruksu G, Okçu A, Demircan PC, Sariboyaci AE, Kaymaz F, Kasap M. 2010. Isolation and characterization of stem cells from pancreatic islet: Pluripotency, differentiation potential and ultrastructural characteristics. Cytotherapy 12:288–302.
    • (2010) Cytotherapy , vol.12 , pp. 288-302
    • Karaoz, E.1    Ayhan, S.2    Gacar, G.3    Aksoy, A.4    Duruksu, G.5    Okçu, A.6    Demircan, P.C.7    Sariboyaci, A.E.8    Kaymaz, F.9    Kasap, M.10
  • 21
    • 84862023342 scopus 로고    scopus 로고
    • Unique responses of stem cell-derived vascular endothelial and mesenchymal cells to high levels of glucose
    • Keats E, Khan ZA. 2012. Unique responses of stem cell-derived vascular endothelial and mesenchymal cells to high levels of glucose. PLoS ONE 7:e38752.
    • (2012) PLoS ONE , vol.7
    • Keats, E.1    Khan, Z.A.2
  • 22
    • 84986879637 scopus 로고    scopus 로고
    • Glucose homeostasis by increasing beta-cell proliferation, function, and reducing its apoptosis through HDAC inhibition in juvenile diabetic rat
    • Khan S, Jena G. 2016. Glucose homeostasis by increasing beta-cell proliferation, function, and reducing its apoptosis through HDAC inhibition in juvenile diabetic rat. J Biochem Mol Toxicol 30:438–446.
    • (2016) J Biochem Mol Toxicol , vol.30 , pp. 438-446
    • Khan, S.1    Jena, G.2
  • 25
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. 2005. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120:15–20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 26
    • 85034708428 scopus 로고    scopus 로고
    • Sumoylation regulates multiple transcription factors to control lens differentiation
    • Li D, Gong L, Ji W, Deng M, Liu J, Chen P, Hu WF, Hu X. 2012. Sumoylation regulates multiple transcription factors to control lens differentiation. FASEB J 26:535.
    • (2012) FASEB J , vol.26 , pp. 535
    • Li, D.1    Gong, L.2    Ji, W.3    Deng, M.4    Liu, J.5    Chen, P.6    Hu, W.F.7    Hu, X.8
  • 30
    • 29844433852 scopus 로고    scopus 로고
    • A predominantly articular cartilage-associated gene, SCRG1, is induced by glucocorticoid and stimulates chondrogenesis in vitro
    • Ochi K, Derfoul A, Tuan RS. 2006. A predominantly articular cartilage-associated gene, SCRG1, is induced by glucocorticoid and stimulates chondrogenesis in vitro. Osteoarthritis Cartilage 14:30–38.
    • (2006) Osteoarthritis Cartilage , vol.14 , pp. 30-38
    • Ochi, K.1    Derfoul, A.2    Tuan, R.S.3
  • 32
    • 84859951800 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms
    • Paul PK, Bhatnagar S, Mishra V, Srivastava S, Darnay BG, Choi Y, Kumar A. 2012. The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms. Mol Cell Biol 32:1248–1259.
    • (2012) Mol Cell Biol , vol.32 , pp. 1248-1259
    • Paul, P.K.1    Bhatnagar, S.2    Mishra, V.3    Srivastava, S.4    Darnay, B.G.5    Choi, Y.6    Kumar, A.7
  • 35
    • 1842330860 scopus 로고    scopus 로고
    • Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development
    • Sander M, Neubuser A, Kalamaras J, Ee HC, Martin GR, German MS. 1997. Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. Genes Dev 11:1662–1673.
    • (1997) Genes Dev , vol.11 , pp. 1662-1673
    • Sander, M.1    Neubuser, A.2    Kalamaras, J.3    Ee, H.C.4    Martin, G.R.5    German, M.S.6
  • 36
    • 70349622815 scopus 로고    scopus 로고
    • The molecular mechanism of induced pluripotency: A two-switch
    • Scheper W, Copray S. 2009. The molecular mechanism of induced pluripotency: A two-switch. Stem Cell Rev 5:204–223.
    • (2009) Stem Cell Rev , vol.5 , pp. 204-223
    • Scheper, W.1    Copray, S.2
  • 37
    • 84892562030 scopus 로고    scopus 로고
    • USP3 counteracts RNF168 via deubiquitinating H2A and γH2AX at lysine 13 and 15
    • Sharma N, Zhu Q, Wani G, He J, Wang QE, Wani AA. 2014. USP3 counteracts RNF168 via deubiquitinating H2A and γH2AX at lysine 13 and 15. Cell Cycle 13:106–114.
    • (2014) Cell Cycle , vol.13 , pp. 106-114
    • Sharma, N.1    Zhu, Q.2    Wani, G.3    He, J.4    Wang, Q.E.5    Wani, A.A.6
  • 38
    • 84992310439 scopus 로고    scopus 로고
    • Epigenetic suppression of the antitumor cytotoxicity of NK cells by histone deacetylase inhibitor valproic acid
    • Shi X, Li M, Cui M, Niu C, Xu J, Zhou L, Li W, Gao Y, Kong W, Cui J, Hu J, Jin H. 2016. Epigenetic suppression of the antitumor cytotoxicity of NK cells by histone deacetylase inhibitor valproic acid. Am J Cancer Res 6:600–614.
    • (2016) Am J Cancer Res , vol.6 , pp. 600-614
    • Shi, X.1    Li, M.2    Cui, M.3    Niu, C.4    Xu, J.5    Zhou, L.6    Li, W.7    Gao, Y.8    Kong, W.9    Cui, J.10    Hu, J.11    Jin, H.12
  • 39
    • 84866262465 scopus 로고    scopus 로고
    • Suspension cultures of bone-marrow-derived mesenchymal stem cells: Effects of donor age and glucose level
    • Stolzing A, Bauer E, Scutt A. 2012. Suspension cultures of bone-marrow-derived mesenchymal stem cells: Effects of donor age and glucose level. Stem Cells Dev 21:2718–2723.
    • (2012) Stem Cells Dev , vol.21 , pp. 2718-2723
    • Stolzing, A.1    Bauer, E.2    Scutt, A.3
  • 40
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity
    • Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA, Reed JC. 1995. Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity. Cell 80:279–284.
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3    Kochel, K.4    Irie, S.5    Millan, J.A.6    Reed, J.C.7
  • 41
    • 84886375160 scopus 로고    scopus 로고
    • Role of PI3K-AKT-mTOR and wnt signaling pathways in transition of G1-S phase of cell cycle in cancer cells
    • Vadlakonda L, Pasupuleti M, Pallu R. 2013. Role of PI3K-AKT-mTOR and wnt signaling pathways in transition of G1-S phase of cell cycle in cancer cells. Front Oncol 12:85.
    • (2013) Front Oncol , vol.12 , pp. 85
    • Vadlakonda, L.1    Pasupuleti, M.2    Pallu, R.3
  • 45
    • 85006184635 scopus 로고    scopus 로고
    • The histone methyltransferase DOT1L: Regulatory functions and a cancer therapy target
    • Wong M, Polly P, Liu T. 2015. The histone methyltransferase DOT1L: Regulatory functions and a cancer therapy target. Am J Cancer Res 5:2823–2837.
    • (2015) Am J Cancer Res , vol.5 , pp. 2823-2837
    • Wong, M.1    Polly, P.2    Liu, T.3
  • 46
    • 84863585305 scopus 로고    scopus 로고
    • Nutritional regulation of genome-wide association obesity genes in a tissue-dependent manner
    • Yoganathan P, Karunakaran S, Ho MM, Clee SM. 2012. Nutritional regulation of genome-wide association obesity genes in a tissue-dependent manner. Nutr Metab (Lond) 9:65.
    • (2012) Nutr Metab (Lond) , vol.9 , pp. 65
    • Yoganathan, P.1    Karunakaran, S.2    Ho, M.M.3    Clee, S.M.4


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