-
1
-
-
79951847989
-
Principles and current strategies for targeting autophagy for cancer treatment
-
Amaravadi RK, Lippincott-Schwartz J, Yin XM, Weiss WA, Takebe N, Timmer W, DiPaola RS, Lotze MT, White E. 2011. Principles and current strategies for targeting autophagy for cancer treatment. Clin Cancer Res 17: 654-666
-
(2011)
Clin Cancer Res
, vol.17
, pp. 654-666
-
-
Amaravadi, R.K.1
Lippincott-Schwartz, J.2
Yin, X.M.3
Weiss, W.A.4
Takebe, N.5
Timmer, W.6
DiPaola, R.S.7
Lotze, M.T.8
White, E.9
-
2
-
-
84988905857
-
Recent insights into the function of autophagy in cancer
-
Amaravadi R, Kimmelman AC, White E. 2016. Recent insights into the function of autophagy in cancer. Genes Dev 30: 1913-1930
-
(2016)
Genes Dev
, vol.30
, pp. 1913-1930
-
-
Amaravadi, R.1
Kimmelman, A.C.2
White, E.3
-
3
-
-
0036729911
-
BAX and BAK mediate p53-independent suppression of tumorigenesis
-
Degenhardt K, Chen G, Lindsten T, White E. 2002. BAX and BAK mediate p53-independent suppression of tumorigenesis. Cancer Cell 2: 193-203
-
(2002)
Cancer Cell
, vol.2
, pp. 193-203
-
-
Degenhardt, K.1
Chen, G.2
Lindsten, T.3
White, E.4
-
4
-
-
79959952405
-
Liver autophagy contributes to the maintenance of blood glucose and amino acid levels
-
Ezaki J, Matsumoto N, Takeda-Ezaki M, Komatsu M, Takahashi K, Hiraoka Y, Taka H, Fujimura T, Takehana K, Yoshida M, et al. 2011. Liver autophagy contributes to the maintenance of blood glucose and amino acid levels. Autophagy 7: 727-736
-
(2011)
Autophagy
, vol.7
, pp. 727-736
-
-
Ezaki, J.1
Matsumoto, N.2
Takeda-Ezaki, M.3
Komatsu, M.4
Takahashi, K.5
Hiraoka, Y.6
Taka, H.7
Fujimura, T.8
Takehana, K.9
Yoshida, M.10
-
5
-
-
79952228407
-
Activated Ras requires autophagy to maintain oxidativemetabolismand tumorigenesis
-
Guo JY, Chen HY, Mathew R, Fan J, Strohecker AM, Karsli-Uzunbas G, Kamphorst JJ, Chen G, Lemons JM, Karantza V, et al. 2011. Activated Ras requires autophagy to maintain oxidativemetabolismand tumorigenesis. Genes Dev 25: 460-470
-
(2011)
Genes Dev
, vol.25
, pp. 460-470
-
-
Guo, J.Y.1
Chen, H.Y.2
Mathew, R.3
Fan, J.4
Strohecker, A.M.5
Karsli-Uzunbas, G.6
Kamphorst, J.J.7
Chen, G.8
Lemons, J.M.9
Karantza, V.10
-
6
-
-
84879777723
-
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
-
Guo JY, Karsli-Uzunbas G, Mathew R, Aisner SC, Kamphorst JJ, Strohecker AM, Chen G, Price S, Lu W, Teng X, et al. 2013. Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis. Genes Dev 27: 1447-1461
-
(2013)
Genes Dev
, vol.27
, pp. 1447-1461
-
-
Guo, J.Y.1
Karsli-Uzunbas, G.2
Mathew, R.3
Aisner, S.C.4
Kamphorst, J.J.5
Strohecker, A.M.6
Chen, G.7
Price, S.8
Lu, W.9
Teng, X.10
-
7
-
-
84983359562
-
Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
-
Guo JY, Teng X, Laddha SV, Ma S, Van Nostrand SC, Yang Y, Khor S, Chan CS, Rabinowitz JD, White E. 2016. Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells. Genes Dev 30: 1704-1717
-
(2016)
Genes Dev
, vol.30
, pp. 1704-1717
-
-
Guo, J.Y.1
Teng, X.2
Laddha, S.V.3
Ma, S.4
Van Nostrand, S.C.5
Yang, Y.6
Khor, S.7
Chan, C.S.8
Rabinowitz, J.D.9
White, E.10
-
8
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, Yokoyama M, Mishima K, Saito I, Okano H, et al. 2006. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441: 885-889
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
Yokoyama, M.7
Mishima, K.8
Saito, I.9
Okano, H.10
-
9
-
-
84947460214
-
The genomic landscape of renal oncocytoma identifies a metabolic barrier to tumorigenesis
-
Joshi S, Tolkunov D, Aviv H, Hakimi AA, Yao M, Hsieh JJ, Ganesan S, Chan CS, White E. 2015. The genomic landscape of renal oncocytoma identifies a metabolic barrier to tumorigenesis. Cell Rep 13: 1895-1908
-
(2015)
Cell Rep
, vol.13
, pp. 1895-1908
-
-
Joshi, S.1
Tolkunov, D.2
Aviv, H.3
Hakimi, A.A.4
Yao, M.5
Hsieh, J.J.6
Ganesan, S.7
Chan, C.S.8
White, E.9
-
10
-
-
84905497318
-
Autophagy is required for glucose homeostasis and lung tumor maintenance
-
Karsli-Uzunbas G, Guo JY, Price S, Teng X, Laddha SV, Khor S, Kalaany NY, Jacks T, Chan CS, Rabinowitz JD, et al. 2014. Autophagy is required for glucose homeostasis and lung tumor maintenance. Cancer Discov 4: 914-927
-
(2014)
Cancer Discov
, vol.4
, pp. 914-927
-
-
Karsli-Uzunbas, G.1
Guo, J.Y.2
Price, S.3
Teng, X.4
Laddha, S.V.5
Khor, S.6
Kalaany, N.Y.7
Jacks, T.8
Chan, C.S.9
Rabinowitz, J.D.10
-
11
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I, Ezaki J, Mizushima N, Ohsumi Y, Uchiyama Y, et al. 2005. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 169: 425-434
-
(2005)
J Cell Biol
, vol.169
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
Iwata, J.4
Murata, S.5
Tanida, I.6
Ezaki, J.7
Mizushima, N.8
Ohsumi, Y.9
Uchiyama, Y.10
-
12
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, Tanida I, Ueno T, Koike M, Uchiyama Y, Kominami E, et al. 2006. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 441: 880-884
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
Tanida, I.6
Ueno, T.7
Koike, M.8
Uchiyama, Y.9
Kominami, E.10
-
13
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T, Ohsumi Y, Tokuhisa T, Mizushima N. 2004. The role of autophagy during the early neonatal starvation period. Nature 432: 1032-1036
-
(2004)
Nature
, vol.432
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
Yamamoto, A.4
Nakaya, H.5
Yoshimori, T.6
Ohsumi, Y.7
Tokuhisa, T.8
Mizushima, N.9
-
14
-
-
85069238608
-
Starving cancer from the outside and inside: Separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors
-
Lashinger LM, O'Flanagan CH, Dunlap SM, Rasmussen AJ, Sweeney S, Guo JY, Lodi A, Tiziani S, White E, Hursting SD. 2016. Starving cancer from the outside and inside: Separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors. Cancer Metab 4: 18
-
(2016)
Cancer Metab
, vol.4
, pp. 18
-
-
Lashinger, L.M.1
O'Flanagan, C.H.2
Dunlap, S.M.3
Rasmussen, A.J.4
Sweeney, S.5
Guo, J.Y.6
Lodi, A.7
Tiziani, S.8
White, E.9
Hursting, S.D.10
-
15
-
-
66449099090
-
Autophagy suppresses tumorigenesis through elimination of p62
-
Mathew R, Karp CM, Beaudoin B, Vuong N, Chen G, Chen HY, Bray K, Reddy A, Bhanot G, Gelinas C, et al. 2009. Autophagy suppresses tumorigenesis through elimination of p62. Cell 137: 1062-1075
-
(2009)
Cell
, vol.137
, pp. 1062-1075
-
-
Mathew, R.1
Karp, C.M.2
Beaudoin, B.3
Vuong, N.4
Chen, G.5
Chen, H.Y.6
Bray, K.7
Reddy, A.8
Bhanot, G.9
Gelinas, C.10
-
16
-
-
84907994253
-
Functional role of autophagy-mediated proteome remodeling in cell survival signaling and innate immunity
-
Mathew R, Khor S, Hackett SR, Rabinowitz JD, Perlman DH, White E. 2014. Functional role of autophagy-mediated proteome remodeling in cell survival signaling and innate immunity. Mol Cell 55: 916-930
-
(2014)
Mol Cell
, vol.55
, pp. 916-930
-
-
Mathew, R.1
Khor, S.2
Hackett, S.R.3
Rabinowitz, J.D.4
Perlman, D.H.5
White, E.6
-
17
-
-
81055144784
-
Autophagy: Renovation of cells and tissues
-
Mizushima N, Komatsu M. 2011. Autophagy: Renovation of cells and tissues. Cell 147: 728-741
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
18
-
-
1542283812
-
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
-
Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. 2004. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 15: 1101-1111
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1101-1111
-
-
Mizushima, N.1
Yamamoto, A.2
Matsui, M.3
Yoshimori, T.4
Ohsumi, Y.5
-
19
-
-
84939787271
-
Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism
-
Perera RM, Stoykova S, Nicolay BN, Ross KN, Fitamant J, Boukhali M, Lengrand J, Deshpande V, Selig MK, Ferrone CR, et al. 2015. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature 524: 361-365
-
(2015)
Nature
, vol.524
, pp. 361-365
-
-
Perera, R.M.1
Stoykova, S.2
Nicolay, B.N.3
Ross, K.N.4
Fitamant, J.5
Boukhali, M.6
Lengrand, J.7
Deshpande, V.8
Selig, M.K.9
Ferrone, C.R.10
-
20
-
-
84984704073
-
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
-
Sousa CM, Biancur De, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, et al. 2016. Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature 536: 479-483
-
(2016)
Nature
, vol.536
, pp. 479-483
-
-
Sousa, C.M.1
Biancur, D.2
Wang, X.3
Halbrook, C.J.4
Sherman, M.H.5
Zhang, L.6
Kremer, D.7
Hwang, R.F.8
Witkiewicz, A.K.9
Ying, H.10
-
21
-
-
84885350394
-
Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors
-
Strohecker AM, Guo JY, Karsli-Uzunbas G, Price SM, Chen GJ, Mathew R, McMahon M, White E. 2013. Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors. Cancer Discov 3: 1272-1285
-
(2013)
Cancer Discov
, vol.3
, pp. 1272-1285
-
-
Strohecker, A.M.1
Guo, J.Y.2
Karsli-Uzunbas, G.3
Price, S.M.4
Chen, G.J.5
Mathew, R.6
McMahon, M.7
White, E.8
-
22
-
-
76149092853
-
Control of ATP homeostasis during the respiro-fermentative transition in yeast
-
Walther T, Novo M, Rossger K, Letisse F, Loret MO, Portais JC, Francois JM. 2010. Control of ATP homeostasis during the respiro-fermentative transition in yeast. Mol Syst Biol 6: 344
-
(2010)
Mol Syst Biol
, vol.6
, pp. 344
-
-
Walther, T.1
Novo, M.2
Rossger, K.3
Letisse, F.4
Loret, M.O.5
Portais, J.C.6
Francois, J.M.7
-
23
-
-
84940550513
-
Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A
-
Wong PM, Feng Y,Wang J, Shi R, Jiang X. 2015. Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. Nat Commun 6: 8048
-
(2015)
Nat Commun
, vol.6
, pp. 8048
-
-
Wong, P.M.1
Feng, Y.2
Wang, J.3
Shi, R.4
Jiang, X.5
-
24
-
-
79952229430
-
Pancreatic cancers require autophagy for tumor growth
-
Yang S, Wang X, Contino G, Liesa M, Sahin E, Ying H, Bause A, Li Y, Stommel JM, Dell'Antonio G, et al. 2011. Pancreatic cancers require autophagy for tumor growth. Genes Dev 25: 717-729
-
(2011)
Genes Dev
, vol.25
, pp. 717-729
-
-
Yang, S.1
Wang, X.2
Contino, G.3
Liesa, M.4
Sahin, E.5
Ying, H.6
Bause, A.7
Li, Y.8
Stommel, J.M.9
Dell'Antonio, G.10
|