Inference of the distribution of selection coefficients for new nonsynonymous mutations using large samples

Genetics

Volumn 206, Issue 1, 2017, Pages 345-361

  Kim, Bernard Y ^a   Huber, Christian D ^a   Lohmueller, Kirk E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Deleterious mutations; Diffusion theory; Population genetics; Site frequency spectrum

Indexed keywords

ARTICLE; DATA ANALYSIS SOFTWARE; DEMOGRAPHY; EVOLUTION; FREQUENCY; GENE MUTATION; GENETIC LINKAGE; HUMAN; POPULATION GENETICS; PRIORITY JOURNAL; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; WHOLE EXOME SEQUENCING; BIOLOGICAL MODEL; CAUCASIAN; DNA SEQUENCE; EXOME; GENETIC SELECTION; GENETICS; HIGH THROUGHPUT SEQUENCING; MOLECULAR EVOLUTION; MUTATION; REPRODUCTIVE FITNESS; SAMPLE SIZE;

EUROPEAN CONTINENTAL ANCESTRY GROUP; EVOLUTION, MOLECULAR; EXOME; GENETIC FITNESS; GENETICS, POPULATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MODELS, GENETIC; MUTATION; SAMPLE SIZE; SELECTION, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 85020727089     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.116.197145     Document Type: Article

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