No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans

Nature Genetics

Volumn 47, Issue 2, 2015, Pages 126-131

  Do, Ron ^a,b   Balick, Daniel ^a,c   Li, Heng ^a,b   Adzhubei, Ivan ^c   Sunyaev, Shamil ^a,c   Reich, David ^a,b,d  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFRICAN; ARTICLE; EUROPEAN; GENE CONVERSION; GENE MUTATION; HEREDITY; HOMO NEANDERTHALENSIS; HUMAN; MUTATION RATE; POPULATION GENETICS; PRIORITY JOURNAL; SIMULATION; WEST AFRICAN; AMINO ACID SUBSTITUTION; ANIMAL; BIOLOGICAL MODEL; BLACK PERSON; CAUCASIAN; COMPUTER SIMULATION; GENE FREQUENCY; GENETIC SELECTION; GENETIC VARIABILITY; GENETICS; HUMAN GENOME; MUTATION; PHYSIOLOGY;

AFRICAN CONTINENTAL ANCESTRY GROUP; AMINO ACID SUBSTITUTION; ANIMALS; COMPUTER SIMULATION; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENETIC VARIATION; GENETICS, POPULATION; GENOME, HUMAN; HUMANS; MODELS, GENETIC; MUTATION; NEANDERTHALS; SELECTION, GENETIC;

EID: 84926169268     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3186     Document Type: Article

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