Allergen-specific IgG antibody signaling through FcγRIIb promotes food tolerance

Journal of Allergy and Clinical Immunology

Volumn 141, Issue 1, 2018, Pages 189-201.e3

  Burton, Oliver T ^a,b   Tamayo, Jaciel M ^a,b   Stranks, Amanda J ^a,b   Koleoglou, Kyle J ^a   Oettgen, Hans C ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Fc RIIb; food allergy; IgG; Mast cell; oral immunotherapy; regulatory T cell; tolerance

Indexed keywords

FC RECEPTOR; FC RECEPTOR IIB; FOOD ALLERGEN; FORKHEAD TRANSCRIPTION FACTOR; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 3; INTERLEUKIN 4; ALLERGEN; CELL SURFACE RECEPTOR; FCGR2B PROTEIN, MOUSE; IL4RA PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ARTICLE; BASOPHIL; BONE MARROW DERIVED MAST CELL; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CORE TEMPERATURE; DESENSITIZATION; FLOW CYTOMETRY; FOOD ALLERGY; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; MAST CELL; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; TH2 CELL; ANIMAL; BAGG ALBINO MOUSE; DISEASE MODEL; DRUG EFFECT; EGG ALLERGY; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ALLERGENS; ANIMALS; DISEASE MODELS, ANIMAL; EGG HYPERSENSITIVITY; IMMUNE TOLERANCE; IMMUNOGLOBULIN G; MAST CELLS; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; RECEPTORS, CELL SURFACE; RECEPTORS, IGG; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TH2 CELLS;

EID: 85020414654     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2017.03.045     Document Type: Article

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