-
1
-
-
33847023140
-
Intermittent hypoxia furthers the rationale for hypoxiainducible factor-1 targeting
-
Dewhirst MW. Intermittent hypoxia furthers the rationale for hypoxiainducible factor-1 targeting. Cancer Res 2007;67:854-5.
-
(2007)
Cancer Res
, vol.67
, pp. 854-855
-
-
Dewhirst, M.W.1
-
3
-
-
34547124566
-
Hypoxia and adaptive landscapes in the evolution of carcinogenesis
-
Gillies RJ, Gatenby RA. Hypoxia and adaptive landscapes in the evolution of carcinogenesis. Cancer Metastasis Rev 2007;26:311-7.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 311-317
-
-
Gillies, R.J.1
Gatenby, R.A.2
-
4
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003; 3:721-32.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
5
-
-
76349095132
-
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
-
Semenza GL. Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene 2010;29:625-34.
-
(2010)
Oncogene
, vol.29
, pp. 625-634
-
-
Semenza, G.L.1
-
6
-
-
0029051439
-
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A 1995;92:5510-4.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
7
-
-
56449095636
-
Hypoxia-inducible factor-2a correlates to distant recurrence and poor outcome in invasive breast cancer
-
Helczynska K, Larsson AM, Holmquist Mengelbier L, Bridges E, Fredlund E, Borgquist S, et al. Hypoxia-inducible factor-2a correlates to distant recurrence and poor outcome in invasive breast cancer. Cancer Res 2008;68:9212-20.
-
(2008)
Cancer Res
, vol.68
, pp. 9212-9220
-
-
Helczynska, K.1
Larsson, A.M.2
Holmquist Mengelbier, L.3
Bridges, E.4
Fredlund, E.5
Borgquist, S.6
-
8
-
-
34249340478
-
Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer
-
Hiraga T, Kizaka-Kondoh S, Hirota K, Hiraoka M, Yoneda T. Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer. Cancer Res 2007;67:4157-63.
-
(2007)
Cancer Res
, vol.67
, pp. 4157-4163
-
-
Hiraga, T.1
Kizaka-Kondoh, S.2
Hirota, K.3
Hiraoka, M.4
Yoneda, T.5
-
9
-
-
23844461100
-
Evaluating hypoxia-inducible factor-1a as a cancer therapeutic target via inducible RNA interference in vivo
-
Li L, Lin X, Staver M, Shoemaker A, SemizarovD, Fesik SW, et al. Evaluating hypoxia-inducible factor-1a as a cancer therapeutic target via inducible RNA interference in vivo. Cancer Res 2005;65:7249-58.
-
(2005)
Cancer Res
, vol.65
, pp. 7249-7258
-
-
Li, L.1
Lin, X.2
Staver, M.3
Shoemaker, A.4
Semizarov, D.5
Fesik, S.W.6
-
10
-
-
33846652552
-
Hypoxia-inducible factor-1a is a key regulator of metastasis in a transgenic model of cancer initiation and progression
-
Liao D, Corle C, Seagroves TN, Johnson RS. Hypoxia-inducible factor-1a is a key regulator of metastasis in a transgenic model of cancer initiation and progression. Cancer Res 2007;67:563-72.
-
(2007)
Cancer Res
, vol.67
, pp. 563-572
-
-
Liao, D.1
Corle, C.2
Seagroves, T.N.3
Johnson, R.S.4
-
11
-
-
84860389759
-
HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs
-
Zhang H, Wong CC, Wei H, Gilkes DM, Korangath P, Chaturvedi P, et al. HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs. Oncogene 2012;31:1757-70.
-
(2012)
Oncogene
, vol.31
, pp. 1757-1770
-
-
Zhang, H.1
Wong, C.C.2
Wei, H.3
Gilkes, D.M.4
Korangath, P.5
Chaturvedi, P.6
-
12
-
-
80053645045
-
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
-
Wong CC, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, et al. Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Proc Natl Acad Sci U S A 2011;108: 16369-74.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 16369-16374
-
-
Wong, C.C.1
Gilkes, D.M.2
Zhang, H.3
Chen, J.4
Wei, H.5
Chaturvedi, P.6
-
13
-
-
0037443587
-
Levels of hypoxia-inducible factor-1a independently predict prognosis in patients with lymph node negative breast carcinoma
-
Bos R, van der Groep P, Greijer AE, Shvarts A, Meijer S, Pinedo HM, et al. Levels of hypoxia-inducible factor-1a independently predict prognosis in patients with lymph node negative breast carcinoma. Cancer 2003;97: 1573-81.
-
(2003)
Cancer
, vol.97
, pp. 1573-1581
-
-
Bos, R.1
Van Der Groep, P.2
Greijer, A.E.3
Shvarts, A.4
Meijer, S.5
Pinedo, H.M.6
-
14
-
-
0036278899
-
Overexpression of hypoxia-inducible factor 1a is associated with an unfavorable prognosis in lymph node-positive breast cancer
-
Schindl M, Schoppmann SF, Samonigg H, Hausmaninger H, Kwasny W, GnantM, et al. Overexpression of hypoxia-inducible factor 1a is associated with an unfavorable prognosis in lymph node-positive breast cancer. Clin Cancer Res 2002;8:1831-7.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1831-1837
-
-
Schindl, M.1
Schoppmann, S.F.2
Samonigg, H.3
Hausmaninger, H.4
Kwasny, W.5
Gnant, M.6
-
15
-
-
33748037026
-
Hypoxia-inducible factor-1a expression predicts a poor response to primary chemoendocrine therapy and disease-free survival in primary human breast cancer
-
Generali D, Berruti A, Brizzi MP, Campo L, Bonardi S, Wigfield S, et al. Hypoxia-inducible factor-1a expression predicts a poor response to primary chemoendocrine therapy and disease-free survival in primary human breast cancer. Clin Cancer Res 2006;12:4562-8.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4562-4568
-
-
Generali, D.1
Berruti, A.2
Brizzi, M.P.3
Campo, L.4
Bonardi, S.5
Wigfield, S.6
-
16
-
-
46949094778
-
Hypoxia-inducible factor 1a is closely linked to an aggressive phenotype in breast cancer
-
Yamamoto Y, Ibusuki M, Okumura Y, Kawasoe T, Kai K, Iyama K, et al. Hypoxia-inducible factor 1a is closely linked to an aggressive phenotype in breast cancer. Breast Cancer Res Treat 2008;110:465-75.
-
(2008)
Breast Cancer Res Treat
, vol.110
, pp. 465-475
-
-
Yamamoto, Y.1
Ibusuki, M.2
Okumura, Y.3
Kawasoe, T.4
Kai, K.5
Iyama, K.6
-
17
-
-
23244463512
-
Overexpression of hypoxia-inducible factor HIF-1a predicts early relapse in breast cancer: Retrospective study in a series of 745 patients
-
Dales JP, Garcia S, Meunier-Carpentier S, Andrac-Meyer L, Haddad O, Lavaut MN, et al. Overexpression of hypoxia-inducible factor HIF-1a predicts early relapse in breast cancer: retrospective study in a series of 745 patients. Int J Cancer 2005;116:734-9.
-
(2005)
Int J Cancer
, vol.116
, pp. 734-739
-
-
Dales, J.P.1
Garcia, S.2
Meunier-Carpentier, S.3
Andrac-Meyer, L.4
Haddad, O.5
Lavaut, M.N.6
-
18
-
-
84876250357
-
Hypoxiainducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts
-
Gilkes DM, Bajpai S, Chaturvedi P, Wirtz D, Semenza GL. Hypoxiainducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts. J Biol Chem 2013;288:10819-29.
-
(2013)
J Biol Chem
, vol.288
, pp. 10819-10829
-
-
Gilkes, D.M.1
Bajpai, S.2
Chaturvedi, P.3
Wirtz, D.4
Semenza, G.L.5
-
19
-
-
84877899680
-
Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis
-
Gilkes DM, Bajpai S, Wong CC, Chaturvedi P, Hubbi ME, Wirtz D, et al. Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis. Mol Cancer Res 2013;11:456-66.
-
(2013)
Mol Cancer Res
, vol.11
, pp. 456-466
-
-
Gilkes, D.M.1
Bajpai, S.2
Wong, C.C.3
Chaturvedi, P.4
Hubbi, M.E.5
Wirtz, D.6
-
20
-
-
84878619137
-
Collagen prolyl hydroxylases are essential for breast cancer metastasis
-
Gilkes DM, Chaturvedi P, Bajpai S, Wong CC, Wei H, Pitcairn S, et al. Collagen prolyl hydroxylases are essential for breast cancer metastasis. Cancer Res 2013;73:3285-96.
-
(2013)
Cancer Res
, vol.73
, pp. 3285-3296
-
-
Gilkes, D.M.1
Chaturvedi, P.2
Bajpai, S.3
Wong, C.C.4
Wei, H.5
Pitcairn, S.6
-
21
-
-
18844424325
-
Integrins control motile strategy through a Rho-cofilin pathway
-
Danen EH, van Rheenen J, FrankenW, Huveneers S, Sonneveld P, Jalink K, et al. Integrins control motile strategy through a Rho-cofilin pathway. J Cell Biol 2005;169:515-26.
-
(2005)
J Cell Biol
, vol.169
, pp. 515-526
-
-
Danen, E.H.1
Van Rheenen, J.2
Franken, W.3
Huveneers, S.4
Sonneveld, P.5
Jalink, K.6
-
22
-
-
0025818032
-
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
-
Vleminckx K, Vakaet LJr, Mareel M, Fiers W, van Roy F. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 1991;66:107-19.
-
(1991)
Cell
, vol.66
, pp. 107-119
-
-
Vleminckx, K.1
Vakaet, L.2
Mareel, M.3
Fiers, W.4
Van Roy, F.5
-
23
-
-
84901594345
-
Hypoxia and the extracellular matrix: Drivers of tumour metastasis
-
Gilkes DM, Semenza GL, Wirtz D. Hypoxia and the extracellular matrix: drivers of tumour metastasis. Nat Rev Cancer 2014;14:430-9.
-
(2014)
Nat Rev Cancer
, vol.14
, pp. 430-439
-
-
Gilkes, D.M.1
Semenza, G.L.2
Wirtz, D.3
-
25
-
-
84859949610
-
The extracellular matrix: A dynamic niche in cancer progression
-
Lu P, Weaver VM, Werb Z. The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol 2012;196:395-406.
-
(2012)
J Cell Biol
, vol.196
, pp. 395-406
-
-
Lu, P.1
Weaver, V.M.2
Werb, Z.3
-
27
-
-
0037145037
-
Integrins: Bidirectional, allosteric signaling machines
-
Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell 2002;110:673-87.
-
(2002)
Cell
, vol.110
, pp. 673-687
-
-
Hynes, R.O.1
-
28
-
-
72949119124
-
Integrins in cancer: Biological implications and therapeutic opportunities
-
Desgrosellier JS, Cheresh DA. Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer 2010;10:9-22.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 9-22
-
-
Desgrosellier, J.S.1
Cheresh, D.A.2
-
29
-
-
33845669072
-
Integrin signaling in epithelial cells
-
Gilcrease MZ. Integrin signaling in epithelial cells. Cancer Lett 2007;247: 1-25.
-
(2007)
Cancer Lett
, vol.247
, pp. 1-25
-
-
Gilcrease, M.Z.1
-
30
-
-
70349309435
-
Selective induction of integrin b1 by hypoxia-inducible factor: Implications for wound healing
-
Keely S, Glover LE, MacManus CF, Campbell EL, Scully MM, Furuta GT, et al. Selective induction of integrin b1 by hypoxia-inducible factor: implications for wound healing. FASEB J 2009;23: 1338-46.
-
(2009)
FASEB J
, vol.23
, pp. 1338-1346
-
-
Keely, S.1
Glover, L.E.2
MacManus, C.F.3
Campbell, E.L.4
Scully, M.M.5
Furuta, G.T.6
-
31
-
-
0033868485
-
Hypoxia induces differential expression of the integrin receptors alpha(vbeta3) and alpha(vbeta5) in cultured human endothelial cells
-
Walton HL, Corjay MH, Mohamed SN, Mousa SA, Santomenna LD, Reilly TM. Hypoxia induces differential expression of the integrin receptors alpha(vbeta3) and alpha(vbeta5) in cultured human endothelial cells. J Cell Biochem 2000;78:674-80.
-
(2000)
J Cell Biochem
, vol.78
, pp. 674-680
-
-
Walton, H.L.1
Corjay, M.H.2
Mohamed, S.N.3
Mousa, S.A.4
Santomenna, L.D.5
Reilly, T.M.6
-
33
-
-
3142752573
-
Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression
-
Kong T, Eltzschig HK, Karhausen J, Colgan SP, Shelley CS. Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression. Proc Natl Acad Sci U S A 2004;101: 10440-5.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10440-10445
-
-
Kong, T.1
Eltzschig, H.K.2
Karhausen, J.3
Colgan, S.P.4
Shelley, C.S.5
-
34
-
-
34548616504
-
Identification of Pura as a new hypoxia response factor responsible for coordinated induction of the b2 integrin family
-
Kong T, Scully M, Shelley CS, Colgan SP. Identification of Pura as a new hypoxia response factor responsible for coordinated induction of the b2 integrin family. J Immunol 2007;179:1934-41.
-
(2007)
J Immunol
, vol.179
, pp. 1934-1941
-
-
Kong, T.1
Scully, M.2
Shelley, C.S.3
Colgan, S.P.4
-
35
-
-
2542588628
-
Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates
-
Koike T, Kimura N, Miyazaki K, Yabuta T, Kumamoto K, Takenoshita S, et al. Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates. Proc Natl Acad Sci U S A 2004;101:8132-7.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8132-8137
-
-
Koike, T.1
Kimura, N.2
Miyazaki, K.3
Yabuta, T.4
Kumamoto, K.5
Takenoshita, S.6
-
36
-
-
84862875401
-
Increased stemness and migration of human mesenchymal stem cells in hypoxia is associated with altered integrin expression
-
Saller MM, Prall WC, Docheva D, Schonitzer V, Popov T, Anz D, et al. Increased stemness and migration of human mesenchymal stem cells in hypoxia is associated with altered integrin expression. Biochem Biophys Res Commun 2012;423:379-85.
-
(2012)
Biochem Biophys Res Commun
, vol.423
, pp. 379-385
-
-
Saller, M.M.1
Prall, W.C.2
Docheva, D.3
Schonitzer, V.4
Popov, T.5
Anz, D.6
-
37
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
The Cancer Genome Atlas Network
-
The Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 2012;490:61-70.
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
-
38
-
-
79952819724
-
GOBO: Gene expressionbased outcome for breast cancer online
-
RingnerM, Fredlund E, Hakkinen J, BorgA, Staaf J.GOBO: gene expressionbased outcome for breast cancer online. PLoS One 2011;6:e17911.
-
(2011)
PLoS One
, vol.6
, pp. e17911
-
-
Ringner, M.1
Fredlund, E.2
Hakkinen, J.3
Borg, A.4
Staaf, J.5
-
39
-
-
84860389759
-
HIF-1- dependent expression of angiopoietin-like 4 and L1CAMmediates vascular metastasis of hypoxic breast cancer cells to the lungs
-
Zhang H, Wong C, Wei H, Gilkes D, Korangath P, Chaturvedi P, et al. HIF-1- dependent expression of angiopoietin-like 4 and L1CAMmediates vascular metastasis of hypoxic breast cancer cells to the lungs. Oncogene 2011;31: 1757-70.
-
(2011)
Oncogene
, vol.31
, pp. 1757-1770
-
-
Zhang, H.1
Wong, C.2
Wei, H.3
Gilkes, D.4
Korangath, P.5
Chaturvedi, P.6
-
40
-
-
84910077247
-
Hypoxiainducible factors enhance glutamate signaling in cancer cells
-
Hu H, Takano N, Xiang L, Gilkes DM, Luo W, Semenza GL. Hypoxiainducible factors enhance glutamate signaling in cancer cells. Oncotarget 2014;5:8853-68.
-
(2014)
Oncotarget
, vol.5
, pp. 8853-8868
-
-
Hu, H.1
Takano, N.2
Xiang, L.3
Gilkes, D.M.4
Luo, W.5
Semenza, G.L.6
-
41
-
-
84923806486
-
Statistical analysis of cell migration in 3D using the anisotropic persistent random walk model
-
Wu PH, Giri A, Wirtz D. Statistical analysis of cell migration in 3D using the anisotropic persistent random walk model. Nat Protoc 2015;10: 517-27.
-
(2015)
Nat Protoc
, vol.10
, pp. 517-527
-
-
Wu, P.H.1
Giri, A.2
Wirtz, D.3
-
42
-
-
84952898161
-
Collective cancer cell invasion induced by coordinated contractile stresses
-
Jimenez Valencia AM, Wu PH, Yogurtcu ON, Rao P, DiGiacomo J, Godet I, et al. Collective cancer cell invasion induced by coordinated contractile stresses. Oncotarget 2015;6:43438-51.
-
(2015)
Oncotarget
, vol.6
, pp. 43438-43451
-
-
Jimenez Valencia, A.M.1
Wu, P.H.2
Yogurtcu, O.N.3
Rao, P.4
DiGiacomo, J.5
Godet, I.6
-
43
-
-
84918530536
-
Hypoxiainducible factors are required for chemotherapy resistance of breast cancer stem cells
-
Samanta D, Gilkes DM, Chaturvedi P, Xiang L, Semenza GL. Hypoxiainducible factors are required for chemotherapy resistance of breast cancer stem cells. Proc Natl Acad Sci U S A 2014;111:E5429-38.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E5429-E5438
-
-
Samanta, D.1
Gilkes, D.M.2
Chaturvedi, P.3
Xiang, L.4
Semenza, G.L.5
-
44
-
-
84875714704
-
Focal adhesion size uniquely predicts cell migration
-
Kim DH, Wirtz D. Focal adhesion size uniquely predicts cell migration. FASEB J 2013;27:1351-61.
-
(2013)
FASEB J
, vol.27
, pp. 1351-1361
-
-
Kim, D.H.1
Wirtz, D.2
-
45
-
-
84878890498
-
Predicting how cells spread andmigrate: Focal adhesion size does matter
-
Kim DH, Wirtz D. Predicting how cells spread andmigrate: focal adhesion size does matter. Cell Adh Migr 2013;7:293-6.
-
(2013)
Cell Adh Migr
, vol.7
, pp. 293-296
-
-
Kim, D.H.1
Wirtz, D.2
-
46
-
-
84896538215
-
Three-dimensional cell migration does not follow a random walk
-
WuPH, Giri A, Sun SX, Wirtz D. Three-dimensional cell migration does not follow a random walk. Proc Natl Acad Sci U S A 2014;111:3949-54.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 3949-3954
-
-
Wu, P.H.1
Giri, A.2
Sun, S.X.3
Wirtz, D.4
-
47
-
-
84898766031
-
Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters
-
Naba A, Clauser KR, Lamar JM, Carr SA, Hynes RO. Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters. eLife 2014;3:e01308.
-
(2014)
ELife
, vol.3
, pp. e01308
-
-
Naba, A.1
Clauser, K.R.2
Lamar, J.M.3
Carr, S.A.4
Hynes, R.O.5
-
48
-
-
79952747743
-
Aligned collagen is a prognostic signature for survival in human breast carcinoma
-
ConklinMW, Eickhoff JC, Riching KM, Pehlke CA, Eliceiri KW, Provenzano PP, et al. Aligned collagen is a prognostic signature for survival in human breast carcinoma. Am J Pathol 2011;178:1221-32.
-
(2011)
Am J Pathol
, vol.178
, pp. 1221-1232
-
-
Conklin, M.W.1
Eickhoff, J.C.2
Riching, K.M.3
Pehlke, C.A.4
Eliceiri, K.W.5
Provenzano, P.P.6
-
49
-
-
80052499480
-
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2
-
Lyons TR, O'Brien J, Borges VF, Conklin MW, Keely PJ, Eliceiri KW, et al. Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. Nat Med 2011;17: 1109-15.
-
(2011)
Nat Med
, vol.17
, pp. 1109-1115
-
-
Lyons, T.R.1
O'Brien, J.2
Borges, V.F.3
Conklin, M.W.4
Keely, P.J.5
Eliceiri, K.W.6
-
50
-
-
84863862833
-
Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression
-
Schedin P, Keely PJ. Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression. Cold Spring Harb Perspect Biol 2011;3:a003228.
-
(2011)
Cold Spring Harb Perspect Biol
, vol.3
, pp. a003228
-
-
Schedin, P.1
Keely, P.J.2
-
51
-
-
84884412852
-
Fibronectin expression in carcinoma cells correlates with tumor aggressiveness and poor clinical outcome in patients with invasive breast cancer
-
Bae YK, Kim A, Kim MK, Choi JE, Kang SH, Lee SJ. Fibronectin expression in carcinoma cells correlates with tumor aggressiveness and poor clinical outcome in patients with invasive breast cancer. Hum Pathol 2013;44: 2028-37.
-
(2013)
Hum Pathol
, vol.44
, pp. 2028-2037
-
-
Bae, Y.K.1
Kim, A.2
Kim, M.K.3
Choi, J.E.4
Kang, S.H.5
Lee, S.J.6
-
52
-
-
33646365644
-
Lysyl oxidase is essential for hypoxia-induced metastasis
-
Erler JT, Bennewith KL, Nicolau M, Dornhofer N, Kong C, Le QT, et al. Lysyl oxidase is essential for hypoxia-induced metastasis. Nature 2006;440: 1222-6.
-
(2006)
Nature
, vol.440
, pp. 1222-1226
-
-
Erler, J.T.1
Bennewith, K.L.2
Nicolau, M.3
Dornhofer, N.4
Kong, C.5
Le, Q.T.6
-
53
-
-
84865149277
-
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
-
Wong CC, Zhang H, Gilkes DM, Chen J, Wei H, Chaturvedi P, et al. Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis. J Mol Med 2012;90: 803-15.
-
(2012)
J Mol Med
, vol.90
, pp. 803-815
-
-
Wong, C.C.1
Zhang, H.2
Gilkes, D.M.3
Chen, J.4
Wei, H.5
Chaturvedi, P.6
-
54
-
-
84875445066
-
LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis
-
Cox TR, Bird D, Baker AM, Barker HE, Ho MW, Lang G, et al. LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis. Cancer Res 2013;73:1721-32.
-
(2013)
Cancer Res
, vol.73
, pp. 1721-1732
-
-
Cox, T.R.1
Bird, D.2
Baker, A.M.3
Barker, H.E.4
Ho, M.W.5
Lang, G.6
-
55
-
-
57849100048
-
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
-
Erler JT, Bennewith KL, Cox TR, Lang G, Bird D, Koong A, et al. Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell 2009; 15:35-44.
-
(2009)
Cancer Cell
, vol.15
, pp. 35-44
-
-
Erler, J.T.1
Bennewith, K.L.2
Cox, T.R.3
Lang, G.4
Bird, D.5
Koong, A.6
-
56
-
-
80053645045
-
Hypoxia-inducible factor 1 is amaster regulator of breast cancer metastatic niche formation
-
Wong CC-L, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, et al. Hypoxia-inducible factor 1 is amaster regulator of breast cancer metastatic niche formation. Proc Natl Acad Sci U S A 2011;108:16369-74.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 16369-16374
-
-
Cc-L, W.1
Gilkes, D.M.2
Zhang, H.3
Chen, J.4
Wei, H.5
Chaturvedi, P.6
-
57
-
-
84885161391
-
The Arp2/ 3 complex mediates multigeneration dendritic protrusions for efficient 3- dimensional cancer cell migration
-
Giri A, Bajpai S, Trenton N, Jayatilaka H, Longmore GD, Wirtz D. The Arp2/ 3 complex mediates multigeneration dendritic protrusions for efficient 3- dimensional cancer cell migration. FASEB J 2013;27:4089-99.
-
(2013)
FASEB J
, vol.27
, pp. 4089-4099
-
-
Giri, A.1
Bajpai, S.2
Trenton, N.3
Jayatilaka, H.4
Longmore, G.D.5
Wirtz, D.6
-
58
-
-
84949861346
-
A5b1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3
-
Paul NR, Allen JL, Chapman A, Morlan-Mairal M, Zindy E, Jacquemet G, et al. a5b1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3. J Cell Biol 2015;210:1013-31.
-
(2015)
J Cell Biol
, vol.210
, pp. 1013-1031
-
-
Paul, N.R.1
Allen, J.L.2
Chapman, A.3
Morlan-Mairal, M.4
Zindy, E.5
Jacquemet, G.6
-
59
-
-
84892930021
-
Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells
-
Gilkes DM, Xiang L, Lee SJ, Chaturvedi P, Hubbi ME, Wirtz D, et al. Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells. Proc Natl Acad Sci U S A 2014;111: E384-E93.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E384-E393
-
-
Gilkes, D.M.1
Xiang, L.2
Lee, S.J.3
Chaturvedi, P.4
Hubbi, M.E.5
Wirtz, D.6
-
60
-
-
84908563697
-
Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): A multicentre, randomised, open-label, phase 3 trial
-
Stupp R, Hegi ME, Gorlia T, Erridge SC, Perry J, Hong YK, et al. Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol 2014;15:1100-8.
-
(2014)
Lancet Oncol
, vol.15
, pp. 1100-1108
-
-
Stupp, R.1
Hegi, M.E.2
Gorlia, T.3
Erridge, S.C.4
Perry, J.5
Hong, Y.K.6
-
61
-
-
33645730359
-
ERBB2-mediated transcriptional up-regulation of the a5b1 integrin fibronectin receptor promotes tumor cell survival under adverse conditions
-
Spangenberg C, Lausch EU, Trost TM, Prawitt D, May A, Keppler R, et al. ERBB2-mediated transcriptional up-regulation of the a5b1 integrin fibronectin receptor promotes tumor cell survival under adverse conditions. Cancer Res 2006;66:3715-25.
-
(2006)
Cancer Res
, vol.66
, pp. 3715-3725
-
-
Spangenberg, C.1
Lausch, E.U.2
Trost, T.M.3
Prawitt, D.4
May, A.5
Keppler, R.6
-
62
-
-
84900420642
-
Oncogenic targeting of BRM drives malignancy through C/EBPb-dependent induction of a5 integrin
-
Damiano L, Stewart KM, Cohet N, Mouw JK, Lakins JN, Debnath J, et al. Oncogenic targeting of BRM drives malignancy through C/EBPb-dependent induction of a5 integrin. Oncogene 2014;33: 2441-53.
-
(2014)
Oncogene
, vol.33
, pp. 2441-2453
-
-
Damiano, L.1
Stewart, K.M.2
Cohet, N.3
Mouw, J.K.4
Lakins, J.N.5
Debnath, J.6
-
63
-
-
84985956979
-
MIR-214 and miR-148b targeting inhibits dissemination of melanoma and breast cancer
-
Orso F, Quirico L, Virga F, Penna E, Dettori D, Cimino D, et al. miR-214 and miR-148b targeting inhibits dissemination of melanoma and breast cancer. Cancer Res 2016;76:5151-62.
-
(2016)
Cancer Res
, vol.76
, pp. 5151-5162
-
-
Orso, F.1
Quirico, L.2
Virga, F.3
Penna, E.4
Dettori, D.5
Cimino, D.6
-
64
-
-
33749577839
-
A non- RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo
-
Khalili P, Arakelian A, Chen G, Plunkett ML, Beck I, Parry GC, et al. A non- RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo. Mol Cancer Ther 2006;5:2271-80.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2271-2280
-
-
Khalili, P.1
Arakelian, A.2
Chen, G.3
Plunkett, M.L.4
Beck, I.5
Parry, G.C.6
-
65
-
-
0037457423
-
Inhibition of integrin a5b1 function with a small peptide (ATN161) plus continuous 5FU infusion reduces colorectal liver metastases and improves survival in mice
-
Stoeltzing O, Liu W, Reinmuth N, Fan F, Parry GC, Parikh AA, et al. Inhibition of integrin a5b1 function with a small peptide (ATN161) plus continuous 5FU infusion reduces colorectal liver metastases and improves survival in mice. Int J Cancer 2003;104:496-503.
-
(2003)
Int J Cancer
, vol.104
, pp. 496-503
-
-
Stoeltzing, O.1
Liu, W.2
Reinmuth, N.3
Fan, F.4
Parry, G.C.5
Parikh, A.A.6
-
66
-
-
0034650758
-
Antiinvasive, antitumorigenic, and antimetastatic activities of the PHSCN sequence in prostate carcinoma
-
Livant DL, Brabec RK, Pienta KJ, Allen DL, Kurachi K, Markwart S, et al. Antiinvasive, antitumorigenic, and antimetastatic activities of the PHSCN sequence in prostate carcinoma. Cancer Res 2000;60:309-20.
-
(2000)
Cancer Res
, vol.60
, pp. 309-320
-
-
Livant, D.L.1
Brabec, R.K.2
Pienta, K.J.3
Allen, D.L.4
Kurachi, K.5
Markwart, S.6
-
67
-
-
33745240059
-
Phase 1 trial of the antiangiogenic peptide ATN-161 (Ac-PHSCN-NH2), a beta integrin antagonist, in patients with solid tumours
-
Cianfrocca M, Kimmel K, Gallo J, Cardoso T, Brown M, Hudes G, et al. Phase 1 trial of the antiangiogenic peptide ATN-161 (Ac-PHSCN-NH2), a beta integrin antagonist, in patients with solid tumours. Br J Cancer 2006;94:1621-6.
-
(2006)
Br J Cancer
, vol.94
, pp. 1621-1626
-
-
Cianfrocca, M.1
Kimmel, K.2
Gallo, J.3
Cardoso, T.4
Brown, M.5
Hudes, G.6
-
68
-
-
82555189403
-
B1-integrin: A potential therapeutic target in the battle against cancer recurrence
-
Barkan D, Chambers AF. b1-integrin: a potential therapeutic target in the battle against cancer recurrence. Clin Cancer Res 2011;17:7219-23.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 7219-7223
-
-
Barkan, D.1
Chambers, A.F.2
-
69
-
-
84920450458
-
A laminin 511 matrix is regulated by TAZ and functions as the ligand for the a6Bb1 integrin to sustain breast cancer stem cells
-
Chang C, Goel HL, Gao H, Pursell B, Shultz LD, Greiner DL, et al. A laminin 511 matrix is regulated by TAZ and functions as the ligand for the a6Bb1 integrin to sustain breast cancer stem cells. Genes Dev 2015;29:1-6.
-
(2015)
Genes Dev
, vol.29
, pp. 1-6
-
-
Chang, C.1
Goel, H.L.2
Gao, H.3
Pursell, B.4
Shultz, L.D.5
Greiner, D.L.6
-
70
-
-
85003876125
-
Synthetic lethality in PTEN-mutant prostate cancer is induced by combinatorial PI3K/Akt and BCL-XL inhibition
-
Ren W, Joshi R, Mathew P. Synthetic lethality in PTEN-mutant prostate cancer is induced by combinatorial PI3K/Akt and BCL-XL inhibition. Mol Cancer Res 2016;14:1176-81.
-
(2016)
Mol Cancer Res
, vol.14
, pp. 1176-1181
-
-
Ren, W.1
Joshi, R.2
Mathew, P.3
|