메뉴 건너뛰기




Volumn 27, Issue 10, 2013, Pages 4089-4099

The Arp2/3 complex mediates multigeneration dendritic protrusions for efficient 3-dimensional cancer cell migration

Author keywords

3D environment; Collagen I matrix; Matrix deformation

Indexed keywords

ACTIN RELATED PROTEIN 2-3 COMPLEX; BLEBBISTATIN; CORTACTIN; CRK ASSOCIATED SUBSTRATE PROTEIN; FOCAL ADHESION KINASE; LATRUNCULIN B; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; PROTEIN; PROTEIN CDC42; TALIN; UNCLASSIFIED DRUG; WAVE1 PROTEIN; SMALL INTERFERING RNA;

EID: 84885161391     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-224352     Document Type: Article
Times cited : (61)

References (45)
  • 1
    • 0037459075 scopus 로고    scopus 로고
    • Cellular motility driven by assembly and disassembly of actin filaments
    • Pollard, T. D., and Borisy, G. G. (2003) Cellular motility driven by assembly and disassembly of actin filaments. Cell 112, 453-465
    • (2003) Cell , vol.112 , pp. 453-465
    • Pollard, T.D.1    Borisy, G.G.2
  • 2
    • 33749037156 scopus 로고    scopus 로고
    • The ARP2/3 complex: An actin nucleator comes of age
    • Goley, E. D., and Welch, M. D. (2006) The ARP2/3 complex: an actin nucleator comes of age. Nat Rev. Mol. Cell Biol 7, 713-726
    • (2006) Nat Rev. Mol. Cell Biol , vol.7 , pp. 713-726
    • Goley, E.D.1    Welch, M.D.2
  • 3
    • 0027937223 scopus 로고
    • Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
    • Derry, J. M., Ochs, H. D., and Francke, U. (1994) Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell 78, 635-644
    • (1994) Cell , vol.78 , pp. 635-644
    • Derry, J.M.1    Ochs, H.D.2    Francke, U.3
  • 4
    • 0029815611 scopus 로고    scopus 로고
    • N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases
    • Miki, H., Miura, K., and Takenawa, T. (1996) N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases. EMBO J. 15, 5326-5335
    • (1996) EMBO J. , vol.15 , pp. 5326-5335
    • Miki, H.1    Miura, K.2    Takenawa, T.3
  • 5
    • 0034624753 scopus 로고    scopus 로고
    • Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
    • Kim, A. S., Kakalis, L. T., Abdul-Manan, N., Liu, G. A., and Rosen, M. K. (2000) Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. Nature 404, 151-158
    • (2000) Nature , vol.404 , pp. 151-158
    • Kim, A.S.1    Kakalis, L.T.2    Abdul-Manan, N.3    Liu, G.A.4    Rosen, M.K.5
  • 6
    • 84861926483 scopus 로고    scopus 로고
    • The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration
    • Suraneni, P., Rubinstein, B., Unruh, J. R., Durnin, M., and Li, R. (2012) The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration. J. Cell Biol. 197, 239-251
    • (2012) J. Cell Biol. , vol.197 , pp. 239-251
    • Suraneni, P.1    Rubinstein, B.2    Unruh, J.R.3    Durnin, M.4    Li, R.5
  • 7
    • 84863229890 scopus 로고    scopus 로고
    • Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis
    • Wu, C., Asokan, S. B., Berginski, M. E., Haynes, E. M., Griffith, J. D., Gomez, S. M., and Bear, J. E. (2012) Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis. Cell 148, 973-987
    • (2012) Cell , vol.148 , pp. 973-987
    • Wu, C.1    Asokan, S.B.2    Berginski, M.E.3    Haynes, E.M.4    Griffith, J.D.5    Gomez, S.M.6    Bear, J.E.7
  • 8
    • 79959636906 scopus 로고    scopus 로고
    • The physics of cancer: The role of physical interactions and mechanical forces in metastasis
    • Wirtz, D., Konstantopoulos, K., and Searson, P. C. (2011) The physics of cancer: the role of physical interactions and mechanical forces in metastasis. Nat. Rev. Cancer 11, 512-522
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 512-522
    • Wirtz, D.1    Konstantopoulos, K.2    Searson, P.C.3
  • 9
    • 84872806319 scopus 로고    scopus 로고
    • Dimensional control of cancer cell migration
    • Konstantopoulos, K., Wu, P. H., and Wirtz, D. (2013) Dimensional control of cancer cell migration. Biophys. J. 104, 279-280
    • (2013) Biophys. J. , vol.104 , pp. 279-280
    • Konstantopoulos, K.1    Wu, P.H.2    Wirtz, D.3
  • 10
    • 0037328762 scopus 로고    scopus 로고
    • Dendritic fibroblasts in three-dimensional collagen matrices
    • Grinnell, F., Ho, C. H., Tamariz, E., Lee, D. J., and Skuta, G. (2003) Dendritic fibroblasts in three-dimensional collagen matrices. Mol. Biol. Cell 14, 384-395
    • (2003) Mol. Biol. Cell , vol.14 , pp. 384-395
    • Grinnell, F.1    Ho, C.H.2    Tamariz, E.3    Lee, D.J.4    Skuta, G.5
  • 11
    • 34248395119 scopus 로고    scopus 로고
    • Microtubule function in fibroblast spreading is modulated according to the tension state of cell-matrix interactions
    • Rhee, S., Jiang, H., Ho, C. H., and Grinnell, F. (2007) Microtubule function in fibroblast spreading is modulated according to the tension state of cell-matrix interactions. Proc. Natl. Acad. Sci. U. S. A. 104, 5425-5430
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 5425-5430
    • Rhee, S.1    Jiang, H.2    Ho, C.H.3    Grinnell, F.4
  • 12
    • 77049108859 scopus 로고    scopus 로고
    • The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion
    • Li, A., Dawson, J. C., Forero-Vargas, M., Spence, H. J., Konig, I., Anderson, K., and Machesky, L. M. (2010) The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion. Curr. Biol. 20, 339-345
    • (2010) Curr. Biol. , vol.20 , pp. 339-345
    • Li, A.1    Dawson, J.C.2    Forero-Vargas, M.3    Spence, H.J.4    Konig, I.5    Anderson, K.6    Machesky, L.M.7
  • 13
    • 68549130679 scopus 로고    scopus 로고
    • Proteolytic interstitial cell migration: A five-step process
    • Friedl, P., and Wolf, K. (2009) Proteolytic interstitial cell migration: a five-step process. Cancer Metast. Rev. 28, 129-135
    • (2009) Cancer Metast. Rev. , vol.28 , pp. 129-135
    • Friedl, P.1    Wolf, K.2
  • 14
    • 0037455576 scopus 로고    scopus 로고
    • Compensation mechanism in tumor cell migration: Mesenchymal-amoeboid transition after blocking of pericellular proteolysis
    • Wolf, K., Mazo, I., Leung, H., Engelke, K., Deryugina, E. I., Strongin, A. Y., Brocker, E. B., and Friedl, P. (2003) Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J. Cell Biol. 160, 267-277
    • (2003) J. Cell Biol. , vol.160 , pp. 267-277
    • Wolf, K.1    Mazo, I.2    Leung, H.3    Engelke, K.4    Deryugina, E.I.5    Strongin, A.Y.6    Brocker, E.B.7    Friedl, P.8
  • 15
  • 17
    • 37249003725 scopus 로고    scopus 로고
    • Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells
    • Yang, C., Czech, L., Gerboth, S., Kojima, S. I., and Svitkina, T. (2007) Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells. PloS Biol. 5, 2624-2645
    • (2007) PloS Biol. , vol.5 , pp. 2624-2645
    • Yang, C.1    Czech, L.2    Gerboth, S.3    Kojima, S.I.4    Svitkina, T.5
  • 18
    • 34547569807 scopus 로고    scopus 로고
    • Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
    • Wolf, K., Wu, Y. I., Liu, Y., Geiger, J., Overall, C., Stack, M. S., and Friedl, P. (2007) Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat. Cell Biol. 9, 893-904
    • (2007) Nat. Cell Biol. , vol.9 , pp. 893-904
    • Wolf, K.1    Wu, Y.I.2    Liu, Y.3    Geiger, J.4    Overall, C.5    Stack, M.S.6    Friedl, P.7
  • 20
    • 65249155429 scopus 로고    scopus 로고
    • Proteasedependent versus-independent cancer cell invasion programs: Three-dimensional amoeboid movement revisited
    • Sabeh, F., Shimizu-Hirota, R., and Weiss, S. J. (2009) Proteasedependent versus-independent cancer cell invasion programs: three-dimensional amoeboid movement revisited. J. Cell Biol. 185, 11-19
    • (2009) J. Cell Biol. , vol.185 , pp. 11-19
    • Sabeh, F.1    Shimizu-Hirota, R.2    Weiss, S.J.3
  • 21
    • 0034683746 scopus 로고    scopus 로고
    • Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate
    • Rohatgi, R., Ho, H. Y., and Kirschner, M. W. (2000) Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate. J. Cell Biol. 150, 1299-1310
    • (2000) J. Cell Biol. , vol.150 , pp. 1299-1310
    • Rohatgi, R.1    Ho, H.Y.2    Kirschner, M.W.3
  • 22
    • 0033574722 scopus 로고    scopus 로고
    • The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
    • Rohatgi, R., Ma, L., Miki, H., Lopez, M., Takenawa, T., and Kirschner, M. W. (1999) The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell 97, 221-231
    • (1999) Cell , vol.97 , pp. 221-231
    • Rohatgi, R.1    Ma, L.2    Miki, H.3    Lopez, M.4    Takenawa, T.5    Kirschner, M.W.6
  • 23
    • 0032585538 scopus 로고    scopus 로고
    • Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex
    • Machesky, L. M., and Insall, R. H. (1998) Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex. Curr. Biol. 8, 1347-1356
    • (1998) Curr. Biol. , vol.8 , pp. 1347-1356
    • Machesky, L.M.1    Insall, R.H.2
  • 24
    • 55749097433 scopus 로고    scopus 로고
    • The Arp2/3 activators WAVE and WASP have distinct genetic interactions with Rac GTPases in Caenorhabditis elegans axon guidance
    • Shakir, M. A., Jiang, K., Struckhoff, E. C., Demarco, R. S., Sotot, M. C., and Lundquist, E. A. (2008) The Arp2/3 activators WAVE and WASP have distinct genetic interactions with Rac GTPases in Caenorhabditis elegans axon guidance. Genetics 179, 1957-1971
    • (2008) Genetics , vol.179 , pp. 1957-1971
    • Shakir, M.A.1    Jiang, K.2    Struckhoff, E.C.3    Demarco, R.S.4    Sotot, M.C.5    Lundquist, E.A.6
  • 25
    • 0027419589 scopus 로고
    • Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex
    • Wu, H., and Parsons, J. T. (1993) Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex. J. Cell Biol. 120, 1417-1426
    • (1993) J. Cell Biol. , vol.120 , pp. 1417-1426
    • Wu, H.1    Parsons, J.T.2
  • 28
    • 0035814938 scopus 로고    scopus 로고
    • Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation
    • Weaver, A. M., Karginov, A. V., Kinley, A. W., Weed, S. A., Parsons, J. T., and Cooper, J. A. (2001) Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation. Curr. Biol. 11, 370-374
    • (2001) Curr. Biol. , vol.11 , pp. 370-374
    • Weaver, A.M.1    Karginov, A.V.2    Kinley, A.W.3    Weed, S.A.4    Parsons, J.T.5    Cooper, J.A.6
  • 29
    • 84856700597 scopus 로고    scopus 로고
    • Cells assemble invadopodialike structures and invade into matrigel in a matrix metalloprotease dependent manner in the circular invasion assay
    • Yu, X., and Machesky, L. M. (2012) Cells assemble invadopodialike structures and invade into matrigel in a matrix metalloprotease dependent manner in the circular invasion assay. PLoS ONE 7, e30605
    • (2012) PLoS ONE , vol.7
    • Yu, X.1    Machesky, L.M.2
  • 30
    • 78650497754 scopus 로고    scopus 로고
    • Reply: Reducing background fluorescence reveals adhesions in 3D matrices
    • Fraley, S. I., Feng, Y., Wirtz, D., and Longmore, G. D. (2011) Reply: reducing background fluorescence reveals adhesions in 3D matrices. Nat. Cell Biol. 13, 5-7
    • (2011) Nat. Cell Biol. , vol.13 , pp. 5-7
    • Fraley, S.I.1    Feng, Y.2    Wirtz, D.3    Longmore, G.D.4
  • 31
    • 14044249373 scopus 로고    scopus 로고
    • Cortactin regulates cell migration through activation of N-WASP
    • Kowalski, J. R., Egile, C., Gil, S., Snapper, S. B., and Thomas, S. M. (2005) Cortactin regulates cell migration through activation of N-WASP. J. Cell Sci. 118, 79-87
    • (2005) J. Cell Sci. , vol.118 , pp. 79-87
    • Kowalski, J.R.1    Egile, C.2    Gil, S.3    Snapper, S.B.4    Thomas, S.M.5
  • 32
    • 0031042493 scopus 로고    scopus 로고
    • Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton
    • Tapon, N., and Hall, A. (1997) Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton. Curr. Opin. Cell Biol. 9, 86-92
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 86-92
    • Tapon, N.1    Hall, A.2
  • 33
    • 0035090317 scopus 로고    scopus 로고
    • Activation of Arp2/3 complexmediated actin polymerization by cortactin
    • Uruno, T., Liu, J., Zhang, P., Fan, Y., Li, R., Mueller, S. C., and Zhan, X. (2001) Activation of Arp2/3 complexmediated actin polymerization by cortactin. Nat. Cell Biol. 3, 259-266
    • (2001) Nat. Cell Biol. , vol.3 , pp. 259-266
    • Uruno, T.1    Liu, J.2    Zhang, P.3    Fan, Y.4    Li, R.5    Mueller, S.C.6    Zhan, X.7
  • 34
    • 0345146913 scopus 로고    scopus 로고
    • Formation of filopodia-like bundles in vitro from a dendritic network
    • Vignjevic, D., Yarar, D., Welch, M. D., Peloquin, J., and Borisy, G. G. (2003) Formation of filopodia-like bundles in vitro from a dendritic network. J. Cell Biol. 160, 951-962
    • (2003) J. Cell Biol. , vol.160 , pp. 951-962
    • Vignjevic, D.1    Yarar, D.2    Welch, M.D.3    Peloquin, J.4    Borisy, G.G.5
  • 36
    • 33947654947 scopus 로고    scopus 로고
    • Noninvasive assessment of collagen gel microstructure and mechanics using multiphoton microscopy
    • Raub, C. B., Suresh, V., Krasieva, T., Lyubovitsky, J., Putnam, A. J., Tromberg, B. J., and George, S. C. (2007) Noninvasive assessment of collagen gel microstructure and mechanics using multiphoton microscopy. Biophys. J. 92, 2212-2222
    • (2007) Biophys. J. , vol.92 , pp. 2212-2222
    • Raub, C.B.1    Suresh, V.2    Krasieva, T.3    Lyubovitsky, J.4    Putnam, A.J.5    Tromberg, B.J.6    George, S.C.7
  • 37
    • 0033813556 scopus 로고    scopus 로고
    • Assembly of type I collagen: Fusion of fibril subunits and the influence of fibril diameter on mechanical properties
    • Christiansen, D. L., Huang, E. K., and Silver, F. H. (2000) Assembly of type I collagen: fusion of fibril subunits and the influence of fibril diameter on mechanical properties. Matrix Biol. 19, 409-420
    • (2000) Matrix Biol. , vol.19 , pp. 409-420
    • Christiansen, D.L.1    Huang, E.K.2    Silver, F.H.3
  • 39
    • 3543114271 scopus 로고    scopus 로고
    • Foot and mouth: Podosomes, invadopodia and circular dorsal ruffles
    • Buccione, R., Orth, J. D., and McNiven, M. A. (2004) Foot and mouth: podosomes, invadopodia and circular dorsal ruffles. Nat. Rev. Mol. Cell Biol. 5, 647-657
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 647-657
    • Buccione, R.1    Orth, J.D.2    McNiven, M.A.3
  • 40
    • 68549107801 scopus 로고    scopus 로고
    • Invadopodia: Specialized tumor cell structures for the focal degradation of the extracellular matrix
    • Buccione, R., Caldieri, G., and Ayala, I. (2009) Invadopodia: specialized tumor cell structures for the focal degradation of the extracellular matrix. Cancer Metast. Rev. 28, 137-149
    • (2009) Cancer Metast. Rev. , vol.28 , pp. 137-149
    • Buccione, R.1    Caldieri, G.2    Ayala, I.3
  • 41
    • 34249320529 scopus 로고    scopus 로고
    • Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia
    • Clark, E. S., Whigham, A. S., Yarbrough, W. G., and Weaver, A. M. (2007) Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia. Cancer Res. 67, 4227-4235
    • (2007) Cancer Res. , vol.67 , pp. 4227-4235
    • Clark, E.S.1    Whigham, A.S.2    Yarbrough, W.G.3    Weaver, A.M.4
  • 43
    • 79959541003 scopus 로고    scopus 로고
    • The 'ins' and 'outs' of podosomes and invadopodia: Characteristics, formation and function
    • Murphy, D. A., and Courtneidge, S. A. (2011) The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function. Nat. Rev. Mol. Cell Biol. 12, 413-426
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 413-426
    • Murphy, D.A.1    Courtneidge, S.A.2
  • 45
    • 56049099030 scopus 로고    scopus 로고
    • Mapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking
    • Bloom, R. J., George, J. P., Celedon, A., Sun, S. X., and Wirtz, D. (2008) Mapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking. Biophys. J. 95, 4077-4088
    • (2008) Biophys. J. , vol.95 , pp. 4077-4088
    • Bloom, R.J.1    George, J.P.2    Celedon, A.3    Sun, S.X.4    Wirtz, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.