KCNE2 deletion impairs insulin secretion and causes type 2 diabetes mellitus

FASEB Journal

Volumn 31, Issue 6, 2017, Pages 2674-2685

  Lee, Soo Min ^a   Baik, Jasmine ^a   Nguyen, Dara ^a   Nguyen, Victoria ^a   Liu, Shiwei ^a   Hu, Zhaoyang ^b   Abbott, Geoffrey W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Kv1.5; Kv2.1; KCNQ1; Potassium channel

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR BETA; INSULIN RECEPTOR SUBSTRATE 1; POTASSIUM CHANNEL KCNE2; POTASSIUM CHANNEL KCNQ1; UNCLASSIFIED DRUG; KCNE2 PROTEIN, HUMAN; KCNE2 PROTEIN, MOUSE; POTASSIUM; VOLTAGE GATED POTASSIUM CHANNEL;

ADULT; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ELECTRIC ACTIVITY; ELECTRIC POTENTIAL; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE DELETION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INFLAMMATION; INSULIN RELEASE; MEMBRANE POTENTIAL; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; ANIMAL; ELECTROPHYSIOLOGY; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PANCREAS ISLET; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; SIGNAL TRANSDUCTION; TISSUE CULTURE TECHNIQUE;

ANIMALS; DIABETES MELLITUS, TYPE 2; ELECTROPHYSIOLOGICAL PHENOMENA; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INSULIN; ISLETS OF LANGERHANS; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; PATCH-CLAMP TECHNIQUES; POTASSIUM; POTASSIUM CHANNELS, VOLTAGE-GATED; SIGNAL TRANSDUCTION; TISSUE CULTURE TECHNIQUES;

EID: 85020300322     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.201601347     Document Type: Article

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