-
1
-
-
0029952101
-
Ks cardiac potassium current
-
Barhanin, J. et al. KVLQT1 and lsK (minK) proteins associate to form the IKs cardiac potassium current. Nature 384, 78-80 (1996).
-
(1996)
Nature
, vol.384
, pp. 78-80
-
-
Barhanin, J.1
-
2
-
-
0029854263
-
V LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel
-
Sanguinetti, M.C. et al. Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel. Nature 384, 80-83 (1996).
-
(1996)
Nature
, vol.384
, pp. 80-83
-
-
Sanguinetti, M.C.1
-
3
-
-
0030723260
-
Ks function
-
Splawski, I., Tristani-Firouzi, M., Lehmann, M.H., Sanguinetti, M.C. & Keating, M.T. Mutations in the hminK gene cause long QT syndrome and suppress IKs function. Nat. Genet. 17, 338-340 (1997).
-
(1997)
Nat. Genet.
, vol.17
, pp. 338-340
-
-
Splawski, I.1
Tristani-Firouzi, M.2
Lehmann, M.H.3
Sanguinetti, M.C.4
Keating, M.T.5
-
4
-
-
9844261701
-
IsK and KvLQT1: Mutation in either of the two subunits of the slow component of the delayed rectifer potassium channel can cause Jervell and Lange-Nielsen syndrome
-
Tyson, J. et al. IsK and KvLQT1: mutation in either of the two subunits of the slow component of the delayed rectifer potassium channel can cause Jervell and Lange-Nielsen syndrome. Hum. Mol. Genet. 6, 2179-2185 (1997).
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 2179-2185
-
-
Tyson, J.1
-
5
-
-
0030872366
-
Kr
-
McDonald, T.V. et al. A minK-HERG complex regulates the cardiac potassium current IKr. Nature 388, 289-292 (1997).
-
(1997)
Nature
, vol.388
, pp. 289-292
-
-
McDonald, T.V.1
-
6
-
-
0033574273
-
Kr potassium channels with HERG and is associated with cardiac arrhythmia
-
Abbott, G.W. et al. MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia. Cell 97, 175-187 (1999).
-
(1999)
Cell
, vol.97
, pp. 175-187
-
-
Abbott, G.W.1
-
8
-
-
0028914969
-
A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
-
Curran, M.E. et al. A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome. Cell 80, 795-803 (1995).
-
(1995)
Cell
, vol.80
, pp. 795-803
-
-
Curran, M.E.1
-
9
-
-
0037428218
-
KCNQ1 gain-of-function mutation in familial atrial fbrillation
-
Chen, Y.H. et al. KCNQ1 gain-of-function mutation in familial atrial fbrillation. Science 299, 251-254 (2003).
-
(2003)
Science
, vol.299
, pp. 251-254
-
-
Chen, Y.H.1
-
10
-
-
22544466166
-
Atrial fbrillation-associated minK38G/S polymorphism modulates delayed rectifer current and membrane localization
-
Ehrlich, J.R., Zicha, S., Coutu, P. , Hebert, T.E. & Nattel, S. Atrial fbrillation-associated minK38G/S polymorphism modulates delayed rectifer current and membrane localization. Cardiovasc. Res. 67, 520-528 (2005).
-
(2005)
Cardiovasc. Res.
, vol.67
, pp. 520-528
-
-
Ehrlich, J.R.1
Zicha, S.2
Coutu, P.3
Hebert, T.E.4
Nattel, S.5
-
11
-
-
22144496096
-
Atrial fbrillation in KCNE1-null mice
-
Temple, J. et al. Atrial fbrillation in KCNE1-null mice. Circ. Res. 97, 62-69 (2005).
-
(2005)
Circ. Res.
, vol.97
, pp. 62-69
-
-
Temple, J.1
-
12
-
-
6344292572
-
Identifcation of a KCNE2 gain-of-function mutation in patients with familial atrial fbrillation
-
Yang, Y. et al. Identifcation of a KCNE2 gain-of-function mutation in patients with familial atrial fbrillation. Am. J. Hum. Genet. 75, 899-905 (2004).
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 899-905
-
-
Yang, Y.1
-
13
-
-
0034642569
-
A constitutively open potassium channel formed by KCNQ1 and KCNE3
-
Schroeder, B.C. et al. A constitutively open potassium channel formed by KCNQ1 and KCNE3. Nature 403, 196-199 (2000).
-
(2000)
Nature
, vol.403
, pp. 196-199
-
-
Schroeder, B.C.1
-
14
-
-
0034518479
-
Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice
-
Lee, M.P. et al. Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice. J. Clin. Invest. 106, 1447-1455 (2000).
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1447-1455
-
-
Lee, M.P.1
-
15
-
-
33747723381
-
The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion
-
Roepke, T.K. et al. The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion. J. Biol. Chem. 281, 23740-23747 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 23740-23747
-
-
Roepke, T.K.1
-
16
-
-
0030053759
-
Cloning and characterization of the thyroid iodide transporter
-
Dai, G., Levy, O. & Carrasco, N. Cloning and characterization of the thyroid iodide transporter. Nature 379, 458-460 (1996).
-
(1996)
Nature
, vol.379
, pp. 458-460
-
-
Dai, G.1
Levy, O.2
Carrasco, N.3
-
17
-
-
0037326161
-
The sodium/iodide symporter (NIS): Characterization, regulation and medical signifcance
-
Dohán, O. et al. The sodium/iodide symporter (NIS): characterization, regulation and medical signifcance. Endocr. Rev. 24, 48-77 (2003).
-
(2003)
Endocr. Rev.
, vol.24
, pp. 48-77
-
-
Dohán, O.1
-
18
-
-
0003425462
-
A common polymorphism associated with antibiotic-induced cardiac arrhythmia
-
Sesti, F. et al. A common polymorphism associated with antibiotic-induced cardiac arrhythmia. Proc. Natl. Acad. Sci. USA 97, 10613-10618 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10613-10618
-
-
Sesti, F.1
-
19
-
-
54049142897
-
to,f
-
Roepke, T.K. et al. Targeted deletion of Kcne2 impairs ventricular repolarization via disruption of IK,slow1 and Ito,f. FASEB J. 22, 3648-3660 (2008).
-
(2008)
FASEB J.
, vol.22
, pp. 3648-3660
-
-
Roepke, T.K.1
-
20
-
-
47949122658
-
The Frank-Starling mechanism in vertebrate cardiac myocytes
-
Shiels, H.A. & White, E. The Frank-Starling mechanism in vertebrate cardiac myocytes. J. Exp. Med. 211, 2005-2013 (2008).
-
(2008)
J. Exp. Med.
, vol.211
, pp. 2005-2013
-
-
Shiels, H.A.1
White, E.2
-
21
-
-
0019163924
-
Sequential changes in the pituitary-thyroid axis during pregnancy and lactation in the rat
-
Fukuda, H., Ohshima, K., Mori, M., Kobayashi, I. & Greer, M.A. Sequential changes in the pituitary-thyroid axis during pregnancy and lactation in the rat. Endocrinology 107, 1711-1716 (1980).
-
(1980)
Endocrinology
, vol.107
, pp. 1711-1716
-
-
Fukuda, H.1
Ohshima, K.2
Mori, M.3
Kobayashi, I.4
Greer, M.A.5
-
22
-
-
0035105852
-
Pregnancy and murine thyroiditis: Thyroglobulin immunization leads to fetal loss in specifc allogeneic pregnancies
-
Imaizumi, M. et al. Pregnancy and murine thyroiditis: thyroglobulin immunization leads to fetal loss in specifc allogeneic pregnancies. Endocrinology 142, 823-829 (2001).
-
(2001)
Endocrinology
, vol.142
, pp. 823-829
-
-
Imaizumi, M.1
-
23
-
-
33745567574
-
Dermatologic aspects of thyroid disease
-
Burman, K.D. & McKinley-Grant, L. Dermatologic aspects of thyroid disease. Clin. Dermatol. 24, 247-255 (2006).
-
(2006)
Clin. Dermatol.
, vol.24
, pp. 247-255
-
-
Burman, K.D.1
McKinley-Grant, L.2
-
24
-
-
30944459664
-
Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood fow, loss of arterioles and severe systolic dysfunction
-
Tang, Y.D. et al. Low thyroid function leads to cardiac atrophy with chamber dilatation, impaired myocardial blood fow, loss of arterioles and severe systolic dysfunction. Circulation 112, 3122-3130 (2005).
-
(2005)
Circulation
, vol.112
, pp. 3122-3130
-
-
Tang, Y.D.1
-
25
-
-
0034802582
-
Colocalization of KCNQ1/KCNE channel subunits in the mouse gastrointestinal tract
-
Dedek, K. & Waldegger, S. Colocalization of KCNQ1/KCNE channel subunits in the mouse gastrointestinal tract. Pfugers Arch. 442, 896-902 (2001).
-
(2001)
Pfugers Arch.
, vol.442
, pp. 896-902
-
-
Dedek, K.1
Waldegger, S.2
-
26
-
-
0035051670
-
+ channel KCNQ1 is essential for gastric acid secretion
-
Grahammer, F. et al. The cardiac K+ channel KCNQ1 is essential for gastric acid secretion. Gastroenterology 120, 1363-1371 (2001).
-
(2001)
Gastroenterology
, vol.120
, pp. 1363-1371
-
-
Grahammer, F.1
-
27
-
-
0141502227
-
Effect of hypothyroidism on hormone profles in virgin, pregnant and lactating rats and on lactation
-
Hapon, M.B., Simoncini, M., Via, G. & Jahn, G.A. Effect of hypothyroidism on hormone profles in virgin, pregnant and lactating rats and on lactation. Reproduction 126, 371-382 (2003).
-
(2003)
Reproduction
, vol.126
, pp. 371-382
-
-
Hapon, M.B.1
Simoncini, M.2
Via, G.3
Jahn, G.A.4
-
28
-
-
0013987360
-
Dependence of renal clearance of radioiodide on sex, age and thyroidal status
-
Oddie, T.H., Meade, J.H. Jr., Myhill, J. & Fisher, D.A. Dependence of renal clearance of radioiodide on sex, age and thyroidal status. J. Clin. Endocrinol. Metab. 26, 1293-1296 (1966).
-
(1966)
J. Clin. Endocrinol. Metab.
, vol.26
, pp. 1293-1296
-
-
Oddie, T.H.1
Meade Jr., J.H.2
Myhill, J.3
Fisher, D.A.4
-
29
-
-
0030890712
-
KvLQT1, a voltage-gated potassium channel responsible for human cardiac arrhythmias
-
Yang, W.P. et al. KvLQT1, a voltage-gated potassium channel responsible for human cardiac arrhythmias. Proc. Natl. Acad. Sci. USA 94, 4017-4021 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4017-4021
-
-
Yang, W.P.1
-
30
-
-
0035956935
-
Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange-Nielsen syndrome
-
Casimiro, M.C. et al. Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange-Nielsen syndrome. Proc. Natl. Acad. Sci. USA 98, 2526-2531 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 2526-2531
-
-
Casimiro, M.C.1
-
31
-
-
9444276084
-
Heightened susceptibility to chronic gastritis, hyperplasia and metaplasia in Kcnq1 mutant mice
-
Elso, C.M. et al. Heightened susceptibility to chronic gastritis, hyperplasia and metaplasia in Kcnq1 mutant mice. Hum. Mol. Genet. 13, 2813-2821 (2004).
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2813-2821
-
-
Elso, C.M.1
-
32
-
-
0036274768
-
The quantity of thyroid hormone in human milk is too low to infuence plasma thyroid hormone levels in the very preterm infant
-
van Wassenaer, A.G. et al. The quantity of thyroid hormone in human milk is too low to infuence plasma thyroid hormone levels in the very preterm infant. Clin. Endocrinol. 56, 621-627 (2002).
-
(2002)
Clin. Endocrinol.
, vol.56
, pp. 621-627
-
-
Van Wassenaer, A.G.1
-
33
-
-
10344230404
-
Molecular genetic defects in congenital hypothyroidism
-
Grüters, A., Krude, H. & Biebermann, H. Molecular genetic defects in congenital hypothyroidism. Eur. J. Endocrinol. 151 Suppl 3, U39-U44 (2004).
-
(2004)
Eur. J. Endocrinol.
, vol.151
, Issue.SUPPL 3
-
-
Grüters, A.1
Krude, H.2
Biebermann, H.3
-
34
-
-
0033835541
-
The mammary gland iodide transporter is expressed during lactation and in breast cancer
-
Tazebay, U.H. et al. The mammary gland iodide transporter is expressed during lactation and in breast cancer. Nat. Med. 6, 871-878 (2000).
-
(2000)
Nat. Med.
, vol.6
, pp. 871-878
-
-
Tazebay, U.H.1
-
35
-
-
34548709204
-
Contribution of KCNQ1 to the regulatory volume decrease in the human mammary epithelial cell line, MCF-7
-
VanTol, B.L. et al. Contribution of KCNQ1 to the regulatory volume decrease in the human mammary epithelial cell line, MCF-7. Am. J. Physiol. Cell Physiol. 293, C1010-C1019 (2007).
-
(2007)
Am. J. Physiol. Cell Physiol.
, vol.293
-
-
Vantol, B.L.1
-
37
-
-
33745208288
-
Gestational hypothyroxinemia and cognitive function in offspring
-
Kasatkina, E.P. et al. Gestational hypothyroxinemia and cognitive function in offspring. Neurosci. Behav. Physiol. 36, 619-624 (2006).
-
(2006)
Neurosci. Behav. Physiol.
, vol.36
, pp. 619-624
-
-
Kasatkina, E.P.1
-
38
-
-
33846506140
-
Immunological abortion: The thyroid factor
-
Palagiano, A. Immunological abortion: the thyroid factor. Minerva Ginecol. 58, 471-477 (2006).
-
(2006)
Minerva Ginecol.
, vol.58
, pp. 471-477
-
-
Palagiano, A.1
-
39
-
-
33745814396
-
Consequences of combined maternal, fetal and persistent postnatal hypothyroidism on the development of auditory function in Tshrhyt mutant mice
-
Song, L, McGee, J.A. & Walsh, E.J. Consequences of combined maternal, fetal and persistent postnatal hypothyroidism on the development of auditory function in Tshrhyt mutant mice. Brain Res. 1101, 59-72 (2006).
-
(2006)
Brain Res.
, vol.1101
, pp. 59-72
-
-
Song, L.1
McGee, J.A.2
Walsh, E.J.3
-
40
-
-
53249115469
-
Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring
-
Opazo, M.C. et al. Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring. Endocrinology 149, 5097-5106 (2008).
-
(2008)
Endocrinology
, vol.149
, pp. 5097-5106
-
-
Opazo, M.C.1
-
41
-
-
0026052186
-
Increased mean serum thyrotropin in apparently euthyroid hypercholesterolemic patients: Does it mean occult hypothyroidism?
-
Pallas, D. et al. Increased mean serum thyrotropin in apparently euthyroid hypercholesterolemic patients: does it mean occult hypothyroidism? J. Endocrinol. Invest. 14, 743-746 (1991).
-
(1991)
J. Endocrinol. Invest.
, vol.14
, pp. 743-746
-
-
Pallas, D.1
-
42
-
-
0025140879
-
Subclinical hypothyroidism: A review of neuropsychiatric aspects
-
Haggerty, J.J. Jr. et al. Subclinical hypothyroidism: a review of neuropsychiatric aspects. Int. J. Psychiatry Med. 20, 193-208 (1990).
-
(1990)
Int. J. Psychiatry Med.
, vol.20
, pp. 193-208
-
-
Haggerty Jr., J.J.1
-
43
-
-
0025786875
-
The common fnding of covert hypothyroidism at initial clinical evaluation for hyperlipoproteinemia
-
Glueck, C.J., Lang, J., Tracy, T. & Speirs, J. The common fnding of covert hypothyroidism at initial clinical evaluation for hyperlipoproteinemia. Clin. Chim. Acta 201, 113-122 (1991).
-
(1991)
Clin. Chim. Acta
, vol.201
, pp. 113-122
-
-
Glueck, C.J.1
Lang, J.2
Tracy, T.3
Speirs, J.4
-
44
-
-
70749096913
-
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
-
Kathiresan, S. et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat. Genet. 41, 334-341 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 334-341
-
-
Kathiresan, S.1
-
45
-
-
0034651789
-
Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: The Rotterdam study
-
Hak, A.E. et al. Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: the Rotterdam study. Ann. Intern. Med. 132, 270-278 (2000).
-
(2000)
Ann. Intern. Med.
, vol.132
, pp. 270-278
-
-
Hak, A.E.1
-
46
-
-
49449106134
-
Subclinical hypothyroidism is characterized by increased QT interval dispersion among women
-
Bakiner, O. et al. Subclinical hypothyroidism is characterized by increased QT interval dispersion among women. Med. Princ. Pract. 17, 390-394 (2008).
-
(2008)
Med. Princ. Pract.
, vol.17
, pp. 390-394
-
-
Bakiner, O.1
-
47
-
-
0027997922
-
Low serum thyrotropin concentrations as a risk factor for atrial fbrillation in older persons
-
Sawin, C.T. et al. Low serum thyrotropin concentrations as a risk factor for atrial fbrillation in older persons. N. Engl. J. Med. 331, 1249-1252 (1994).
-
(1994)
N. Engl. J. Med.
, vol.331
, pp. 1249-1252
-
-
Sawin, C.T.1
-
48
-
-
0031854859
-
Epidemiology and classifcation of atrial fbrillation
-
Lévy, S. Epidemiology and classifcation of atrial fbrillation. J. Cardiovasc. Electrophysiol. 9, S78-S82 (1998).
-
(1998)
J. Cardiovasc. Electrophysiol.
, vol.9
-
-
Lévy, S.1
-
49
-
-
0018760983
-
Occult thyrotoxicosis: A correctable cause of 'idiopathic' atrial fbrillation
-
Forfar, J.C., Miller, H.C. & Toft, A.D. Occult thyrotoxicosis: a correctable cause of 'idiopathic' atrial fbrillation. Am. J. Cardiol. 44, 9-12 (1979).
-
(1979)
Am. J. Cardiol.
, vol.44
, pp. 9-12
-
-
Forfar, J.C.1
Miller, H.C.2
Toft, A.D.3
-
50
-
-
0019975769
-
Management of atrial fbrillation in the post-thyrotoxic state
-
Nakazawa, H.K., Sakurai, K., Hamada, N., Momotani, N. & Ito, K. Management of atrial fbrillation in the post-thyrotoxic state. Am. J. Med. 72, 903-906 (1982).
-
(1982)
Am. J. Med.
, vol.72
, pp. 903-906
-
-
Nakazawa, H.K.1
Sakurai, K.2
Hamada, N.3
Momotani, N.4
Ito, K.5
-
51
-
-
33750348298
-
Postmortem long QT syndrome genetic testing for sudden unexplained death in the young
-
Tester, D.J. & Ackerman, MJ. Postmortem long QT syndrome genetic testing for sudden unexplained death in the young. J. Am. Coll. Cardiol. 49, 240-246 (2007).
-
(2007)
J. Am. Coll. Cardiol.
, vol.49
, pp. 240-246
-
-
Tester, D.J.1
Ackerman, M.J.2
-
52
-
-
12544257550
-
Sodium channel mutations and susceptibility to heart failure and atrial fbrillation
-
Olson, T.M. et al. Sodium channel mutations and susceptibility to heart failure and atrial fbrillation. J. Am. Med. Assoc. 293, 447-454 (2005).
-
(2005)
J. Am. Med. Assoc.
, vol.293
, pp. 447-454
-
-
Olson, T.M.1
-
53
-
-
10644247765
-
Heteromeric KCNE2/KCNQ1 potassium channels in the luminal membrane of gastric parietal cells
-
Heitzmann, D. et al. Heteromeric KCNE2/KCNQ1 potassium channels in the luminal membrane of gastric parietal cells. J. Physiol. (Lond.) 561, 547-557 (2004).
-
(2004)
J. Physiol. (Lond.)
, vol.561
, pp. 547-557
-
-
Heitzmann, D.1
-
54
-
-
0037235626
-
Fast colorimetric method for measuring urinary iodine
-
Gnat, D. et al. Fast colorimetric method for measuring urinary iodine. Clin. Chem. 49, 186-188 (2003).
-
(2003)
Clin. Chem.
, vol.49
, pp. 186-188
-
-
Gnat, D.1
-
55
-
-
0034646890
-
3,5,3′-triiodothyronine administered to rat dams during lactation increases milk yield and triglyceride concentration and hastens pups growth
-
Quevedo-Corona, L. et al. 3,5,3′-triiodothyronine administered to rat dams during lactation increases milk yield and triglyceride concentration and hastens pups growth. Life Sci. 66, 2013-2021 (2000)
-
(2000)
Life Sci.
, vol.66
, pp. 2013-2021
-
-
Quevedo-Corona, L.1
|