Age-related endothelial dysfunction in human skeletal muscle feed arteries: the role of free radicals derived from mitochondria in the vasculature

Acta Physiologica

Volumn 222, Issue 1, 2018, Pages

  Park, S Y ^a   Kwon, O S ^b,c   Andtbacka, R H I ^c   Hyngstrom, J R ^c   Reese, V ^b   Murphy, M P ^d   Richardson, R S ^b,c,e  

^a UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e UNIVERSITY OF UTAH   (United States)

Author keywords

ageing; endothelial dependent vasodilation; mitochondria targeted antioxidant; MitoQ; nitric oxide bioavailability

Indexed keywords

10-(6'-UBIQUINONYL)DECYLTRIPHENYLPHOSPHONIUM BROMIDE; ANTIOXIDANT; FREE RADICAL; ORGANOPHOSPHORUS COMPOUND; UBIQUINONE; ACETYLCHOLINE; BETA ACTIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MANGANESE SUPEROXIDE DISMUTASE; N(G) METHYLARGININE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM; SUPEROXIDE;

ADULT; AGED; AGING; ANALOGS AND DERIVATIVES; ARTERY; DRUG EFFECT; FEMALE; HUMAN; MALE; METABOLISM; MITOCHONDRION; PATHOLOGY; SKELETAL MUSCLE; VASCULAR ENDOTHELIUM; VASCULARIZATION; VASODILATATION; AGE; ARTICLE; BIOAVAILABILITY; CLINICAL ARTICLE; ENDOTHELIAL DYSFUNCTION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN TISSUE; MUSCLE BLOOD VESSEL; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RESPIRATORY CHAIN; SHEAR STRESS;

ADULT; AGED; AGING; ANTIOXIDANTS; ARTERIES; ENDOTHELIUM, VASCULAR; FEMALE; FREE RADICALS; HUMANS; MALE; MITOCHONDRIA; MUSCLE, SKELETAL; ORGANOPHOSPHORUS COMPOUNDS; UBIQUINONE; VASODILATION;

EID: 85020259680     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12893     Document Type: Article

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