A severe asthma disease signature from gene expression profiling of peripheral blood from U-BIOPRED cohorts

American Journal of Respiratory and Critical Care Medicine

Volumn 195, Issue 10, 2017, Pages 1311-1320

  Bigler, Jeannette ^a,l   Boedigheimer, Michael ^b   Schofield, James P R ^c   Skipp, Paul J ^c   Corfield, Julie ^d,e   Rowe, Anthony ^f   Sousa, Ana R ^g   Timour, Martin ^a   Twehues, Lori ^b   Hu, Xuguang ^b   Roberts, Graham ^h   Welcher, Andrew A ^b   Yu, Wen ^a,m   Lefaudeux, Diane ⁱ   De Meulder, Bertrand ⁱ   Auffray, Charles ⁱ   Chung, Kian F ^j   Adcock, Ian M ^j   Sterk, Peter J ^k   Djukanović, Ratko ^h  

^a AMGEN INC   (United States)

^b AMGEN INC   (United States)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d ASTRAZENECA R AND D   (Sweden)

^e Areteva R and D   (United Kingdom)

^f JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^g GLAXOSMITHKLINE   (United Kingdom)

^h UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

ⁱ CNRS   (France)

^j ROYAL BROMPTON AND HAREFIELD NHS FOUNDATION TRUST   (United Kingdom)

^k UNIVERSITY OF AMSTERDAM   (Netherlands)

^l BJ Group LLC   (United States)

^m MEDIMMUNE   (United States)

more..

Author keywords

Biomarker; Immune cell; Microarray

Indexed keywords

ANXA3 PROTEIN; BPI PROTEIN; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 6; CCL23 PROTEIN; CD24 ANTIGEN; CEACAM8 PROTEIN; CEBPE PROTEIN; CRISP3 PROTEIN; CTSG PROTEIN; CYCLIC AMP; DEFA1 PROTEIN; DEFA4 PROTEIN; F5 PROTEIN; FKBP5 PROTEIN; GAPT PROTEIN; HP PROTEIN; LTF PROTEIN; MS4A3 PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; NEUTROPHIL COLLAGENASE; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; NITRIC OXIDE; OLFM4 PROTEIN; PNPLA1 PROTEIN; PROTEIN; RNASE2 PROTEIN; RNASE3 PROTEIN; SLPI PROTEIN; STXBP5 PROTEIN; TCN1 PROTEIN; UNCLASSIFIED DRUG; CORTICOSTEROID; TRANSCRIPTOME;

ADULT; ARTICLE; ASTHMA; B LYMPHOCYTE; BLOOD ANALYSIS; BONE MARROW CELL; CELL MIGRATION; CELL POPULATION; CHEMOTAXIS; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; EOSINOPHIL; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; IMMUNOCOMPETENT CELL; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; MONOCYTE; MULTICENTER STUDY; NEUTROPHIL COUNT; PRIORITY JOURNAL; PROSPECTIVE STUDY; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; BLOOD; CLINICAL TRIAL; CLUSTER ANALYSIS; DRUG EFFECTS; EUROPE; MIDDLE AGED; PROCEDURES; SEVERITY OF ILLNESS INDEX; STATISTICS AND NUMERICAL DATA;

ADRENAL CORTEX HORMONES; ADULT; ASTHMA; CLUSTER ANALYSIS; COHORT STUDIES; EUROPE; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MALE; MICROARRAY ANALYSIS; MIDDLE AGED; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TRANSCRIPTOME;

EID: 85019892751     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201604-0866OC     Document Type: Article

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