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Volumn 15, Issue 6, 2017, Pages 3575-3582

Role of the Wnt/β-catenin signaling pathway in inducing apoptosis and Renal fibrosis in 5/6-nephrectomized rats

Author keywords

Apoptosis; Chronic kidney disease; Fibrosis; Renal; Wnt catenin signaling

Indexed keywords

BETA CATENIN; CASPASE 3; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; FIBRONECTIN; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; WNT PROTEIN; BIOLOGICAL MARKER;

EID: 85019629599     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2017.6461     Document Type: Article
Times cited : (42)

References (31)
  • 1
    • 84896736285 scopus 로고    scopus 로고
    • Risk factors for chronic kidney disease: An update
    • Kazancioǧlu R: Risk factors for chronic kidney disease: An update. Kidney Int Suppl (2011) 3:368-371, 2013.
    • (2011) Kidney Int Suppl , vol.3 , pp. 368-371
    • Kazancioǧlu, R.1
  • 3
    • 84868650760 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: A promising new target for fibrosis diseases
    • Guo Y, Xiao L, Sun L and Liu F: Wnt/beta-catenin signaling: A promising new target for fibrosis diseases. Physiol Res 61:337-346, 2012.
    • (2012) Physiol Res , vol.61 , pp. 337-346
    • Guo, Y.1    Xiao, L.2    Sun, L.3    Liu, F.4
  • 5
    • 33847350691 scopus 로고    scopus 로고
    • Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
    • Wynn TA: Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J Clin Invest 117:524-529, 2007.
    • (2007) J Clin Invest , vol.117 , pp. 524-529
    • Wynn, T.A.1
  • 6
    • 79551521517 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition (EMT) in kidney fibrosis: Fact or fantasy?
    • Kriz W, Kaissling B and Le Hir M: Epithelial-mesenchymal transition (EMT) in kidney fibrosis: Fact or fantasy? J Clin Invest 121:468-474, 2011.
    • (2011) J Clin Invest , vol.121 , pp. 468-474
    • Kriz, W.1    Kaissling, B.2    Le Hir, M.3
  • 7
    • 2342643464 scopus 로고    scopus 로고
    • Beta-catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition
    • Eger A, Stockinger A, Park J, Langkopf E, Mikula M, Gotzmann J, Mikulits W, Beug H and Foisner R: Beta-catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition. Oncogene 23:2672-2680, 2004.
    • (2004) Oncogene , vol.23 , pp. 2672-2680
    • Eger, A.1    Stockinger, A.2    Park, J.3    Langkopf, E.4    Mikula, M.5    Gotzmann, J.6    Mikulits, W.7    Beug, H.8    Foisner, R.9
  • 8
    • 33746513742 scopus 로고    scopus 로고
    • Upregulation of the Wnt/beta-catenin pathway induced by transforming growth factor-beta in hypertrophic scars and keloids
    • Sato M: Upregulation of the Wnt/beta-catenin pathway induced by transforming growth factor-beta in hypertrophic scars and keloids. Acta Derm Venereol 86:300-307, 2006.
    • (2006) Acta Derm Venereol , vol.86 , pp. 300-307
    • Sato, M.1
  • 12
    • 65249134946 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling promotes renal interstitial fibrosis
    • He W, Dai C, Li Y, Zeng G, Monga S P and Liu Y: Wnt/beta-catenin signaling promotes renal interstitial fibrosis. J Am Soc Nephrol 20:765-776, 2009.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 765-776
    • He, W.1    Dai, C.2    Li, Y.3    Zeng, G.4    Monga, S.P.5    Liu, Y.6
  • 13
    • 80052335469 scopus 로고    scopus 로고
    • Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis
    • Hao S, He W, Li Y, Ding H, Hou Y, Nie J, Hou FF, Kahn M and Liu Y: Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis. J Am Soc Nephrol 22:1642-1653, 2011.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 1642-1653
    • Hao, S.1    He, W.2    Li, Y.3    Ding, H.4    Hou, Y.5    Nie, J.6    Hou, F.F.7    Kahn, M.8    Liu, Y.9
  • 16
    • 84905252842 scopus 로고    scopus 로고
    • Inhibition of Wnt/β-catenin signaling promotes epithelial differentiation of mesenchymal stem cells and repairs bleomycin-induced lung injury
    • Wang C, Zhu H, Sun Z, Xiang Z, Ge Y, Ni C, Luo Z, Qian W and Han X: Inhibition of Wnt/β-catenin signaling promotes epithelial differentiation of mesenchymal stem cells and repairs bleomycin-induced lung injury. Am J Physiol Cell Physiol 307:C234-C244, 2014.
    • (2014) Am J Physiol Cell Physiol , vol.307 , pp. C234-C244
    • Wang, C.1    Zhu, H.2    Sun, Z.3    Xiang, Z.4    Ge, Y.5    Ni, C.6    Luo, Z.7    Qian, W.8    Han, X.9
  • 18
    • 84924650343 scopus 로고    scopus 로고
    • Tanshinone IIA attenuates renal fibrosis and inflammation via altering expression of TGF-β/Smad and N F-κB signaling pathway in 5/6 nephrectomized rats
    • Wang DT, Huang RH, Cheng X, Zhang ZH, Yang YJ and Lin X: Tanshinone IIA attenuates renal fibrosis and inflammation via altering expression of TGF-β/Smad and N F-κB signaling pathway in 5/6 nephrectomized rats. Int Immunopharmacol 26:4-12, 2015.
    • (2015) Int Immunopharmacol , vol.26 , pp. 4-12
    • Wang, D.T.1    Huang, R.H.2    Cheng, X.3    Zhang, Z.H.4    Yang, Y.J.5    Lin, X.6
  • 19
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2-(Delta Delta C (T)) method
    • Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2-(Delta Delta C (T)) method. Methods 25:402-408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 20
    • 0037388638 scopus 로고    scopus 로고
    • Small interfering RNAs directed against β-catenin inhibit the in vitro and in vivo growth of colon cancer cells
    • Verma UN, Surabhi RM, Schmaltieg A, Becerra C and Gaynor RB: Small interfering RNAs directed against β-catenin inhibit the in vitro and in vivo growth of colon cancer cells. Clin Cancer Res 9:1291-1300, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 1291-1300
    • Verma, U.N.1    Surabhi, R.M.2    Schmaltieg, A.3    Becerra, C.4    Gaynor, R.B.5
  • 22
    • 84908499000 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling and kidney fibrosis
    • Tan RJ, Zhou D, Zhou L and Liu Y: Wnt/β-catenin signaling and kidney fibrosis. Kidney Int Suppl (2011) 4:84-90, 2014.
    • (2011) Kidney Int Suppl , vol.4 , pp. 84-90
    • Tan, R.J.1    Zhou, D.2    Zhou, L.3    Liu, Y.4
  • 23
    • 84955615234 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling in kidney injury and repair: A double-edged sword
    • Zhou D, Tan RJ, Fu H and Liu Y: Wnt/β-catenin signaling in kidney injury and repair: A double-edged sword. Lab Invest 96:156-167, 2016.
    • (2016) Lab Invest , vol.96 , pp. 156-167
    • Zhou, D.1    Tan, R.J.2    Fu, H.3    Liu, Y.4
  • 24
    • 84865262751 scopus 로고    scopus 로고
    • Role changes of β-catenin in kidney injury and repair
    • Peng J and Dong Z: Role changes of β-catenin in kidney injury and repair. Kidney Int 82:509-511, 2012.
    • (2012) Kidney Int , vol.82 , pp. 509-511
    • Peng, J.1    Dong, Z.2
  • 27
    • 85020438785 scopus 로고    scopus 로고
    • Sustained activation of Wnt/β-Catenin signaling drives AKI to CKD progression
    • Xiao L, Zhou D, Tan RJ, Fu H, Zhou L, Hou FF and Liu Y: Sustained activation of Wnt/β-Catenin signaling drives AKI to CKD progression. J Am Soc Nephrol 27:1724-1740, 2016.
    • (2016) J Am Soc Nephrol , vol.27 , pp. 1724-1740
    • Xiao, L.1    Zhou, D.2    Tan, R.J.3    Fu, H.4    Zhou, L.5    Hou, F.F.6    Liu, Y.7
  • 28
    • 38349045501 scopus 로고    scopus 로고
    • Simvastatin reverses high glucose-induced apoptosis of mesangial cells via modulation of Wnt Signaling pathway
    • Lin CL, Cheng H, Tung CW, Huang WJ, Chang PJ, Yang JT and Wang J Y: Simvastatin reverses high glucose-induced apoptosis of mesangial cells via modulation of Wnt Signaling pathway. Am J Nephrol 28:290-297, 2008.
    • (2008) Am J Nephrol , vol.28 , pp. 290-297
    • Lin, C.L.1    Cheng, H.2    Tung, C.W.3    Huang, W.J.4    Chang, P.J.5    Yang, J.T.6    Wang, J.Y.7
  • 30
    • 33846193290 scopus 로고    scopus 로고
    • The many ways of Wnt in cancer
    • Polakis P: The many ways of Wnt in cancer. CurrOpin Genet Dev 17:45-51, 2007.
    • (2007) CurrOpin Genet Dev , vol.17 , pp. 45-51
    • Polakis, P.1
  • 31
    • 84877090354 scopus 로고    scopus 로고
    • Loss of Klotho contributes to kidney injury by derepression of Wnt/β-Catenin signaling
    • Zhou L, Li Y, Zhou D, Tan RJ and Liu Y: Loss of Klotho contributes to kidney injury by derepression of Wnt/β-Catenin signaling. J Am Soc Nephrol 24:771-785, 2013.
    • (2013) J Am Soc Nephrol , vol.24 , pp. 771-785
    • Zhou, L.1    Li, Y.2    Zhou, D.3    Tan, R.J.4    Liu, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.