Inhibition of Wnt/β-catenin signaling promotes epithelial differentiation of mesenchymal stem cells and repairs bleomycin-induced lung injury

American Journal of Physiology - Cell Physiology

Volumn 307, Issue 3, 2014, Pages

  Wang, Cong ^a   Zhu, Huiming ^a   Sun, Zhaorui ^a   Xiang, Zou ^b   Ge, Yuanyuan ^a   Ni, Can ^a   Luo, Zhaowen ^a   Qian, Weiping ^c   Han, Xiaodong ^a  

^a NANJING UNIVERSITY   (China)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c SOUTHEAST UNIVERSITY   (China)

Author keywords

Alveolar type II epithelial cells; Bone marrow derived mesenchymal stem cells; Coculture; Idiopathic pulmonary fibrosis; Wnt catenin signaling pathway; XAV939

Indexed keywords

BETA CATENIN; SMALL MOLECULE TRANSPORT AGENT; UNCLASSIFIED DRUG; WNT PROTEIN; XAV 939;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEOMYCIN-INDUCED PULMONARY FIBROSIS; BONE MARROW CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL REGENERATION; COCULTURE; CONTROLLED STUDY; ENZYME INHIBITION; EPITHELIUM CELL; FIBROBLAST; IN VITRO STUDY; MALE; MESENCHYMAL STEM CELL; MOUSE; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; SURVIVAL RATE;

ALVEOLAR TYPE II EPITHELIAL CELLS; BONE MARROW-DERIVED MESENCHYMAL STEM CELLS; COCULTURE; IDIOPATHIC PULMONARY FIBROSIS; WNT/Β-CATENIN SIGNALING PATHWAY; XAV939;

3T3 CELLS; ANIMALS; APOPTOSIS; BETA CATENIN; BLEOMYCIN; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; COCULTURE TECHNIQUES; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; HETEROCYCLIC COMPOUNDS, 3-RING; IDIOPATHIC PULMONARY FIBROSIS; LUNG INJURY; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; MYOFIBROBLASTS; PULMONARY ALVEOLI; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84905252842     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00366.2013     Document Type: Article

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