Essential Elements of Multimodal Analgesia in Enhanced Recovery After Surgery (ERAS) Guidelines

Anesthesiology Clinics

Volumn 35, Issue 2, 2017, Pages e115-e143

  Beverly, Anair ^a   Kaye, Alan D ^b   Ljungqvist, Olle ^c   Urman, Richard D ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ÖREBRO UNIVERSITY   (Sweden)

Author keywords

Enhanced recovery; ERAS; Guidelines; Multimodal analgesia; Opiate sparing analgesia; Pain management; Pharmacology; Regional anesthesia

Indexed keywords

ACETYLSALICYLIC ACID; ALFENTANIL; ALVIMOPAN; ANALGESIC AGENT; ANTICONVULSIVE AGENT; BUPIVACAINE; CALCIUM CHANNEL BLOCKING AGENT; CELECOXIB; CODEINE; CYCLOOXYGENASE 2 INHIBITOR; DEXAMETHASONE; DIAMORPHINE; DICLOFENAC; FENTANYL; GABAPENTIN; IBUPROFEN; KETAMINE; KETOROLAC; LIDOCAINE; LOCAL ANESTHETIC AGENT; MORPHINE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; OXYCODONE; PARACETAMOL; PARECOXIB; PREGABALIN; REMIFENTANIL; TRAMADOL; UNINDEXED DRUG;

ANALGESIA; CONFUSION; CONSTIPATION; CONTINUOUS INFUSION; CONVALESCENCE; DIZZINESS; DROWSINESS; DRUG MECHANISM; DRUG POTENTIATION; ENHANCED RECOVERY AFTER SURGERY; EVIDENCE BASED PRACTICE; FATIGUE; HALLUCINATION; HOSPITAL ADMISSION; HUMAN; HYPOTENSION; ILEUS; MEDICAL SOCIETY; MORBIDITY; MULTIMODAL ANALGESIA; NAUSEA; NONHUMAN; PERIOPERATIVE PERIOD; POSTOPERATIVE PAIN; PRACTICE GUIDELINE; PRURITUS; RESPIRATION DEPRESSION; REVIEW; URINE RETENTION; ANESTHETIC RECOVERY; GENERAL ANESTHESIA; PAIN, POSTOPERATIVE; PHYSIOLOGICAL STRESS; PREOPERATIVE CARE; PROCEDURES; REGIONAL ANESTHESIA; STANDARDS;

ANALGESIA; ANESTHESIA RECOVERY PERIOD; ANESTHESIA, CONDUCTION; ANESTHESIA, GENERAL; HUMANS; PAIN MANAGEMENT; PAIN, POSTOPERATIVE; PRACTICE GUIDELINES AS TOPIC; PREOPERATIVE CARE; SOCIETIES, MEDICAL; STRESS, PHYSIOLOGICAL;

EID: 85019571824     PISSN: 19322275     EISSN: 22103538     Source Type: Journal    
DOI: 10.1016/j.anclin.2017.01.018     Document Type: Review

References (181)

1. Fearon, K.C., Ljungqvist, O., Von Meyenfeldt, M., et al. Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 24:3 (2005), 466–477.
2. Lassen, K., Soop, M., Nygren, J., et al. Consensus review of optimal perioperative care in colorectal surgery: Enhanced Recovery After Surgery (ERAS) Group recommendations. Arch Surg 144:10 (2009), 961–969.
3. Gustafsson, U.O., Scott, M.J., Schwenk, W., et al. Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations. World J Surg 37:2 (2013), 259–284.
4. Cerantola, Y., Valerio, M., Persson, B., et al. Guidelines for perioperative care after radical cystectomy for bladder cancer: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations. Clin Nutr 32:6 (2013), 879–887.
5. Lassen, K., Coolsen, M.M., Slim, K., et al. Guidelines for perioperative care for pancreaticoduodenectomy: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations. World J Surg 37:2 (2013), 240–258.
6. Nygren, J., Thacker, J., Carli, F., et al. Guidelines for perioperative care in elective rectal or pelvic surgery: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations. World J Surg 37:2 (2013), 285–305.
7. Mortensen, K., Nilsson, M., Slim, K., et al. Consensus guidelines for enhanced recovery after gastrectomy: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations. Br J Surg 101:10 (2014), 1209–1229.
8. Nelson, G., Altman, A.D., Nick, A., et al. Guidelines for postoperative care in gynecologic/oncology surgery: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations–Part II. Gynecol Oncol 140:2 (2016), 323–332.
9. Nelson, G., Altman, A.D., Nick, A., et al. Guidelines for pre- and intra-operative care in gynecologic/oncology surgery: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations–Part I. Gynecol Oncol 140:2 (2016), 313–322.
10. Thorell, A., MacCormick, A.D., Awad, S., et al. Guidelines for perioperative care in bariatric surgery: Enhanced Recovery After Surgery (ERAS) Society recommendations. World J Surg 40 (2016), 2065–2083.
11. Guyatt, G.H., Oxman, A.D., Vist, G.E., et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 336:7650 (2008), 924–926.
12. Lynch, M., Pain as the fifth vital sign. J Intraven Nurs 24:2 (2001), 85–94.
13. Moraca, R.J., Sheldon, D.G., Thirlby, R.C., The role of epidural anesthesia and analgesia in surgical practice. Ann Surg 238:5 (2003), 663–673.
14. Breivik, H., Stubhaug, A., Management of acute postoperative pain: still a long way to go!. Pain 137:2 (2008), 233–234.
15. Chang, S.H., Maney, K.M., Mehta, V., et al. Pain assessment and management in medical wards: an area of unmet need. Postgrad Med J 86:1015 (2010), 279–284.
16. Gordon, D.B., Pellino, T.A., Miaskowski, C., et al. A 10-year review of quality improvement monitoring in pain management: recommendations for standardized outcome measures. Pain Manag Nurs 3:4 (2002), 116–130.
17. Oderda, G.M., Evans, R.S., Lloyd, J., et al. Cost of opioid-related adverse drug events in surgical patients. J Pain Symptom Manage 25:3 (2003), 276–283.
18. Koppert, W., Schmelz, M., The impact of opioid-induced hyperalgesia for postoperative pain. Best Pract Res Clin Anaesthesiol 21:1 (2007), 65–83.
19. Joshi, G.P., Kehlet, H., Rawal, N., Evidence-based guidelines for postoperative pain management. Reg Anesth Pain Med, 32(2), 2007, 173.
20. Neugebauer, E.A., Wilkinson, R.C., Kehlet, H., et al. PROSPECT: a practical method for formulating evidence-based expert recommendations for the management of postoperative pain. Surg Endosc 21:7 (2007), 1047–1053.
21. Chou, R., Gordon, D.B., de Leon-Casasola, O.A., et al. Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists’ Committee on Regional Anesthesia, Executive Committee, and Administrative Council. J Pain 17:2 (2016), 131–157.
22. Amini, N., Kim, Y., Hyder, O., et al. A nationwide analysis of the use and outcomes of perioperative epidural analgesia in patients undergoing hepatic and pancreatic surgery. Am J Surg 210:3 (2015), 483–491.
23. Gritsenko, K., Khelemsky, Y., Kaye, A.D., et al. Multimodal therapy in perioperative analgesia. Best Pract Res Clin Anaesthesiol 28:1 (2014), 59–79.
24. Prabhakar, A., Mancuso, K.F., Owen, C.P., et al. Perioperative analgesia outcomes and strategies. Best Pract Res Clin Anaesthesiol 28:2 (2014), 105–115.
25. Beverly, A., Kaye, A.D., Urman, R.D., SCAMPs for Multimodal Post-Operative Analgesia: A Concept to Standardize and Individualize Care. Curr Pain Headache Rep, 21(1), 2017, 5.
26. Prabhakar, A., Cefalu, J.N., Rowe, J.S., et al. Techniques to Optimize Multimodal Analgesia in Ambulatory Surgery. Curr Pain Headache Rep, 21(5), 2017, 24.
27. Feldheiser, A., Aziz, O., Baldini, G., et al. Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 2: consensus statement for anaesthesia practice. Acta Anaesthesiol Scand 60:3 (2016), 289–334.
28. Scott, M.J., Baldini, G., Fearon, K.C., et al. Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 1: pathophysiological considerations. Acta Anaesthesiol Scand 59:10 (2015), 1212–1231.
29. Wu, C.L., Rowlingson, A.J., Partin, A.W., et al. Correlation of postoperative pain to quality of recovery in the immediate postoperative period. Reg Anesth Pain Med 30:6 (2005), 516–522.
30. Marret, E., Kurdi, O., Zufferey, P., et al. Effects of nonsteroidal antiinflammatory drugs on patient-controlled analgesia morphine side effects: meta-analysis of randomized controlled trials. Anesthesiology 102:6 (2005), 1249–1260.
31. Mathiesen, O., Wetterslev, J., Kontinen, V.K., et al. Adverse effects of perioperative paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review. Acta Anaesthesiol Scand 58:10 (2014), 1182–1198.
32. Nussmeier, N.A., Whelton, A.A., Brown, M.T., et al. Safety and efficacy of the cyclooxygenase-2 inhibitors parecoxib and valdecoxib after noncardiac surgery. Anesthesiology 104:3 (2006), 518–526.
33. Remy, C., Marret, E., Bonnet, F., Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials. Br J Anaesth 94:4 (2005), 505–513.
34. Klein, M., Postoperative non-steroidal anti-inflammatory drugs and colorectal anastomotic leakage. NSAIDs and anastomotic leakage. Dan Med J, 59(3), 2012, B4420.
35. Burton, T.P., Mittal, A., Soop, M., Nonsteroidal anti-inflammatory drugs and anastomotic dehiscence in bowel surgery: systematic review and meta-analysis of randomized, controlled trials. Dis Colon Rectum 56:1 (2013), 126–134.
36. Gorissen, K.J., Benning, D., Berghmans, T., et al. Risk of anastomotic leakage with non-steroidal anti-inflammatory drugs in colorectal surgery. Br J Surg 99:5 (2012), 721–727.
37. Apfel, C.C., Turan, A., Souza, K., et al. Intravenous acetaminophen reduces postoperative nausea and vomiting: a systematic review and meta-analysis. Pain 154:5 (2013), 677–689.
38. Brick, N., Premedication for anxiety in adult day surgery patients. AORN J 92:1 (2010), 101–102.
39. Levy, B.F., Scott, M.J., Fawcett, W.J., et al. Optimizing patient outcomes in laparoscopic surgery. Colorectal Dis 13:Suppl 7 (2011), 8–11.
40. Jorgensen, H., Wetterslev, J., Moiniche, S., et al. Epidural local anaesthetics versus opioid-based analgesic regimens on postoperative gastrointestinal paralysis, PONV and pain after abdominal surgery. Cochrane Database Syst Rev(4), 2000 CD001893.
41. Marret, E., Remy, C., Bonnet, F., Postoperative Pain Forum Group. Meta-analysis of epidural analgesia versus parenteral opioid analgesia after colorectal surgery. Br J Surg 94:6 (2007), 665–673.
42. Marana, E., Colicci, S., Meo, F., et al. Neuroendocrine stress response in gynecological laparoscopy: TIVA with propofol versus sevoflurane anesthesia. J Clin Anesth 22:4 (2010), 250–255.
43. Liu, Y., Zheng, Y., Gu, X., et al. The efficacy of NMDA receptor antagonists for preventing remifentanil-induced increase in postoperative pain and analgesic requirement: a meta-analysis. Minerva Anestesiol 78:6 (2012), 653–667.
44. Marret, E., Rolin, M., Beaussier, M., et al. Meta-analysis of intravenous lidocaine and postoperative recovery after abdominal surgery. Br J Surg 95:11 (2008), 1331–1338.
45. Wongyingsinn, M., Baldini, G., Charlebois, P., et al. Intravenous lidocaine versus thoracic epidural analgesia: a randomized controlled trial in patients undergoing laparoscopic colorectal surgery using an enhanced recovery program. Reg Anesth Pain Med 36:3 (2011), 241–248.
46. Hausel, J., Nygren, J., Lagerkranser, M., et al. A carbohydrate-rich drink reduces preoperative discomfort in elective surgery patients. Anesth analgesia 93:5 (2001), 1344–1350.
47. Convertino, V.A., Cardiovascular consequences of bed rest: effect on maximal oxygen uptake. Med Sci Sports Exerc 29:2 (1997), 191–196.
48. Zhu, Z., Wang, C., Xu, C., et al. Influence of patient-controlled epidural analgesia versus patient-controlled intravenous analgesia on postoperative pain control and recovery after gastrectomy for gastric cancer: a prospective randomized trial. Gastric Cancer 16:2 (2013), 193–200.
49. Kim, T.H., Kang, H., Choi, Y.S., et al. Pre- and intraoperative lidocaine injection for preemptive analgesics in laparoscopic gastrectomy: a prospective, randomized, double-blind, placebo-controlled study. J Laparoendosc Adv Surg Tech A 23:8 (2013), 663–668.
50. Chaparro, L.E., Clarke, H., Valdes, P.A., et al. Adding pregabalin to a multimodal analgesic regimen does not reduce pain scores following cosmetic surgery: a randomized trial. J Anesth 26:6 (2012), 829–835.
51. Tufanogullari, B., White, P.F., Peixoto, M.P., et al. Dexmedetomidine infusion during laparoscopic bariatric surgery: the effect on recovery outcome variables. Anesth analgesia 106:6 (2008), 1741–1748.
52. Maund, E., McDaid, C., Rice, S., et al. Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs for the reduction in morphine-related side-effects after major surgery: a systematic review. Br J Anaesth 106:3 (2011), 292–297.
53. Ziemann-Gimmel, P., Hensel, P., Koppman, J., et al. Multimodal analgesia reduces narcotic requirements and antiemetic rescue medication in laparoscopic Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis 9:6 (2013), 975–980.
54. Graves, D.A., Batenhorst, R.L., Bennett, R.L., et al. Morphine requirements using patient-controlled analgesia: influence of diurnal variation and morbid obesity. Clin Pharm 2:1 (1983), 49–53.
55. Meoli, A.L., Rosen, C.L., Kristo, D., et al. Upper airway management of the adult patient with obstructive sleep apnea in the perioperative period–avoiding complications. Sleep 26:8 (2003), 1060–1065.
56. Frey, W.C., Pilcher, J., Obstructive sleep-related breathing disorders in patients evaluated for bariatric surgery. Obes Surg 13:5 (2003), 676–683.
57. Maffezzini, M., Campodonico, F., Capponi, G., et al. Fast-track surgery and technical nuances to reduce complications after radical cystectomy and intestinal urinary diversion with the modified Indiana pouch. Surg Oncol 21:3 (2012), 191–195.
58. Toren, P., Ladak, S., Ma, C., et al. Comparison of epidural and intravenous patient controlled analgesia in patients undergoing radical cystectomy. Can J Urol 16:4 (2009), 4716–4720.
59. Stewart, D.E., Wong, F., Cheung, A.M., et al. Information needs and decisional preferences among women with ovarian cancer. Gynecol Oncol 77:3 (2000), 357–361.
60. Ong, C.K., Seymour, R.A., Lirk, P., et al. Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain. Anesth Analg 110:4 (2010), 1170–1179.
61. Niruthisard, S., Werawataganon, T., Bunburaphong, P., et al. Improving the analgesic efficacy of intrathecal morphine with parecoxib after total abdominal hysterectomy. Anesth analgesia 105:3 (2007), 822–824.
62. Alayed, N., Alghanaim, N., Tan, X., et al. Preemptive use of gabapentin in abdominal hysterectomy: a systematic review and meta-analysis. Obstet Gynecol 123:6 (2014), 1221–1229.
63. Kalogera, E., Bakkum-Gamez, J.N., Jankowski, C.J., et al. Enhanced recovery in gynecologic surgery. Obstet Gynecol 122:2 Pt 1 (2013), 319–328.
64. De Oliveira, G.S. Jr., Ahmad, S., Fitzgerald, P.C., et al. Dose ranging study on the effect of preoperative dexamethasone on postoperative quality of recovery and opioid consumption after ambulatory gynaecological surgery. Br J Anaesth 107:3 (2011), 362–371.
65. Macrae, W.A., Chronic post-surgical pain: 10 years on. Br J Anaesth 101:1 (2008), 77–86.
66. Hakkarainen, T.W., Steele, S.R., Bastaworous, A., et al. Nonsteroidal anti-inflammatory drugs and the risk for anastomotic failure: a report from Washington State's Surgical Care and Outcomes Assessment Program (SCOAP). JAMA Surg 150:3 (2015), 223–228.
67. Paulasir, S., Kaoutzanis, C., Welch, K.B., et al. Nonsteroidal Anti-inflammatory Drugs: Do They Increase the Risk of Anastomotic Leaks Following Colorectal Operations?. Dis Colon Rectum 58:9 (2015), 870–877.
68. Jongen, A.C., Bosmans, J.W., Kartal, S., et al. Predictive Factors for Anastomotic Leakage After Colorectal Surgery: Study Protocol for a Prospective Observational Study (REVEAL Study). JMIR Res Protoc, 5(2), 2016, e90.
69. Graham, G.G., Davies, M.J., Day, R.O., et al. The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings. Inflammopharmacology 21:3 (2013), 201–232.
70. Williams, D.G., Patel, A., Howard, R.F., Pharmacogenetics of codeine metabolism in an urban population of children and its implications for analgesic reliability. Br J Anaesth 89:6 (2002), 839–845.
71. Poston, S., Broder, M.S., Gibbons, M.M., et al. Impact of alvimopan (entereg) on hospital costs after bowel resection: results from a large inpatient database. P T 36:4 (2011), 209–220.
72. Berger, N.G., Ridolfi, T.J., Ludwig, K.A., Delayed gastrointestinal recovery after abdominal operation - role of alvimopan. Clin Exp Gastroenterol 8 (2015), 231–235.
73. Bhatia, A., Ketamine as an adjunct to patient-controlled analgesia: why, for whom, and how much?. Can J Anaesth 63:3 (2016), 262–264.
74. Jalili, M., Bahreini, M., Doosti-Irani, A., et al. Ketamine-propofol combination (ketofol) vs propofol for procedural sedation and analgesia: systematic review and meta-analysis. Am J Emerg Med 34:3 (2016), 558–569.
75. Siddiqui, K.M., Khan, F.A., Effect of preinduction low-dose ketamine bolus on intra operative and immediate postoperative analgesia requirement in day care surgery: A randomized controlled trial. Saudi J Anaesth 9:4 (2015), 422–427.
76. Wang, L., Johnston, B., Kaushal, A., et al. Ketamine added to morphine or hydromorphone patient-controlled analgesia for acute postoperative pain in adults: a systematic review and meta-analysis of randomized trials. Can J Anaesth 63:3 (2016), 311–325.
77. Samimi, S., Taheri, A., Davari Tanha, F., Comparison between intraperitoneal and intravenous lidocaine for postoperative analgesia after elective abdominal hysterectomy, a Double-Blind Placebo Controlled Study. J Fam Reprod Health 9:4 (2015), 193–198.
78. McCarthy, G.C., Megalla, S.A., Habib, A.S., Impact of intravenous lidocaine infusion on postoperative analgesia and recovery from surgery a systematic review of randomized controlled trials. Drugs 70 (2010), 1149–1163.
79. Wu, C.L., Cohen, S.R., Richman, J.M., et al. Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids: a meta-analysis. Anesthesiology 103:5 (2005), 1079–1088 [quiz: 1109–10].
80. Carli, F., Halliday, D., Continuous epidural blockade arrests the postoperative decrease in muscle protein fractional synthetic rate in surgical patients. Anesthesiology 86:5 (1997), 1033–1040.
81. Popping, D.M., Elia, N., Van Aken, H.K., et al. Impact of epidural analgesia on mortality and morbidity after surgery: systematic review and meta-analysis of randomized controlled trials. Ann Surg 259:6 (2014), 1056–1067.
82. Khan, S.A., Khokhar, H.A., Nasr, A.R., et al. Effect of epidural analgesia on bowel function in laparoscopic colorectal surgery: a systematic review and meta-analysis. Surg Endosc 27:7 (2013), 2581–2591.
83. Levy, B.F., Scott, M.J., Fawcett, W., et al. Randomized clinical trial of epidural, spinal or patient-controlled analgesia for patients undergoing laparoscopic colorectal surgery. Br J Surg 98:8 (2011), 1068–1078.
84. Manion, S.C., Brennan, T.J., Thoracic epidural analgesia and acute pain management. Anesthesiology 115:1 (2011), 181–188.
85. Rawal, N., Allvin, R., Epidural and intrathecal opioids for postoperative pain management in Europe–a 17-nation questionnaire study of selected hospitals. Euro Pain Study Group on Acute Pain. Acta Anaesthesiol Scand 40:9 (1996), 1119–1126.
86. Block, B.M., Liu, S.S., Rowlingson, A.J., et al. Efficacy of postoperative epidural analgesia: a meta-analysis. JAMA 290:18 (2003), 2455–2463.
87. Finucane, B.T., Ganapathy, S., Carli, F., et al. Prolonged epidural infusions of ropivacaine (2 mg/mL) after colonic surgery: the impact of adding fentanyl. Anesth analgesia 92:5 (2001), 1276–1285.
88. Niemi, G., Breivik, H., Epinephrine markedly improves thoracic epidural analgesia produced by a small-dose infusion of ropivacaine, fentanyl, and epinephrine after major thoracic or abdominal surgery: a randomized, double-blinded crossover study with and without epinephrine. Anesth analgesia 94:6 (2002), 1598–1605 [table of contents].
89. Niemi, G., Breivik, H., The minimally effective concentration of adrenaline in a low-concentration thoracic epidural analgesic infusion of bupivacaine, fentanyl and adrenaline after major surgery. A randomized, double-blind, dose-finding study. Acta Anaesthesiol Scand 47:4 (2003), 439–450.
90. Wongyingsinn, M., Baldini, G., Stein, B., et al. Spinal analgesia for laparoscopic colonic resection using an enhanced recovery after surgery programme: better analgesia, but no benefits on postoperative recovery: a randomized controlled trial. Br J Anaesth 108:5 (2012), 850–856.
91. Krishnamoorthy, K., Ravi, S., Ganesan, I., Evaluation of efficacy of epidural clonidine with 0.5% Bupivacaine for postoperative analgesia for orthopaedic lower limb surgeries. J Clin Diagn Res 9:9 (2015), UC14–UC18.
92. Feldheiser, A., Conroy, P., Bonomo, T., et al. Development and feasibility study of an algorithm for intraoperative goaldirected haemodynamic management in noncardiac surgery. J Int Med Res 40:4 (2012), 1227–1241.
93. Kim, J.Y., Lee, S.J., Koo, B.N., et al. The effect of epidural sufentanil in ropivacaine on urinary retention in patients undergoing gastrectomy. Br J Anaesth 97:3 (2006), 414–418.
94. Bertoglio, S., Fabiani, F., Negri, P.D., et al. The postoperative analgesic efficacy of preperitoneal continuous wound infusion compared to epidural continuous infusion with local anesthetics after colorectal cancer surgery: a randomized controlled multicenter study. Anesth analgesia 115:6 (2012), 1442–1450.
95. Jouve, P., Bazin, J.E., Petit, A., et al. Epidural versus continuous preperitoneal analgesia during fast-track open colorectal surgery: a randomized controlled trial. Anesthesiology 118:3 (2013), 622–630.
96. Boulind, C.E., Ewings, P., Bulley, S.H., et al. Feasibility study of analgesia via epidural versus continuous wound infusion after laparoscopic colorectal resection. Br J Surg 100:3 (2013), 395–402.
97. Niraj, G., Kelkar, A., Jeyapalan, I., et al. Comparison of analgesic efficacy of subcostal transversus abdominis plane blocks with epidural analgesia following upper abdominal surgery. Anaesthesia 66:6 (2011), 465–471.
98. Charlton, S., Cyna, A.M., Middleton, P., et al. Perioperative transversus abdominis plane (TAP) blocks for analgesia after abdominal surgery. Cochrane Database Syst Rev(12), 2010 CD007705.
99. Siddiqui, M.R., Sajid, M.S., Uncles, D.R., et al. A meta-analysis on the clinical effectiveness of transversus abdominis plane block. J Clin Anesth 23:1 (2011), 7–14.
100. Kahokehr, A., Sammour, T., Zargar Shoshtari, K., et al. Intraperitoneal local anesthetic improves recovery after colon resection: a double-blinded randomized controlled trial. Ann Surg 254:1 (2011), 28–38.
101. Kahokehr, A., Sammour, T., Srinivasa, S., et al. Systematic review and meta-analysis of intraperitoneal local anaesthetic for pain reduction after laparoscopic gastric procedures. Br J Surg 98:1 (2011), 29–36.
102. Buchanan, G.N., Malik, A., Parvaiz, A., et al. Laparoscopic resection for colorectal cancer. Br J Surg 95:7 (2008), 893–902.
103. Charghi, R., Backman, S., Christou, N., et al. Patient controlled i.v. analgesia is an acceptable pain management strategy in morbidly obese patients undergoing gastric bypass surgery. A retrospective comparison with epidural analgesia. Can J Anaesth 50:7 (2003), 672–678.
104. Wassef, M., Lee, D.Y., Levine, J.L., et al. Feasibility and analgesic efficacy of the transversus abdominis plane block after single-port laparoscopy in patients having bariatric surgery. J Pain Res 6 (2013), 837–841.
105. Kahokehr, A., Sammour, T., Soop, M., et al. Intraperitoneal use of local anesthetic in laparoscopic cholecystectomy: systematic review and metaanalysis of randomized controlled trials. J Hepatobiliary Pancreat Sci 17:5 (2010), 637–656.
106. Alkhamesi, N.A., Kane, J.M., Guske, P.J., et al. Intraperitoneal aerosolization of bupivacaine is a safe and effective method in controlling postoperative pain in laparoscopic Roux-en-Y gastric bypass. J Pain Res 1 (2008), 9–13.
107. Tangsiriwatthana, T., Sangkomkamhang, U.S., Lumbiganon, P., et al. Paracervical local anaesthesia for cervical dilatation and uterine intervention. Cochrane Database Syst Rev(1), 2009 CD005056.
108. Penketh, R., Griffiths, A., Chawathe, S., A prospective observational study of the safety and acceptability of vaginal hysterectomy performed in a 24-hour day case surgery setting. BJOG 114:4 (2007), 430–436.
109. Sprung, J., Sanders, M.S., Warner, M.E., et al. Pain relief and functional status after vaginal hysterectomy: intrathecal versus general anesthesia. Can J Anaesth 53:7 (2006), 690–700.
110. Chen, L.M., Weinberg, V.K., Chen, C., et al. Perioperative outcomes comparing patient controlled epidural versus intravenous analgesia in gynecologic oncology surgery. Gynecol Oncol 115:3 (2009), 357–361.
111. Belavy, D., Janda, M., Baker, J., et al. Epidural analgesia is associated with an increased incidence of postoperative complications in patients requiring an abdominal hysterectomy for early stage endometrial cancer. Gynecol Oncol 131:2 (2013), 423–429.
112. Massicotte, L., Chalaoui, K.D., Beaulieu, D., et al. Comparison of spinal anesthesia with general anesthesia on morphine requirement after abdominal hysterectomy. Acta Anaesthesiol Scand 53:5 (2009), 641–647.
113. Catro-Alves, L.J., De Azevedo, V.L., De Freitas Braga, T.F., et al. The effect of neuraxial versus general anesthesia techniques on postoperative quality of recovery and analgesia after abdominal hysterectomy: a prospective, randomized, controlled trial. Anesth analgesia 113:6 (2011), 1480–1486.
114. Borendal Wodlin, N., Nilsson, L., Kjolhede, P., et al. The impact of mode of anaesthesia on postoperative recovery from fast-track abdominal hysterectomy: a randomised clinical trial. BJOG 118:3 (2011), 299–308.
115. Karaman, S., Kocabas, S., Uyar, M., et al. Intrathecal morphine: effects on perioperative hemodynamics, postoperative analgesia, and stress response for total abdominal hysterectomy. Adv Ther 23:2 (2006), 295–306.
116. Carney, J., McDonnell, J.G., Ochana, A., et al. The transversus abdominis plane block provides effective postoperative analgesia in patients undergoing total abdominal hysterectomy. Anesth analgesia 107:6 (2008), 2056–2060.
117. Champaneria, R., Shah, L., Geoghegan, J., et al. Analgesic effectiveness of transversus abdominis plane blocks after hysterectomy: a meta-analysis. Eur J Obstet Gynecol Reprod Biol 166:1 (2013), 1–9.
118. Kristensen, B.B., Christensen, D.S., Ostergaard, M., et al. Lack of postoperative pain relief after hysterectomy using preperitoneally administered bupivacaine. Reg Anesth Pain Med 24:6 (1999), 576–580.
119. Leong, W.M., Lo, W.K., Chiu, J.W., Analgesic efficacy of continuous delivery of bupivacaine by an elastomeric balloon infusor after abdominal hysterectomy: a prospective randomised controlled trial. Aust N Z J Obstet Gynaecol 42:5 (2002), 515–518.
120. Kushner, D.M., LaGalbo, R., Connor, J.P., et al. Use of a bupivacaine continuous wound infusion system in gynecologic oncology: a randomized trial. Obstet Gynecol 106:2 (2005), 227–233.
121. Gupta, A., Perniola, A., Axelsson, K., et al. Postoperative pain after abdominal hysterectomy: a double-blind comparison between placebo and local anesthetic infused intraperitoneally. Anesth analgesia 99:4 (2004), 1173–1179 [table of contents].
122. Ng, A., Swami, A., Smith, G., et al. The analgesic effects of intraperitoneal and incisional bupivacaine with epinephrine after total abdominal hysterectomy. Anesth analgesia 95:1 (2002), 158–162 [table of contents].
123. Perniola, A., Gupta, A., Crafoord, K., et al. Intraabdominal local anaesthetics for postoperative pain relief following abdominal hysterectomy: a randomized, double-blind, dose-finding study. Eur J Anaesthesiol 26:5 (2009), 421–429.
124. Owusu-Agyemang, P., Soliz, J., Hayes-Jordan, A., et al. Safety of epidural analgesia in the perioperative care of patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. Ann Surg Oncol 21:5 (2014), 1487–1493.
125. Schmidt, C., Steinke, T., Moritz, S., et al. Thoracic epidural anesthesia in patients with cytoreductive surgery and HIPEC. J Surg Oncol 102:5 (2010), 545–546.
126. De Oliveira, G.S. Jr., Castro-Alves, L.J., Nader, A., et al. Transversus abdominis plane block to ameliorate postoperative pain outcomes after laparoscopic surgery: a meta-analysis of randomized controlled trials. Anesth analgesia 118:2 (2014), 454–463.
127. Arden, D., Seifert, E., Donnellan, N., et al. Intraperitoneal instillation of bupivacaine for reduction of postoperative pain after laparoscopic hysterectomy: a double-blind randomized controlled trial. J Minim Invasive Gynecol 20:5 (2013), 620–626.
128. Kaufman, Y., Hirsch, I., Ostrovsky, L., et al. Pain relief by continuous intraperitoneal nebulization of ropivacaine during gynecologic laparoscopic surgery–a randomized study and review of the literature. J Minim Invasive Gynecol 15:5 (2008), 554–558.
129. Shaw, I.C., Stevens, J., Krishnamurthy, S., The influence of intraperitoneal bupivacaine on pain following major laparoscopic gynaecological procedures. Anaesthesia 56:11 (2001), 1041–1044.
130. Segal, D., Awad, N., Nasir, H., et al. Combined spinal and general anesthesia vs general anesthesia for robotic sacrocervicopexy: a randomized controlled trial. Int Urogynecol J 25:3 (2014), 369–374.
131. Aboulian, A., Hassan, Z., Lin, M.Y., et al. Successful enhanced recovery program after colorectal surgery in a county institution. Am Surg 76:10 (2010), 1158–1162.
132. Varadhan, K.K., Neal, K.R., Dejong, C.H., et al. The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials. Clin Nutr 29:4 (2010), 434–440.
133. Wennstrom, B., Stomberg, M.W., Modin, M., et al. Patient symptoms after colonic surgery in the era of enhanced recovery–a long-term follow-up. J Clin Nurs 19:5–6 (2010), 666–672.
134. Aarts, M.A., Okrainec, A., Glicksman, A., et al. Adoption of enhanced recovery after surgery (ERAS) strategies for colorectal surgery at academic teaching hospitals and impact on total length of hospital stay. Surg Endosc 26:2 (2012), 442–450.
135. Yamada, T., Hayashi, T., Cho, H., et al. Usefulness of enhanced recovery after surgery protocol as compared with conventional perioperative care in gastric surgery. Gastric Cancer 15:1 (2012), 34–41.
136. Coolsen, M.M., Wong-Lun-Hing, E.M., van Dam, R.M., et al. A systematic review of outcomes in patients undergoing liver surgery in an enhanced recovery after surgery pathways. HPB (Oxford) 15:4 (2013), 245–251.
137. Bagnall, N.M., Malietzis, G., Kennedy, R.H., et al. A systematic review of enhanced recovery care after colorectal surgery in elderly patients. Colorectal Dis 16:12 (2014), 947–956.
138. Forsmo, H.M., Pfeffer, F., Rasdal, A., et al. Compliance with enhanced recovery after surgery criteria and preoperative and postoperative counselling reduces length of hospital stay in colorectal surgery: results of a randomized controlled trial. Colorectal Dis 18:6 (2016), 603–611.
139. Mannaerts, G.H., van Mil, S.R., Stepaniak, P.S., et al. Results of implementing an Enhanced Recovery After Bariatric Surgery (ERABS) Protocol. Obes Surg 26:2 (2016), 303–312.
140. Saver, C., Early results suggest merits of enhanced recovery after surgery. OR Manager 32(1):1 (2016), 8–10.
141. Stone, A.B., Grant, M.C., Pio Roda, C., et al. Implementation costs of an enhanced recovery after surgery program in the united states: a financial model and sensitivity analysis based on experiences at a Quaternary Academic Medical Center. J Am Coll Surg 222:3 (2016), 219–225.
142. Xiong, J., Szatmary, P., Huang, W., et al. Enhanced Recovery After Surgery Program in Patients Undergoing Pancreaticoduodenectomy: A PRISMA-Compliant Systematic Review and Meta-Analysis. Medicine (Baltimore), 95(18), 2016, e3497.
143. ERAS Compliance Group. The impact of enhanced recovery protocol compliance on elective colorectal cancer resection: results from an international registry. Ann Surg 261:6 (2015), 1153–1159.
144. Nelson, G., Kiyang, L.N., Crumley, E.T., et al. Implementation of Enhanced Recovery After Surgery (ERAS) Across a Provincial Healthcare System: The ERAS Alberta Colorectal Surgery Experience. World J Surg 40:5 (2016), 1092–1103.
145. Fleming, I.O., Garratt, C., Guha, R., et al. Aggregation of marginal gains in cardiac surgery: feasibility of a perioperative care bundle for enhanced recovery in cardiac surgical patients. J Cardiothorac Vasc Anesth 30:3 (2016), 665–670.
146. Auyong, D.B., Allen, C.J., Pahang, J.A., et al. Reduced Length of Hospitalization in Primary Total Knee Arthroplasty Patients Using an Updated Enhanced Recovery After Orthopedic Surgery (ERAS) Pathway. J Arthroplasty 30:10 (2015), 1705–1709.
147. Dias, A.S., Rinaldi, T., Barbosa, L.G., The impact of patients controlled analgesia undergoing orthopedic surgery. Braz J Anesthesiol 66:3 (2016), 265–271.
148. Tetsunaga, T., Sato, T., Shiota, N., et al. Comparison of continuous epidural analgesia, patient-controlled analgesia with morphine, and continuous three-in-one femoral nerve block on postoperative outcomes after total hip arthroplasty. Clin Orthop Surg 7:2 (2015), 164–170.
149. White, J.J., Houghton-Clemmey, R., Marval, P., Enhanced recovery after surgery (ERAS): an orthopaedic perspective. J Perioper Pract 23:10 (2013), 228–232.
150. Wright, J., Cullinger, B., Bacarese-Hamilton, I., Postoperative analgesia for Enhanced recovery in Joint replacement: Audit of a new electronic prescribing order set. BMJ Qual Improv Rep 4:1 (2015), 1–3.
151. Dizdarevic, A., Fernandes, A., Thoracic paravertebral block, multimodal analgesia, and monitored anesthesia care for breast cancer surgery in primary lateral sclerosis. Case Rep Anesthesiol, 2016, 2016, 6301358.
152. Zhang, X., Shu, L., Lin, C., et al. Comparison between intraoperative two-space injection thoracic paravertebral block and wound infiltration as a component of multimodal analgesia for postoperative pain management after video-assisted thoracoscopic lobectomy: a randomized controlled trial. J Cardiothorac Vasc Anesth 29:6 (2015), 1550–1556.
153. Bashandy, G.M., Abbas, D.N., Pectoral nerves I and II blocks in multimodal analgesia for breast cancer surgery: a randomized clinical trial. Reg Anesth Pain Med 40:1 (2015), 68–74.
154. Thomazeau, J., Rouquette, A., Martinez, V., et al. Acute pain Factors predictive of post-operative pain and opioid requirement in multimodal analgesia following knee replacement. Eur J Pain 20:5 (2016), 822–832.
155. Kim, S.I., Ha, K.Y., Oh, I.S., Preemptive multimodal analgesia for postoperative pain management after lumbar fusion surgery: a randomized controlled trial. Eur Spine J 25:5 (2016), 1614–1619.
156. Greze, J., Vighetti, A., Incagnoli, P., et al. Does continuous wound infiltration enhance baseline intravenous multimodal analgesia after posterior spinal fusion surgery? A randomized, double-blinded, placebo-controlled study. Eur Spine J 26:3 (2017), 832–839.
157. Fabi, D.W., Multimodal analgesia in the hip fracture patient. J Orthop Trauma 30:Suppl 1 (2016), S6–S11.
158. Milani, P., Castelli, P., Sola, M., et al. Multimodal analgesia in total knee arthroplasty: a randomized, double-blind, controlled trial on additional efficacy of periarticular anesthesia. J Arthroplasty 30:11 (2015), 2038–2042.
159. Halawi, M.J., Grant, S.A., Bolognesi, M.P., Multimodal analgesia for total joint arthroplasty. Orthopedics 38:7 (2015), e616–e625.
160. Cho, C.H., Song, K.S., Min, B.W., et al. Efficacy of interscalene block combined with multimodal pain control for postoperative analgesia after rotator cuff repair. Knee Surg Sports Traumatol Arthrosc 23:2 (2015), 542–547.
161. Pearse, R.M., Moreno, R.P., Bauer, P., et al. European Surgical Outcomes Study (EuSOS) group for the trials groups of the European Society of Intensive Care Medicine and the European Society of Anaesthesiology. Lancet 380:9847 (2012), 1059–1065.
162. Quiney, N., Aggarwal, G., Scott, M., et al. Survival after emergency general surgery: what can we learn from enhanced recovery programmes?. World J Surg 40:6 (2016), 1283–1287.
163. Lohsiriwat, V., Enhanced recovery after surgery vs conventional care in emergency colorectal surgery. World J Gastroenterol 20:38 (2014), 13950–13955.
164. Wisely, J.C., Barclay, K.L., Effects of an Enhanced Recovery After Surgery programme on emergency surgical patients. ANZ J Surg 86:11 (2016), 883–888.
165. Pearse, R.M., Harrison, D.A., James, P., et al. Identification and characterisation of the high-risk surgical population in the United Kingdom. Crit Care, 10(3), 2006, R81.
166. Pearse, R.M., Moreno, R.P., Bauer, P., et al. Mortality after surgery in Europe: a 7 day cohort study. Lancet 380:9847 (2012), 1059–1065.
167. Lee, M., Silverman, S.M., Hansen, H., et al. A comprehensive review of opioid-induced hyperalgesia. Pain Physician 14:2 (2011), 145–161.
168. Huxtable, C.A., Roberts, L.J., Somogyi, A.A., et al. Acute pain management in opioid-tolerant patients: a growing challenge. Anaesth Intensive Care 39:5 (2011), 804–823.
169. Lerchl-Wanie, G., Angster, R., Perioperative analgesia for opioid tolerant patients. Anaesthesist 59:7 (2010), 657–670 [quiz: 671–2]. [in German].
170. Cakmakkaya, O.S., Kolodzie, K., Apfel, C.C., et al. Anaesthetic techniques for risk of malignant tumour recurrence. Cochrane Database Syst Rev(11), 2014 CD008877.
171. Hooijmans, C.R., Geessink, F.J., Ritskes-Hoitinga, M., et al. A systematic review of the modifying effect of anaesthetic drugs on metastasis in animal models for cancer. PLoS One, 11(5), 2016, e0156152.
172. Sun, Y., Li, T., Gan, T.J., The effects of perioperative regional anesthesia and analgesia on cancer recurrence and survival after oncology surgery: a systematic review and meta-analysis. Reg Anesth Pain Med 40:5 (2015), 589–598.
173. Kaye, A.D., Patel, N., Bueno, F.R., et al. Effect of opiates, anesthetic techniques, and other perioperative factors on surgical cancer patients. Ochsner J 14:2 (2014), 216–228.
174. Forget, P., Vandenhende, J., Berliere, M., et al. Do intraoperative analgesics influence breast cancer recurrence after mastectomy? A retrospective analysis. Anesth analgesia 110:6 (2010), 1630–1635.
175. Gustafsson, U.O., Oppelstrup, H., Thorell, A., Nygren, J., et al. Adherence to the ERAS-protocol is associated with 5-year survival after colorectal cancer surgery: A retrospective cohort study. World J Surg 40:7 (2016), 1741–1747.
176. Akkaya, T., Ozkan, D., Chronic post-surgical pain. Agri 21:1 (2009), 1–9.
177. Humble, S.R., Dalton, A.J., Li, L., A systematic review of therapeutic interventions to reduce acute and chronic post-surgical pain after amputation, thoracotomy or mastectomy. Eur J Pain 19:4 (2015), 451–465.
178. Nelson, G., Kiyang, L.N., Crumley, E.T., et al. Implementation of Enhanced Recovery after Surgery (ERAS) Across a Provincial Healthcare System: The ERAS Alberta Colorectal Surgery Experience. World J Surg 40:5 (2016), 1092–1103.
179. Meadows, K.A., Patient-reported outcome measures: an overview. Br J Community Nurs 16:3 (2011), 146–151.
180. Black, N., Patient reported outcome measures could help transform healthcare. BMJ, 346, 2013, f167.
181. Black, N., Varaganum, M., Hutchings, A., Relationship between patient reported experience (PREMs) and patient reported outcomes (PROMs) in elective surgery. BMJ Qual Saf 23:7 (2014), 534–542.