Ketamine added to morphine or hydromorphone patient-controlled analgesia for acute postoperative pain in adults: a systematic review and meta-analysis of randomized trials;Addition de kétamine à la morphine ou l’hydromorphone dans l’analgésie contrôlée par le patient pour les douleurs postopératoires aiguës chez l’adulte: revue systématique et méta-analyse des essais randomisés

Canadian Journal of Anesthesia

Volumn 63, Issue 3, 2016, Pages 311-325

  Wang, Li ^a,b,c   Johnston, Bradley ^d,e   Kaushal, Alka ^d,f   Cheng, Davy ^a   Zhu, Fang ^a   Martin, Janet ^a,g  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c SICHUAN UNIVERSITY   (China)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f MCMASTER UNIVERSITY   (Canada)

^g WESTERN UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROMORPHONE; KETAMINE; MORPHINE; DRUG COMBINATION;

ARTICLE; CARDIOVASCULAR DISEASE; DIPLOPIA; DRUG EFFICACY; HUMAN; META ANALYSIS; MOBILIZATION; PAIN INTENSITY; PATIENT CONTROLLED ANALGESIA; PATIENT SATISFACTION; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESPIRATION DEPRESSION; RISK BENEFIT ANALYSIS; SYSTEMATIC REVIEW; TREATMENT DURATION; TREATMENT OUTCOME; URINE RETENTION; VISUAL ANALOG SCALE; ACUTE PAIN; ADULT; DRUG COMBINATION; OUTCOME ASSESSMENT; PAIN, POSTOPERATIVE; PROCEDURES; PUBLISHING;

ACUTE PAIN; ADULT; ANALGESIA, PATIENT-CONTROLLED; DRUG COMBINATIONS; HUMANS; HYDROMORPHONE; KETAMINE; MORPHINE; OUTCOME ASSESSMENT (HEALTH CARE); PAIN, POSTOPERATIVE; PATIENT SATISFACTION; PUBLICATION BIAS; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84957939696     PISSN: 0832610X     EISSN: 14968975     Source Type: Journal    
DOI: 10.1007/s12630-015-0551-4     Document Type: Article

References (53)

1. Niesters M, Martini C, Dahan A. Ketamine for chronic pain: risks and benefits. Br J Clin Pharmacol 2014; 77: 357-67.
2. Bell RF, Dahl JB, Moore RA, Kalso E. Perioperative ketamine for acute postoperative pain. Cochrane Database Syst Rev 2006; 1: CD004603.
3. Carstensen M, Moller AM. Adding ketamine to morphine for intravenous patient-controlled analgesia for acute postoperative pain: a qualitative review of randomized trials. Br J Anaesth 2010; 104: 401-6.
4. Elia N, Tramer MR. Ketamine and postoperative pain—a quantitative systematic review of randomised trials. Pain 2005; 113: 61-70.
5. Laskowski K, Stirling A, McKay WP, Lim HJ. A systematic review of intravenous ketamine for postoperative analgesia. Can J Anesth 2011; 58: 911-23.
6. Subramaniam K, Subramaniam B, Steinbrook RA. Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review. Anesth Analg 2004; 99: 482-95.
7. Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 2009; 62: 1006-12.
8. Schmid RL, Sandler AN, Katz J. Use and efficacy of low-dose ketamine in the management of acute postoperative pain: a review of current techniques and outcomes. Pain 1999; 82: 111-25.
9. Higgins JP, Green S. Cochrane Handbook for Systematic Reviews of Interventions. The Cochrane Collaboration, 2011. Available from URL: www.cochrane-handbook.org (accessed July 2015).
10. Thorlund K, Walter SD, Johnston BC, Furukawa TA, Guyatt GH. Pooling health-related quality of life outcomes in meta-analysis—a tutorial and review of methods for enhancing interpretability. Res Synth Methods 2011; 2: 188-203.
11. Guyatt GH, Oxman AD, Vist GE, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008; 336: 924-6.
12. Guyatt G, Oxman AD, Akl EA, et al. GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol 2011; 64: 383-94.
13. Guyatt GH, Oxman AD, Montori V, et al. GRADE guidelines: 5. Rating the quality of evidence—publication bias. J Clin Epidemiol 2011; 64: 1277-82.
14. Guyatt GH, Oxman AD, Kunz R, et al. GRADE guidelines: 7. Rating the quality of evidence—inconsistency. J Clin Epidemiol 2011; 64: 1294-302.
15. Guyatt GH, Oxman AD, Kunz R, et al. GRADE guidelines: 8. Rating the quality of evidence—indirectness. J Clin Epidemiol 2011; 64: 1303-10.
16. Guyatt GH, Oxman AD, Santesso N, et al. GRADE guidelines: 12. Preparing summary of findings tables-binary outcomes. J Clin Epidemiol 2013; 66: 158-72.
17. Guyatt GH, Thorlund K, Oxman AD, et al. GRADE guidelines: 13. Preparing summary of findings tables and evidence profiles-continuous outcomes. J Clin Epidemiol 2013; 66: 173-83.
18. Adriaenssens G, Vermeyen KM, Hoffmann VL, Mertens E, Adriaensen HF. Postoperative analgesia with i.v. patient-controlled morphine: effect of adding ketamine. Br J Anaesth 1999; 83: 393-6.
19. Atangana R, Ngowe Ngowe M, Binam F, Sosso MA. Morphine versus morphine-ketamine association in the management of post operative pain in thoracic surgery. Acta Anaesthesiol Belg 2007; 58: 125-7.
20. Aubrun F, Gaillat C, Rosenthal D, et al. Effect of a low-dose ketamine regimen on pain, mood, cognitive function and memory after major gynaecological surgery: a randomized, double-blind, placebo-controlled trial. Eur J Anaesthesiol 2008; 25: 97-105.
21. Bilgen S, Koner O, Ture H, Menda F, Ficicioglu C, Aykac B. Effect of three different doses of ketamine prior to general anaesthesia on postoperative pain following caesarean delivery: a prospective randomized study. Minerva Anestesiol 2012; 78: 442-9.
22. Burstal R, Danjoux G, Hayes C, Lantry G. PCA ketamine and morphine after abdominal hysterectomy. Anaesth Intensive Care 2001; 29: 246-51.
23. Chazan S, Buda I, Nesher N, Paz J, Weinbroum A. Low-dose ketamine via intravenous patient-controlled analgesia device after various transthoracic procedures improves analgesia and patient and family satisfaction. Pain Manag Nurs 2010; 11: 169-76.
24. Dahi-Taleghani M, Fazli B, Ghasemi M, Vosoughian M, Dabbagh A. Effect of intravenous patient controlled ketamine analgesiaon postoperative pain in opium abusers. Anesth Pain Med 2014; 4: e14129.
25. Grady MV, Mascha E, Sessler DI, Kurz A. The effect of perioperative intravenous lidocaine and ketamine on recovery after abdominal hysterectomy. Anesth Analg 2012; 115: 1078-84.
26. Guillou N, Tanguy M, Seguin P, Branger B, Campion JP, Malledant Y. The effects of small-dose ketamine on morphine consumption in surgical intensive care unit patients after major abdominal surgery. Anesth Analg 2003; 97: 843-7.
27. Hercock T, Gillham MJ, Sleigh J, Jones SF. The addition of ketamine to patient controlled morphine analgesia does not improve quality of analgesia after total abdominal hysterectomy. Acute Pain 1999; 2: 68-72.
28. Javery KB, Ussery TW, Steger HG, Colclough GW. Comparison of morphine and morphine with ketamine for postoperative analgesia. Can J Anaesth 1996; 43: 212-5.
29. Jensen LL, Handberg G, Helbo-Hansen HS, et al. No morphine sparing effect of ketamine added to morphine for patient-controlled intravenous analgesia after uterine artery embolization. Acta Anaesthesiol Scand 2008; 52: 479-86.
30. Kamal HM. Ketamine as an adjuvant to morphine for patient controlled analgesia in morbidly obese patients. J Med Sci 2008; 8: 364-70.
31. Kollender Y, Bickels J, Stocki D, et al. Subanaesthetic ketamine spares postoperative morphine and controls pain better than standard morphine does alone in orthopaedic-oncological patients. Eur J Cancer 2008; 44: 954-62.
32. Lo A, Macpherson N, Spiwak R. Prospective randomized trial of patient-controlled analgesia with ketamine and morphine or morphine alone after hysterectomy. Can J Hosp Pharm 2008; 61: 334-9.
33. Martinez V, Cymerman A, Ben Ammar S, et al. The analgesic efficiency of combined pregabalin and ketamine for total hip arthroplasty: a randomised, double-blind, controlled study. Anaesthesia 2014; 69: 46-52.
34. McKay WP, Donais P. Bowel function after bowel surgery: morphine with ketamine or placebo; a randomized controlled trial pilot study. Acta Anaesthesiol Scand 2007; 51: 1166-71.
35. Michelet P, Guervilly C, Helaine A, et al. Adding ketamine to morphine for patient-controlled analgesia after thoracic surgery: influence on morphine consumption, respiratory function, and nocturnal desaturation. Br J Anaesth 2007; 99: 396-403.
36. Murdoch CJ, Crooks BA, Miller CD. Effect of the addition of ketamine to morphine in patient-controlled analgesia. Anaesthesia 2002; 57: 484-8.
37. Nesher N, Ekstein MP, Paz Y, Marouani N, Chazan S, Weinbroum AA. Morphine with adjuvant ketamine vs higher dose of morphine alone for immediate postthoracotomy analgesia. Chest 2009; 136: 245-52.
38. Nesher N, Serovian I, Marouani N, Chazan S, Weinbroum AA. Ketamine spares morphine consumption after transthoracic lung and heart surgery without adverse hemodynamic effects. Pharmacol Res 2008; 58: 38-44.
39. Nitta R, Goyagi T, Nishikawa T. Combination of oral clonidine and intravenous low-dose ketamine reduces the consumption of postoperative patient-controlled analgesia morphine after spine surgery. Acta Anaesthesiol Taiwan 2013; 51: 14-7.
40. Reeves M, Lindholm DE, Myles PS, Fletcher H, Hunt JO. Adding ketamine to morphine for patient-controlled analgesia after major abdominal surgery: a double-blinded, randomized controlled trial. Anesth Analg 2001; 93: 116-20.
41. Sami Mebazaa M, Mestiri T, Kaabi B, Ben Ammar MS. Clinical benefits related to the combination of ketamine with morphine for patient controlled analgesia after major abdominal surgery. Tunis Med 2008; 86: 435-40.
42. Snijdelaar DG, Cornelisse HB, Schmid RL, Katz J. A randomised, controlled study of peri-operative low dose s(+)-ketamine in combination with postoperative patient-controlled s(+)-ketamine and morphine after radical prostatectomy. Anaesthesia 2004; 59: 222-8.
43. Sveticic G, Farzanegan F, Zmoos P, Zmoos S, Eichenberger U, Curatolo M. Is the combination of morphine with ketamine better than morphine alone for postoperative intravenous patient-controlled analgesia? Anesth Analg 2008; 106: 287-93.
44. Unlugenc H, Ozalevli M, Guler T, Isik G. Postoperative pain management with intravenous patient-controlled morphine: comparison of the effect of adding magnesium or ketamine. Eur J Anaesthesiol 2003; 20: 416-21.
45. Zakine J, Samarcq D, Lorne E, et al. Postoperative ketamine administration decreases morphine consumption in major abdominal surgery: a prospective, randomized, double-blind, controlled study. Anesth Analg 2008; 106: 1856-61.
46. Barreveld AM, Correll DJ, Liu X, et al. Ketamine decreases postoperative pain scores in patients taking opioids for chronic pain: results of a prospective, randomized, double-blind study. Pain Medicine 2013; 14: 925-34.
47. Subramaniam K, Akhouri V, Glazer PA, et al. Intra- and postoperative very low dose intravenous ketamine infusion does not increase pain relief after major spine surgery in patients with preoperative narcotic analgesic intake. Pain Med 2011; 12: 1276-83.
48. Urban MK, Ya Deau JT, Wukovits B, Lipnitsky JY. Ketamine as an adjunct to postoperative pain management in opioid tolerant patients after spinal fusions: a prospective randomized trial. HSS J 2008; 4: 62-5.
49. Dang XJ, Su SY, Sun LL, He LH, Wu JR. Analgesic effect of ketamine adding to morphine in patient-controlled analgesia for patients after surgery for femur fracture (Chinese). Guang Dong Yi Xue 2013; 34: 608-11.
50. Liu GK, Huang YG, Luo AL, Ren HZ, Zhang YF. Patient-controlled intravenous morphine and ketamine for postoperative analgesia (Chinese). Zhong Hua Ma Zui Xue Za Zhi 2003; 23: 416-8.
51. Wang Q, Wang ZC, Wang BG. Continuous intravenous infusion of low dose of ketamine combined with morphine used for postoperative analgesia in patients with cervical spinal cord injury (Chinese). Zhong Guo Kang Fu Li Lun Yu Shi Jian 2007; 13: 86-8.
52. Wu MY, Xing CY, Ren YC, Y. DL, Liu B, Jiang H. Effects of perioperative low dose ketamine (Chinese). Di Si Jun Yi Da Xue Xue Bao 2004; 25: 2161.
53. Wu YQ, Li H, Xiong JC, et al. Effects of patient-controlled analgesia with small dose ketamine combined with morphine and the influence thereof on plasma β-endorphin level in patients after radical operation for esophageal carcinoma. Zhonghua Yi Xue Za Zhi 2009; 89: 314-7.