Increased glucocorticoid receptor expression in sepsis is related to heat shock proteins, cytokines, and cortisol and is associated with increased mortality

Intensive Care Medicine Experimental

Volumn 5, Issue 1, 2017, Pages

  Vardas, Konstantinos ^a,b   Ilia, Stavroula ^b   Sertedaki, Amalia ^a   Charmandari, Evangelia ^a   Briassouli, Efrossini ^a   Goukos, Dimitris ^a   Apostolou, Kleovoulos ^a   Psarra, Katerina ^c   Botoula, Efthimia ^c   Tsagarakis, Stylianos ^c   Magira, Eleni ^a   Routsi, Christina ^a   Stratakis, Constantine A ^d   Nanas, Serafim ^a   Briassoulis, George ^b  

^a UNIVERSITY OF ATHENS   (Greece)

^b UNIVERSITY HOSPITAL OF IRAKLION   (Greece)

^c EVANGELISMOS HOSPITAL   (Greece)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Cortisol; Glucocorticoid receptor (GR); Heat shock protein 72; HSP90 ; Sepsis; SIRS

Indexed keywords

C REACTIVE PROTEIN; CD33 ANTIGEN; CD45 ANTIGEN; CYTOKINE; GAMMA INTERFERON; GLUCOCORTICOID RECEPTOR; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 72; HEAT SHOCK PROTEIN 90; HYDROCORTISONE; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; PROCALCITONIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HYDROCORTISONE BLOOD LEVEL; IMMUNOASSAY ANALYZER; KRUSKAL WALLIS TEST; LEUKOCYTE; MALE; MONOCYTE; MORTALITY; NEUTROPHIL; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; RECEIVER OPERATING CHARACTERISTIC; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPSIS; SEPTIC SHOCK; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; SIMPLIFIED ACUTE PHYSIOLOGY SCORE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 85019360682     PISSN: None     EISSN: 2197425X     Source Type: Journal    
DOI: 10.1186/s40635-017-0123-8     Document Type: Article

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