-
1
-
-
84931577486
-
Activity-induced DNA breaks govern the expression of neuronal early-response genes
-
Madabhushi, R., et al. Activity-induced dna breaks govern the expression of neuronal early-response genes. Cell 161, 1592-1605 (2015).
-
(2015)
Cell
, vol.161
, pp. 1592-1605
-
-
Madabhushi, R.1
-
2
-
-
84958205734
-
Transcription-Associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells
-
Schwer, B., et al. Transcription-Associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells. Proc. Natl Acad. Sci. USA 113, 2258-2263 (2016).
-
(2016)
Proc. Natl Acad. Sci. USA
, vol.113
, pp. 2258-2263
-
-
Schwer, B.1
-
3
-
-
84886035850
-
Meiotic recombination in mammals: Localization and regulation
-
Baudat, F., Imai, Y., & de Massy, B. Meiotic recombination in mammals: localization and regulation. Nat. Rev. Genet. 14, 794-806 (2013).
-
(2013)
Nat. Rev. Genet
, vol.14
, pp. 794-806
-
-
Baudat, F.1
Imai, Y.2
De Massy, B.3
-
4
-
-
80355122714
-
V(D) J Recombination mechanisms of initiation
-
Schatz, D. G., & Swanson, P. C. V(D)J Recombination: mechanisms of initiation. Annu. Rev. Genet. 45, 167-202 (2011).
-
(2011)
Annu. Rev. Genet
, vol.45
, pp. 167-202
-
-
Schatz, D.G.1
Swanson, P.C.2
-
5
-
-
77649175453
-
Genomic instability-An evolving hallmark of cancer
-
Negrini, S., Gorgoulis, V. G., & Halazonetis, T. D. Genomic instability-An evolving hallmark of cancer. Nat. Rev. Mol. Cell Biol. 11, 220-228 (2010).
-
(2010)
Nat. Rev. Mol. Cell Biol
, vol.11
, pp. 220-228
-
-
Negrini, S.1
Gorgoulis, V.G.2
Halazonetis, T.D.3
-
6
-
-
84902096048
-
Development and applications of CRISPR-Cas9 for genome engineering
-
Hsu, P. D., Lander, E. S., & Zhang, F. Development and applications of CRISPR-Cas9 for genome engineering. Cell 157, 1262-1278 (2014).
-
(2014)
Cell
, vol.157
, pp. 1262-1278
-
-
Hsu, P.D.1
Lander, E.S.2
Zhang, F.3
-
7
-
-
77949275845
-
Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX
-
Szilard, R. K., et al. Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX. Nat. Struct. Mol. Biol. 17, 299-305 (2010).
-
(2010)
Nat. Struct. Mol. Biol
, vol.17
, pp. 299-305
-
-
Szilard, R.K.1
-
8
-
-
77951498531
-
High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome
-
Iacovoni, J. S., et al. High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome. EMBO J. 29, 1446-1457 (2010).
-
(2010)
EMBO J
, vol.29
, pp. 1446-1457
-
-
Iacovoni, J.S.1
-
9
-
-
84875754465
-
Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing
-
Crosetto, N., et al. Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing. Nat. Methods 10, 361-365 (2013).
-
(2013)
Nat. Methods
, vol.10
, pp. 361-365
-
-
Crosetto, N.1
-
10
-
-
84927514894
-
Vivo genome editing using Staphylococcus aureus Cas9
-
Ran, F. A., et al. In vivo genome editing using Staphylococcus aureus Cas9. Nature 520, 186-191 (2015).
-
(2015)
Nature
, vol.520
, pp. 186-191
-
-
Ran, F.A.1
-
11
-
-
84952943845
-
Rationally engineered Cas9 nucleases with improved specificity
-
Slaymaker, I. M., et al. Rationally engineered Cas9 nucleases with improved specificity. Science 351, 84-88 (2016).
-
(2016)
Science
, vol.351
, pp. 84-88
-
-
Slaymaker, I.M.1
-
12
-
-
84923266604
-
Guide-seq enables genome-wide profiling of off-Target cleavage by crispr-cas nucleases
-
Tsai, S. Q., et al. GUIDE-seq enables genome-wide profiling of off-Target cleavage by CRISPR-Cas nucleases. Nat. Biotechnol. 33, 187-197 (2015).
-
(2015)
Nat. Biotechnol
, vol.33
, pp. 187-197
-
-
Tsai, S.Q.1
-
13
-
-
84923846574
-
Digenome-seq: Genome-wide profiling of CRISPR-Cas9 off-Target effects in human cells
-
Kim, D., et al. Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-Target effects in human cells. Nat. Methods 12, 237-243 (2015).
-
(2015)
Nat. Methods
, vol.12
, pp. 237-243
-
-
Kim, D.1
-
14
-
-
84923221641
-
Unbiased detection of off-Target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors
-
Wang, X., et al. Unbiased detection of off-Target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors. Nat. Biotechnol. 33, 175-178 (2015).
-
(2015)
Nat. Biotechnol
, vol.33
, pp. 175-178
-
-
Wang, X.1
-
15
-
-
84923275611
-
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases
-
Frock, R. L., et al. Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases. Nat. Biotechnol. 33, 179-186 (2015).
-
(2015)
Nat. Biotechnol
, vol.33
, pp. 179-186
-
-
Frock, R.L.1
-
16
-
-
84979730121
-
DNA breaks and end resection measured genome-wide by end sequencing
-
Canela, A., et al. DNA breaks and end resection measured genome-wide by end sequencing. Mol. Cell 63, 898-911 (2016).
-
(2016)
Mol. Cell
, vol.63
, pp. 898-911
-
-
Canela, A.1
-
17
-
-
84982102731
-
DSBCapture: In situ capture and sequencing of DNA breaks
-
Lensing, S. V., et al. DSBCapture: in situ capture and sequencing of DNA breaks. Nat. Methods 13, 855-857 (2016).
-
(2016)
Nat. Methods
, vol.13
, pp. 855-857
-
-
Lensing, S.V.1
-
18
-
-
85019234202
-
Breaks labeling in situ and sequencing (BLISS) Protocol Exchange
-
Winston, X. Y., et al. Breaks labeling in situ and sequencing (BLISS) Protocol Exchange. Protocol Exchange doi: 10.1038/protex.2017.018 (2017).
-
(2017)
Protocol Exchange
-
-
Winston, X.Y.1
-
19
-
-
84856484968
-
Counting absolute numbers of molecules using unique molecular identifiers
-
Kivioja, T., et al. Counting absolute numbers of molecules using unique molecular identifiers. Nat. Methods 9, 72-74 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 72-74
-
-
Kivioja, T.1
-
20
-
-
0025257556
-
Amplified RNA synthesized from limited quantities of heterogeneous cDNA
-
Van Gelder, R. N., et al. Amplified RNA synthesized from limited quantities of heterogeneous cDNA. Proc. Natl Acad. Sci. USA 87, 1663-1667 (1990).
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 1663-1667
-
-
Van Gelder, R.N.1
-
21
-
-
84866953427
-
CEL-Seq single-cell RNA-Seq by multiplexed linear amplification
-
Hashimshony, T., Wagner, F., Sher, N., & Yanai, I. CEL-Seq: single-cell RNA-Seq by multiplexed linear amplification. Cell Rep. 2, 666-673 (2012).
-
(2012)
Cell Rep
, vol.2
, pp. 666-673
-
-
Hashimshony, T.1
Wagner, F.2
Sher, N.3
Yanai, I.4
-
22
-
-
84922333547
-
Anthracyclines induce double-strand DNA breaks at active gene promoters
-
Yang, F., Kemp, C. J., & Henikoffa, S. Anthracyclines induce double-strand DNA breaks at active gene promoters. Mutat. Res. 773, 9-15 (2015).
-
(2015)
Mutat. Res
, vol.773
, pp. 9-15
-
-
Yang, F.1
Kemp, C.J.2
Henikoffa, S.3
-
23
-
-
84975678715
-
Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system
-
Zetsche, B., et al. Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system. Cell 163, 759-771 (2015).
-
(2015)
Cell
, vol.163
, pp. 759-771
-
-
Zetsche, B.1
-
24
-
-
84896308706
-
Cas-OFFinder a fast and versatile algorithm that searches for potential off-Target sites of Cas9 RNA-guided endonucleases
-
Bae, S., Park, J., & Kim, J.-S. Cas-OFFinder: a fast and versatile algorithm that searches for potential off-Target sites of Cas9 RNA-guided endonucleases. Bioinformatics 30, 1473-1475 (2014).
-
(2014)
Bioinformatics
, vol.30
, pp. 1473-1475
-
-
Bae, S.1
Park, J.2
Kim, J.-S.3
-
25
-
-
84981318543
-
Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells
-
Kim, D., et al. Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells. Nat. Biotechnol. 34, 863-868 (2016).
-
(2016)
Nat. Biotechnol
, vol.34
, pp. 863-868
-
-
Kim, D.1
-
26
-
-
84981347695
-
Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
-
Kleinstiver, B. P., et al. Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells. Nat. Biotechnol. 34, 869-874 (2016).
-
(2016)
Nat. Biotechnol
, vol.34
, pp. 869-874
-
-
Kleinstiver, B.P.1
-
27
-
-
84884165315
-
DNA targeting specificity of RNA-guided Cas9 nucleases
-
Hsu, P. D., et al. DNA targeting specificity of RNA-guided Cas9 nucleases. Nat. Biotechnol. 31, 827-832 (2013).
-
(2013)
Nat. Biotechnol
, vol.31
, pp. 827-832
-
-
Hsu, P.D.1
|