Dapagliflozin modulates glucagon secretion in an SGLT2-independent manner in murine alpha cells

Diabetes and Metabolism

Volumn 43, Issue 6, 2017, Pages 512-520

  Solini, A ^a   Sebastiani, G ^b   Nigi, L ^b   Santini, E ^a   Rossi, C ^a   Dotta, F ^b  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

Author keywords

Alpha cells; Glucagon; SGLT1; SGLT2 inhibitors

Indexed keywords

CHROMOGRANIN A; DAPAGLIFLOZIN; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; HEPATOCYTE NUCLEAR FACTOR 4; PREPROGLUCAGON; PROPROTEIN CONVERTASE 1; SMALL INTERFERING RNA; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM GLUCOSE COTRANSPORTER 2; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR PAX6; 2-(3-(4-ETHOXYBENZYL)-4-CHLOROPHENYL)-6-HYDROXYMETHYLTETRAHYDRO-2H-PYRAN-3,4,5-TRIOL; BENZHYDRYL DERIVATIVE; GLUCOSE; GLUCOSIDE; SOMATOSTATIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE SILENCING; GENETIC TRANSFECTION; GLUCAGON RELEASE; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACELLULAR SIGNALING; LASER CAPTURE MICRODISSECTION; LIPID METABOLISM; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET ALPHA CELL; PROTEIN EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL LINE; DRUG EFFECT; GENETICS; METABOLISM; SECRETION (PROCESS); SIGNAL PROCESSING;

ANIMALS; BENZHYDRYL COMPOUNDS; CELL LINE; CELLS, CULTURED; GENE SILENCING; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; GLUCAGON-SECRETING CELLS; GLUCOSE; GLUCOSIDES; HUMANS; MICE; SIGNAL PROCESSING, COMPUTER-ASSISTED; SODIUM-GLUCOSE TRANSPORTER 1; SODIUM-GLUCOSE TRANSPORTER 2; SOMATOSTATIN;

EID: 85019123808     PISSN: 12623636     EISSN: 18781780     Source Type: Journal    
DOI: 10.1016/j.diabet.2017.04.002     Document Type: Article

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