Short-term diabetic hyperglycemia suppresses celiac ganglia neurotransmission, thereby impairing sympathetically mediated glucagon responses

American Journal of Physiology - Endocrinology and Metabolism

Volumn 309, Issue 3, 2015, Pages E246-E255

  Mundinger, Thomas O ^a   Cooper, Ellis ^b   Coleman, Michael P ^c   Taborsky, Gerald J ^a,d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b MCGILL UNIVERSITY   (Canada)

^c BABRAHAM INSTITUTE   (United Kingdom)

^d VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

Author keywords

Celiac ganglia; Fos; Glucagon; Nicotinic acetylcholine receptors; Norepinephrine; Sympathetic nervous system; WLDS

Indexed keywords

GLUCAGON; MESSENGER RNA; NICOTINE; NICOTINIC RECEPTOR; NORADRENALIN; PROTEIN FOS; SODIUM CHLORIDE; STREPTOZOCIN; GANGLION STIMULATING AGENT; MUTANT PROTEIN; NERVE PROTEIN; NICOTINIC AGENT; PROTEIN C FOS; WLD PROTEIN, RAT;

ADRENERGIC SYSTEM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELIAC GANGLION; CONTROLLED STUDY; DIABETES MELLITUS; HORMONE RESPONSE; HYPERGLYCEMIA; MALE; NERVE STIMULATION; NEUROTRANSMISSION; NONHUMAN; PANCREAS ISLET CELL; PREGANGLIONIC NERVE; PRIORITY JOURNAL; RAT; ANIMAL; BLOOD; CHEMISTRY; COMPLICATION; DOWN REGULATION; DRUG EFFECTS; ELECTROSTIMULATION; GENETICS; INNERVATION; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; NERVE CELL; PANCREAS ISLET; PATHOPHYSIOLOGY; SECRETION (PROCESS); SPRAGUE DAWLEY RAT; SYMPATHETIC GANGLION; SYNAPTIC TRANSMISSION; TRANSGENIC RAT; WALLERIAN DEGENERATION; WISTAR RAT;

ANIMALS; DIABETES MELLITUS, TYPE 1; DOWN-REGULATION; ELECTRIC STIMULATION; GANGLIA, SYMPATHETIC; GANGLIONIC STIMULANTS; GLUCAGON; HYPERGLYCEMIA; ISLETS OF LANGERHANS; MALE; MUTANT PROTEINS; NERVE TISSUE PROTEINS; NEURONS; NICOTINIC AGONISTS; NOREPINEPHRINE; PROTO-ONCOGENE PROTEINS C-FOS; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; RATS, WISTAR; RECEPTORS, NICOTINIC; SYNAPTIC TRANSMISSION; WALLERIAN DEGENERATION;

EID: 84938634731     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00140.2015     Document Type: Article

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