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Volumn 543, Issue 7647, 2017, Pages 723-727

Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD4 ANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TUMOR ANTIGEN; EPITOPE; HLA ANTIGEN CLASS 1; HLA D ANTIGEN; IMMUNOGLOBULIN VARIABLE REGION;

EID: 85018926405     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature21433     Document Type: Article
Times cited : (210)

References (63)
  • 1
    • 84880276438 scopus 로고    scopus 로고
    • Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
    • Robbins, P. F. et al. Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells. Nature Med. 19, 747-752 (2013).
    • (2013) Nature Med. , vol.19 , pp. 747-752
    • Robbins, P.F.1
  • 2
    • 84961323160 scopus 로고    scopus 로고
    • High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
    • Linnemann, C. et al. High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma. Nature Med. 21, 81-85 (2015).
    • (2015) Nature Med. , vol.21 , pp. 81-85
    • Linnemann, C.1
  • 3
    • 84900301377 scopus 로고    scopus 로고
    • Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer
    • Tran, E. et al. Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer. Science 344, 641-645 (2014).
    • (2014) Science , vol.344 , pp. 641-645
    • Tran, E.1
  • 4
    • 84872841412 scopus 로고    scopus 로고
    • Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma
    • van Rooij, N. et al. Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma. J. Clin. Oncol. 31, e439-e442 (2013).
    • (2013) J. Clin. Oncol. , vol.31 , pp. e439-e442
    • Van Rooij, N.1
  • 5
    • 84904472602 scopus 로고    scopus 로고
    • Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia
    • Rajasagi, M. et al. Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia. Blood 124, 453-462 (2014).
    • (2014) Blood , vol.124 , pp. 453-462
    • Rajasagi, M.1
  • 6
    • 84901618283 scopus 로고    scopus 로고
    • Tumor antigen discovery through translation of the cancer genome
    • Khodadoust, M. S. & Alizadeh, A. A. Tumor antigen discovery through translation of the cancer genome. Immunol. Res. 58, 292-299 (2014).
    • (2014) Immunol. Res. , vol.58 , pp. 292-299
    • Khodadoust, M.S.1    Alizadeh, A.A.2
  • 7
    • 84928811341 scopus 로고    scopus 로고
    • Mutant MHC class II epitopes drive therapeutic immune responses to cancer
    • Kreiter, S. et al. Mutant MHC class II epitopes drive therapeutic immune responses to cancer. Nature 520, 692-696 (2015).
    • (2015) Nature , vol.520 , pp. 692-696
    • Kreiter, S.1
  • 8
    • 84920998525 scopus 로고    scopus 로고
    • HLA ligandome analysis identifies the underlying specificities of spontaneous antileukemia immune responses in chronic lymphocytic leukemia (CLL)
    • Kowalewski, D. J. et al. HLA ligandome analysis identifies the underlying specificities of spontaneous antileukemia immune responses in chronic lymphocytic leukemia (CLL). Proc. Natl Acad. Sci. USA 112, E166-E175 (2015).
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. E166-E175
    • Kowalewski, D.J.1
  • 9
    • 84924352568 scopus 로고    scopus 로고
    • Mapping the HLA ligandome landscape of acute myeloid leukemia: A targeted approach toward peptide-based immunotherapy
    • Berlin, C. et al. Mapping the HLA ligandome landscape of acute myeloid leukemia: a targeted approach toward peptide-based immunotherapy. Leukemia 29, 647-659 (2015).
    • (2015) Leukemia , vol.29 , pp. 647-659
    • Berlin, C.1
  • 10
    • 84860209098 scopus 로고    scopus 로고
    • Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy
    • Dutoit, V. et al. Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy. Brain 135, 1042-1054 (2012).
    • (2012) Brain , vol.135 , pp. 1042-1054
    • Dutoit, V.1
  • 11
    • 84958064376 scopus 로고    scopus 로고
    • Use of HLA peptidomics and whole exome sequencing to identify human immunogenic neo-antigens
    • Kalaora, S. et al. Use of HLA peptidomics and whole exome sequencing to identify human immunogenic neo-antigens. Oncotarget 7, 5110-5117 (2016).
    • (2016) Oncotarget , vol.7 , pp. 5110-5117
    • Kalaora, S.1
  • 12
    • 84995916390 scopus 로고    scopus 로고
    • Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry
    • Bassani-Sternberg, M. et al. Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry. Nature Commun. 7, 13404 (2016).
    • (2016) Nature Commun. , vol.7 , pp. 13404
    • Bassani-Sternberg, M.1
  • 13
    • 84920956731 scopus 로고    scopus 로고
    • Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
    • Yadav, M. et al. Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature 515, 572-576 (2014).
    • (2014) Nature , vol.515 , pp. 572-576
    • Yadav, M.1
  • 14
    • 84942525157 scopus 로고    scopus 로고
    • The antigenic landscape of multiple myeloma: Mass spectrometry (re)defines targets for T-cell-based immunotherapy
    • Walz, S. et al. The antigenic landscape of multiple myeloma: mass spectrometry (re)defines targets for T-cell-based immunotherapy. Blood 126, 1203-1213 (2015).
    • (2015) Blood , vol.126 , pp. 1203-1213
    • Walz, S.1
  • 15
    • 84876460347 scopus 로고    scopus 로고
    • Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma
    • Green, M. R. et al. Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma. Blood 121, 1604-1611 (2013).
    • (2013) Blood , vol.121 , pp. 1604-1611
    • Green, M.R.1
  • 16
    • 84924308788 scopus 로고    scopus 로고
    • Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation
    • Green, M. R. et al. Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation. Proc. Natl Acad. Sci. USA 112, E1116-E1125 (2015).
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. E1116-E1125
    • Green, M.R.1
  • 17
    • 84897523438 scopus 로고    scopus 로고
    • Cyclin D1 transcriptional activation in MCL
    • Beà, S. Cyclin D1 transcriptional activation in MCL. Blood 123, 1979-1980 (2014).
    • (2014) Blood , vol.123 , pp. 1979-1980
    • Beà, S.1
  • 18
    • 84903182870 scopus 로고    scopus 로고
    • The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells
    • Zhang, J. et al. The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells. Blood 123, 2988-2996 (2014).
    • (2014) Blood , vol.123 , pp. 2988-2996
    • Zhang, J.1
  • 19
    • 84887285547 scopus 로고    scopus 로고
    • Landscape of somatic mutations and clonal evolution in mantle cell lymphoma
    • Beà, S. et al. Landscape of somatic mutations and clonal evolution in mantle cell lymphoma. Proc. Natl Acad. Sci. USA 110, 18250-18255 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 18250-18255
    • Beà, S.1
  • 20
    • 84857763426 scopus 로고    scopus 로고
    • Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma
    • Kridel, R. et al. Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma. Blood 119, 1963-1971 (2012).
    • (2012) Blood , vol.119 , pp. 1963-1971
    • Kridel, R.1
  • 21
    • 84899748384 scopus 로고    scopus 로고
    • PD-1 identifies the patient-specific CD8+ tumor-reactive repertoire infiltrating human tumors
    • Gros, A. et al. PD-1 identifies the patient-specific CD8+ tumor-reactive repertoire infiltrating human tumors. J. Clin. Invest. 124, 2246-2259 (2014).
    • (2014) J. Clin. Invest. , vol.124 , pp. 2246-2259
    • Gros, A.1
  • 22
    • 84903993800 scopus 로고    scopus 로고
    • Linking T-cell receptor sequence to functional phenotype at the single-cell level
    • Han, A., Glanville, J., Hansmann, L. & Davis, M. M. Linking T-cell receptor sequence to functional phenotype at the single-cell level. Nature Biotechnol. 32, 684-692 (2014).
    • (2014) Nature Biotechnol. , vol.32 , pp. 684-692
    • Han, A.1    Glanville, J.2    Hansmann, L.3    Davis, M.M.4
  • 23
    • 77949522803 scopus 로고    scopus 로고
    • Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
    • Quezada, S. A. et al. Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts. J. Exp. Med. 207, 637-650 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 637-650
    • Quezada, S.A.1
  • 24
    • 0034125194 scopus 로고    scopus 로고
    • Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies
    • Trojan, A. et al. Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies. Nature Med. 6, 667-672 (2000).
    • (2000) Nature Med. , vol.6 , pp. 667-672
    • Trojan, A.1
  • 25
    • 77956608707 scopus 로고    scopus 로고
    • Comparative analysis of predicted HLA binding of immunoglobulin idiotype sequences indicates T cell-mediated immunosurveillance in follicular lymphoma
    • Strothmeyer, A. M. et al. Comparative analysis of predicted HLA binding of immunoglobulin idiotype sequences indicates T cell-mediated immunosurveillance in follicular lymphoma. Blood 116, 1734-1736 (2010).
    • (2010) Blood , vol.116 , pp. 1734-1736
    • Strothmeyer, A.M.1
  • 26
    • 34249000978 scopus 로고    scopus 로고
    • Lymphomas can develop from B cells chronically helped by idiotype-specific T cells
    • Zangani, M. M. et al. Lymphomas can develop from B cells chronically helped by idiotype-specific T cells. J. Exp. Med. 204, 1181-1191 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 1181-1191
    • Zangani, M.M.1
  • 27
    • 0026793994 scopus 로고
    • Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumors
    • Kwak, L. W. et al. Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumors. N. Engl. J. Med. 327, 1209-1215 (1992).
    • (1992) N. Engl. J. Med. , vol.327 , pp. 1209-1215
    • Kwak, L.W.1
  • 28
    • 24744457075 scopus 로고    scopus 로고
    • Vaccine-induced tumor-specific immunity despite severe B-cell depletion in mantle cell lymphoma
    • Neelapu, S. S. et al. Vaccine-induced tumor-specific immunity despite severe B-cell depletion in mantle cell lymphoma. Nature Med. 11, 986-991 (2005).
    • (2005) Nature Med. , vol.11 , pp. 986-991
    • Neelapu, S.S.1
  • 29
    • 67649961713 scopus 로고    scopus 로고
    • Placebo-controlled phase III trial of patient-specific immunotherapy with mitumprotimut-T and granulocyte-macrophage colony-stimulating factor after rituximab in patients with follicular lymphoma
    • Freedman, A. et al. Placebo-controlled phase III trial of patient-specific immunotherapy with mitumprotimut-T and granulocyte-macrophage colony-stimulating factor after rituximab in patients with follicular lymphoma. J. Clin. Oncol. 27, 3036-3043 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , pp. 3036-3043
    • Freedman, A.1
  • 30
    • 84905841445 scopus 로고    scopus 로고
    • Active idiotypic vaccination versus control immunotherapy for follicular lymphoma
    • Levy, R. et al. Active idiotypic vaccination versus control immunotherapy for follicular lymphoma. J. Clin. Oncol. 32, 1797-1803 (2014).
    • (2014) J. Clin. Oncol. , vol.32 , pp. 1797-1803
    • Levy, R.1
  • 31
    • 79958264390 scopus 로고    scopus 로고
    • Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma
    • Schuster, S. J. et al. Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma. J. Clin. Oncol. 29, 2787-2794 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , pp. 2787-2794
    • Schuster, S.J.1
  • 32
    • 84943516465 scopus 로고    scopus 로고
    • Genomic correlates of response to CTLA-4 blockade in metastatic melanoma
    • Van Allen, E. M. et al. Genomic correlates of response to CTLA-4 blockade in metastatic melanoma. Science 350, 207-211 (2015).
    • (2015) Science , vol.350 , pp. 207-211
    • Van Allen, E.M.1
  • 33
    • 84928761118 scopus 로고    scopus 로고
    • Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
    • Rizvi, N. A. et al. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science 348, 124-128 (2015).
    • (2015) Science , vol.348 , pp. 124-128
    • Rizvi, N.A.1
  • 34
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • Li, H. & Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754-1760 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 35
    • 84863229597 scopus 로고    scopus 로고
    • VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
    • Koboldt, D. C. et al. VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Res. 22, 568-576 (2012).
    • (2012) Genome Res. , vol.22 , pp. 568-576
    • Koboldt, D.C.1
  • 36
    • 84896321422 scopus 로고    scopus 로고
    • Using VarScan 2 for germline variant calling and somatic mutation detection
    • Koboldt, D. C., Larson, D. E. & Wilson, R. K. Using VarScan 2 for germline variant calling and somatic mutation detection. Curr. Protoc. Bioinformatics 44, 15.14.1-15.14.17 (2013).
    • (2013) Curr. Protoc. Bioinformatics , vol.44 , pp. 15141-151417
    • Koboldt, D.C.1    Larson, D.E.2    Wilson, R.K.3
  • 37
    • 77956534324 scopus 로고    scopus 로고
    • ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data
    • Wang, K., Li, M. & Hakonarson, H. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res. 38, e164 (2010).
    • (2010) Nucleic Acids Res. , vol.38 , pp. e164
    • Wang, K.1    Li, M.2    Hakonarson, H.3
  • 38
    • 84899920375 scopus 로고    scopus 로고
    • Inference of high resolution HLA types using genome-wide RNA or DNA sequencing reads
    • Bai, Y., Ni, M., Cooper, B., Wei, Y. & Fury, W. Inference of high resolution HLA types using genome-wide RNA or DNA sequencing reads. BMC Genomics 15, 325 (2014).
    • (2014) BMC Genomics , vol.15 , pp. 325
    • Bai, Y.1    Ni, M.2    Cooper, B.3    Wei, Y.4    Fury, W.5
  • 39
    • 48449106045 scopus 로고    scopus 로고
    • NetMHC-3.0: Accurate web accessible predictions of human, mouse and monkey MHC class i affinities for peptides of length 8-11
    • Lundegaard, C. et al. NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11. Nucleic Acids Res. 36, W509-W512 (2008).
    • (2008) Nucleic Acids Res. , vol.36 , pp. W509-W512
    • Lundegaard, C.1
  • 40
    • 39549084433 scopus 로고    scopus 로고
    • NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and-B locus protein of known sequence
    • Nielsen, M. et al. NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and-B locus protein of known sequence. PLoS ONE 2, e796 (2007).
    • (2007) PLoS ONE , vol.2 , pp. e796
    • Nielsen, M.1
  • 41
    • 9144265458 scopus 로고    scopus 로고
    • Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936
    • van Dongen, J. J. et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 17, 2257-2317 (2003).
    • (2003) Leukemia , vol.17 , pp. 2257-2317
    • Van Dongen, J.J.1
  • 42
    • 0032918724 scopus 로고    scopus 로고
    • IMGT, the international ImMunoGeneTics database
    • Lefranc, M. P. et al. IMGT, the international ImMunoGeneTics database. Nucleic Acids Res. 27, 209-212 (1999).
    • (1999) Nucleic Acids Res. , vol.27 , pp. 209-212
    • Lefranc, M.P.1
  • 43
    • 33847630405 scopus 로고    scopus 로고
    • Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry
    • Elias, J. E. & Gygi, S. P. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. Nature Methods 4, 207-214 (2007).
    • (2007) Nature Methods , vol.4 , pp. 207-214
    • Elias, J.E.1    Gygi, S.P.2
  • 44
    • 0026507564 scopus 로고
    • Characterization of peptides bound to the class i MHC molecule HLA-A2.1 by mass spectrometry
    • Hunt, D. F. et al. Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. Science 255, 1261-1263 (1992).
    • (1992) Science , vol.255 , pp. 1261-1263
    • Hunt, D.F.1
  • 45
    • 0026664454 scopus 로고
    • Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad
    • Hunt, D. F. et al. Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad. Science 256, 1817-1820 (1992).
    • (1992) Science , vol.256 , pp. 1817-1820
    • Hunt, D.F.1
  • 46
    • 0018154865 scopus 로고
    • Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis
    • Barnstable, C. J. et al. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell 14, 9-20 (1978).
    • (1978) Cell , vol.14 , pp. 9-20
    • Barnstable, C.J.1
  • 47
    • 0018937455 scopus 로고
    • Two populations of Ia-like molecules on a human B cell line
    • Lampson, L. A. & Levy, R. Two populations of Ia-like molecules on a human B cell line. J. Immunol. 125, 293-299 (1980).
    • (1980) J. Immunol. , vol.125 , pp. 293-299
    • Lampson, L.A.1    Levy, R.2
  • 48
    • 0037317228 scopus 로고    scopus 로고
    • Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics
    • Rappsilber, J., Ishihama, Y. & Mann, M. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. Anal. Chem. 75, 663-670 (2003).
    • (2003) Anal. Chem. , vol.75 , pp. 663-670
    • Rappsilber, J.1    Ishihama, Y.2    Mann, M.3
  • 49
    • 0000857494 scopus 로고
    • An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database
    • Eng, J. K., McCormack, A. L. & Yates, J. R. An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J. Am. Soc. Mass Spectrom. 5, 976-989 (1994).
    • (1994) J. Am. Soc. Mass Spectrom. , vol.5 , pp. 976-989
    • Eng, J.K.1    McCormack, A.L.2    Yates, J.R.3
  • 50
    • 84859826519 scopus 로고    scopus 로고
    • PEAKS DB: De novo sequencing assisted database search for sensitive and accurate peptide identification
    • Zhang, J. et al. PEAKS DB: de novo sequencing assisted database search for sensitive and accurate peptide identification. Mol. Cell Proteom. 11, M111.010587 (2012).
    • (2012) Mol. Cell Proteom. , vol.11
    • Zhang, J.1
  • 51
    • 35748972060 scopus 로고    scopus 로고
    • Semisupervised learning for peptide identification from shotgun proteomics datasets
    • Käll, L., Canterbury, J. D., Weston, J., Noble, W. S. & MacCoss, M. J. Semisupervised learning for peptide identification from shotgun proteomics datasets. Nature Methods 4, 923-925 (2007).
    • (2007) Nature Methods , vol.4 , pp. 923-925
    • Käll, L.1    Canterbury, J.D.2    Weston, J.3    Noble, W.S.4    MacCoss, M.J.5
  • 53
    • 84946076702 scopus 로고    scopus 로고
    • The immune epitope database (IEDB) 3.0
    • Vita, R. et al. The immune epitope database (IEDB) 3.0. Nucleic Acids Res. 43, D405-D412 (2015).
    • (2015) Nucleic Acids Res. , vol.43 , pp. D405-D412
    • Vita, R.1
  • 54
    • 26444539668 scopus 로고    scopus 로고
    • Orthogonality of separation in two-dimensional liquid chromatography
    • Gilar, M., Olivova, P., Daly, A. E. & Gebler, J. C. Orthogonality of separation in two-dimensional liquid chromatography. Anal. Chem. 77, 6426-6434 (2005).
    • (2005) Anal. Chem. , vol.77 , pp. 6426-6434
    • Gilar, M.1    Olivova, P.2    Daly, A.E.3    Gebler, J.C.4
  • 55
    • 79955752894 scopus 로고    scopus 로고
    • Reversed-phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells
    • Wang, Y. et al. Reversed-phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells. Proteomics 11, 2019-2026 (2011).
    • (2011) Proteomics , vol.11 , pp. 2019-2026
    • Wang, Y.1
  • 56
    • 84910081742 scopus 로고    scopus 로고
    • A proteomic ruler for protein copy number and concentration estimation without spike-in standards
    • Wisniewski, J. R., Hein, M. Y., Cox, J. & Mann, M. A proteomic ruler for protein copy number and concentration estimation without spike-in standards. Mol. Cell. Proteomics 13, 3497-3506 (2014).
    • (2014) Mol. Cell. Proteomics , vol.13 , pp. 3497-3506
    • Wisniewski, J.R.1    Hein, M.Y.2    Cox, J.3    Mann, M.4
  • 57
    • 84976875034 scopus 로고    scopus 로고
    • PANTHER version 10: Expanded protein families and functions, and analysis tools
    • Mi, H., Poudel, S., Muruganujan, A., Casagrande, J. T. & Thomas, P. D. PANTHER version 10: expanded protein families and functions, and analysis tools. Nucleic Acids Res. 44 (D1), D336-D342 (2016).
    • (2016) Nucleic Acids Res. , vol.44 , Issue.D1 , pp. D336-D342
    • Mi, H.1    Poudel, S.2    Muruganujan, A.3    Casagrande, J.T.4    Thomas, P.D.5
  • 58
    • 0142155578 scopus 로고    scopus 로고
    • Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers
    • Day, C. L. et al. Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers. J. Clin. Invest. 112, 831-842 (2003).
    • (2003) J. Clin. Invest. , vol.112 , pp. 831-842
    • Day, C.L.1
  • 59
    • 84943610604 scopus 로고    scopus 로고
    • TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL
    • Kirsch, I. R. et al. TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL. Sci. Transl. Med. 7, 308ra158 (2015).
    • (2015) Sci. Transl. Med. , vol.7 , pp. 308ra158
    • Kirsch, I.R.1
  • 60
    • 58149316094 scopus 로고    scopus 로고
    • IMGT, the international ImMunoGeneTics information system
    • Lefranc, M. P. et al. IMGT, the international ImMunoGeneTics information system. Nucleic Acids Res. 37, D1006-D1012 (2009).
    • (2009) Nucleic Acids Res. , vol.37 , pp. D1006-D1012
    • Lefranc, M.P.1
  • 61
    • 34347266953 scopus 로고    scopus 로고
    • Generation of peptide-MHC class i complexes through UV-mediated ligand exchange
    • Rodenko, B. et al. Generation of peptide-MHC class I complexes through UV-mediated ligand exchange. Nature Protocols 1, 1120-1132 (2006).
    • (2006) Nature Protocols , vol.1 , pp. 1120-1132
    • Rodenko, B.1
  • 62
    • 0037407113 scopus 로고    scopus 로고
    • Reliable prediction of T-cell epitopes using neural networks with novel sequence representations
    • Nielsen, M. et al. Reliable prediction of T-cell epitopes using neural networks with novel sequence representations. Protein Sci. 12, 1007-1017 (2003).
    • (2003) Protein Sci. , vol.12 , pp. 1007-1017
    • Nielsen, M.1
  • 63
    • 67649610665 scopus 로고    scopus 로고
    • Simultaneous detection of many T-cell specificities using combinatorial tetramer staining
    • Newell, E. W., Klein, L. O., Yu, W. & Davis, M. M. Simultaneous detection of many T-cell specificities using combinatorial tetramer staining. Nature Methods 6, 497-499 (2009).
    • (2009) Nature Methods , vol.6 , pp. 497-499
    • Newell, E.W.1    Klein, L.O.2    Yu, W.3    Davis, M.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.