메뉴 건너뛰기




Volumn 58, Issue 2-3, 2014, Pages 292-299

Tumor antigen discovery through translation of the cancer genome

Author keywords

Antigenome; Cancer immunology; Immunome; Mutated antigen; Neoantigen

Indexed keywords

IMMUNOMODULATING AGENT; MAJOR HISTOCOMPATIBILITY ANTIGEN; TUMOR ANTIGEN;

EID: 84901618283     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-014-8505-4     Document Type: Review
Times cited : (11)

References (84)
  • 1
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366(26):2455-65.
    • (2012) N Engl J Med , vol.366 , Issue.26 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3    Hwu, W.J.4    Topalian, S.L.5    Hwu, P.6
  • 2
    • 84879759020 scopus 로고    scopus 로고
    • Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
    • Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med. 2013;369(2):134-44.
    • (2013) N Engl J Med , vol.369 , Issue.2 , pp. 134-144
    • Hamid, O.1    Robert, C.2    Daud, A.3    Hodi, F.S.4    Hwu, W.J.5    Kefford, R.6
  • 3
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermottDF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366(26):2443-54.
    • (2012) N Engl J Med , vol.366 , Issue.26 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3    Gettinger, S.N.4    Smith, D.C.M.5
  • 6
    • 84862882003 scopus 로고    scopus 로고
    • Tumor immunotherapy directed at PD-1
    • Ribas A. Tumor immunotherapy directed at PD-1. N Engl J Med. 2012;366(26):2517-9.
    • (2012) N Engl J Med , vol.366 , Issue.26 , pp. 2517-2519
    • Ribas, A.1
  • 7
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
    • Wolchok JD, Hoos A, O'Day S, Weber JS, Hamid O, Lebbe C, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res. 2009;15(23):7412-20.
    • (2009) Clin Cancer Res , vol.15 , Issue.23 , pp. 7412-7420
    • Wolchok, J.D.1    Hoos, A.2    O'Day, S.3    Weber, J.S.4    Hamid, O.5    Lebbe, C.6
  • 8
    • 69049089548 scopus 로고    scopus 로고
    • The prioritization of cancer antigens: A national cancer institute pilot project for the acceleration of translational research
    • Cheever MA, Allison JP, Ferris AS, Finn OJ, Hastings BM, Hecht TT, et al. The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research. Clin Cancer Res. 2009;15(17):5323-37.
    • (2009) Clin Cancer Res , vol.15 , Issue.17 , pp. 5323-5337
    • Cheever, M.A.1    Allison, J.P.2    Ferris, A.S.3    Finn, O.J.4    Hastings, B.M.5    Hecht, T.T.6
  • 10
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • DOI 10.1038/nm1100
    • Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat Med. 2004;10(9):909-15. (Pubitemid 39273730)
    • (2004) Nature Medicine , vol.10 , Issue.9 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 14
    • 33749023052 scopus 로고    scopus 로고
    • Unique tumor antigens: Evidence for immune control of genome integrity and immunogenic targets for T Cell - Mediated patient-specific immunotherapy
    • DOI 10.1158/1078-0432.CCR-05-2682
    • Sensi M, Anichini A. Unique tumor antigens: evidence for immune control of genome integrity and immunogenic targets for T cell-mediated patient-specific immunotherapy. Clin Cancer Res. 2006;12(17):5023-32. (Pubitemid 44453327)
    • (2006) Clinical Cancer Research , vol.12 , Issue.17 , pp. 5023-5032
    • Sensi, M.1    Anichini, A.2
  • 15
    • 84886075487 scopus 로고    scopus 로고
    • HLA ligandome tumor antigen discovery for personalized vaccine approach
    • Rammensee HG, Singh-Jasuja H. HLA ligandome tumor antigen discovery for personalized vaccine approach. Expert Rev Vaccines. 2013;12(10):1211-7.
    • (2013) Expert Rev Vaccines , vol.12 , Issue.10 , pp. 1211-1217
    • Rammensee, H.G.1    Singh-Jasuja, H.2
  • 17
    • 84886944933 scopus 로고    scopus 로고
    • TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients
    • Kvistborg P, Shu CJ, Heemskerk B, Fankhauser M, Thrue CA, Toebes M, et al. TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients. Oncoimmunology. 2012;1(4):409-18.
    • (2012) Oncoimmunology , vol.1 , Issue.4 , pp. 409-418
    • Kvistborg, P.1    Shu, C.J.2    Heemskerk, B.3    Fankhauser, M.4    Thrue, C.A.5    Toebes, M.6
  • 18
    • 0001739064 scopus 로고
    • Intradermal immunization of C3H mice against a sarcoma that originated in an animal of the same line
    • Gross L. Intradermal immunization of C3H mice against a sarcoma that originated in an animal of the same line. Cancer Res. 1943;3(5):326-33.
    • (1943) Cancer Res , vol.3 , Issue.5 , pp. 326-333
    • Gross, L.1
  • 19
    • 84965157146 scopus 로고
    • Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin
    • Foley EJ. Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin. Cancer Res. 1953;13(12):835-7.
    • (1953) Cancer Res , vol.13 , Issue.12 , pp. 835-837
    • Foley, E.J.1
  • 21
    • 0026793994 scopus 로고
    • Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumors
    • Kwak LW, Campbell MJ, Czerwinski DK, Hart S, Miller RA, Levy R. Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumors. N Engl J Med. 1992;327(17):1209-15.
    • (1992) N Engl J Med , vol.327 , Issue.17 , pp. 1209-1215
    • Kwak, L.W.1    Campbell, M.J.2    Czerwinski, D.K.3    Hart, S.4    Miller, R.A.5    Levy, R.6
  • 22
    • 67649961713 scopus 로고    scopus 로고
    • Placebo-controlled phase III trial of patientspecific immunotherapy with mitumprotimut-T and granulocytemacrophage colony-stimulating factor after rituximab in patients with follicular lymphoma
    • Freedman A, Neelapu SS, Nichols C, Robertson MJ, Djulbegovic B, Winter JN, et al. Placebo-controlled phase III trial of patientspecific immunotherapy with mitumprotimut-T and granulocytemacrophage colony-stimulating factor after rituximab in patients with follicular lymphoma. J Clin Oncol. 2009;27(18):3036-43.
    • (2009) J Clin Oncol , vol.27 , Issue.18 , pp. 3036-3043
    • Freedman, A.1    Neelapu, S.S.2    Nichols, C.3    Robertson, M.J.4    Djulbegovic, B.5    Winter, J.N.6
  • 23
    • 79958264390 scopus 로고    scopus 로고
    • Vaccination with patient-specific tumorderived antigen in first remission improves disease-free survival in follicular lymphoma
    • Schuster SJ, Neelapu SS, Gause BL, Janik JE, Muggia FM, Gockerman JP, et al. Vaccination with patient-specific tumorderived antigen in first remission improves disease-free survival in follicular lymphoma. J Clin Oncol. 2011;29(20):2787-94.
    • (2011) J Clin Oncol , vol.29 , Issue.20 , pp. 2787-2794
    • Schuster, S.J.1    Neelapu, S.S.2    Gause, B.L.3    Janik, J.E.4    Muggia, F.M.5    Gockerman, J.P.6
  • 24
    • 57749119753 scopus 로고    scopus 로고
    • Results of a Phase 3 trial evaluating safety and efficacy of specific immunotherapy, recombinant idiotype (Id) conjugated to KLH (Id-KLH) with GM-CSF, compared to non-specific immunotherapy, KLH with GM-CSF, in patients with follicular non-Hodgkin's lymphoma (fNHL)
    • San Diego, CA: AACR
    • Levy R, Robertson M, Ganjoo K, JP L, J V, D D, editors. Results of a Phase 3 trial evaluating safety and efficacy of specific immunotherapy, recombinant idiotype (Id) conjugated to KLH (Id-KLH) with GM-CSF, compared to non-specific immunotherapy, KLH with GM-CSF, in patients with follicular non-Hodgkin's lymphoma (fNHL). Proceedings of the 99th Annual Meeting of the American Association for Cancer Research; 2008;San Diego, CA: AACR.
    • Proceedings of the 99th Annual Meeting of the American Association for Cancer Research; 2008
    • Levy, R.1    Robertson, M.2    Ganjoo, K.3    L, J.P.4    V, J.5    D, D.6
  • 25
    • 0024316157 scopus 로고
    • - transplantation antigen P91A: The mutated exon encodes a peptide recognized with L(d) by cytolytic T cells
    • DOI 10.1016/0092-8674(89)90844-1
    • Lurquin C, Van Pel A, Mariamé B, De Plaen E, Szikora JP, Janssens C, et al. Structure of the gene of tum- transplantation antigen P91A: the mutated exon encodes a peptide recognized with Ld by cytolytic T cells. Cell. 1989;58(2):293-303. (Pubitemid 19191412)
    • (1989) Cell , vol.58 , Issue.2 , pp. 293-303
    • Lurquin, C.1    Van Pel, A.2    Mariame, B.3    De Plaen, E.4    Szikora, J.-P.5    Janssens, C.6    Reddehase, M.J.7    Lejeune, J.8    Boon, T.9
  • 26
    • 0028978274 scopus 로고
    • A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma
    • Wölfel T, Hauer M, Schneider J, Serrano M, Wölfel C, Klehmann-Hieb E, et al. A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma. Science. 1995;269(5228):1281-4.
    • (1995) Science , vol.269 , Issue.5228 , pp. 1281-1284
    • Wölfel, T.1    Hauer, M.2    Schneider, J.3    Serrano, M.4    Wölfel, C.5    Klehmann-Hieb, E.6
  • 27
    • 0029125899 scopus 로고
    • A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma
    • Coulie PG, Lehmann F, Lethé B, Herman J, Lurquin C, Andrawiss M, et al. A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma. Proc Natl Acad Sci USA. 1995;92(17):7976-80.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.17 , pp. 7976-7980
    • Coulie, P.G.1    Lehmann, F.2    Lethé, B.3    Herman, J.4    Lurquin, C.5    Andrawiss, M.6
  • 28
    • 0029669950 scopus 로고    scopus 로고
    • A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes
    • Robbins PF, El-Gamil M, Li YF, Kawakami Y, Loftus D, Appella E, et al. A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes. J Exp Med. 1996;183(3):1185-92.
    • (1996) J Exp Med , vol.183 , Issue.3 , pp. 1185-1192
    • Robbins, P.F.1    El-Gamil, M.2    Li, Y.F.3    Kawakami, Y.4    Loftus, D.5    Appella, E.6
  • 29
    • 42549105195 scopus 로고    scopus 로고
    • Evaluation of MHC class I peptide binding prediction servers: Applications for vaccine research
    • Lin HH, Ray S, Tongchusak S, Reinherz EL, Brusic V. Evaluation of MHC class I peptide binding prediction servers: applications for vaccine research. BMC Immunol. 2008;9:8.
    • (2008) BMC Immunol , vol.9 , pp. 8
    • Lin, H.H.1    Ray, S.2    Tongchusak, S.3    Reinherz, E.L.4    Brusic, V.5
  • 31
    • 44349146151 scopus 로고    scopus 로고
    • Accurate approximation method for prediction of class I MHC affinities for peptides of length 8, 10 and 11 using prediction tools trained on 9mers
    • DOI 10.1093/bioinformatics/btn128
    • Lundegaard C, Lund O, Nielsen M. Accurate approximation method for prediction of class I MHC affinities for peptides of length 8, 10 and 11 using prediction tools trained on 9mers. Bioinformatics. 2008;24(11):1397-8. (Pubitemid 351737147)
    • (2008) Bioinformatics , vol.24 , Issue.11 , pp. 1397-1398
    • Lundegaard, C.1    Lund, O.2    Nielsen, M.3
  • 32
    • 34250196006 scopus 로고    scopus 로고
    • Strength in numbers: Achieving greater accuracy in MHC-I binding prediction by combining the results from multiple prediction tools
    • Trost B, Bickis M, Kusalik A. Strength in numbers: achieving greater accuracy in MHC-I binding prediction by combining the results from multiple prediction tools. Immunome Res. 2007;3:5.
    • (2007) Immunome Res , vol.3 , pp. 5
    • Trost, B.1    Bickis, M.2    Kusalik, A.3
  • 34
    • 84885735554 scopus 로고    scopus 로고
    • Mutational landscape and significance across 12 major cancer types
    • Kandoth C, McLellan MD, Vandin F, Ye K, Niu B, Lu C, et al. Mutational landscape and significance across 12 major cancer types. Nature. 2013;502(7471):333-9.
    • (2013) Nature , vol.502 , Issue.7471 , pp. 333-339
    • Kandoth, C.1    McLellan, M.D.2    Vandin, F.3    Ye, K.4    Niu, B.5    Lu, C.6
  • 35
    • 84880507665 scopus 로고    scopus 로고
    • Mutational heterogeneity in cancer and the search for new cancer-associated genes
    • Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, Sivachenko A, et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature. 2013;499(7457):214-8.
    • (2013) Nature , vol.499 , Issue.7457 , pp. 214-218
    • Lawrence, M.S.1    Stojanov, P.2    Polak, P.3    Kryukov, G.V.4    Cibulskis, K.5    Sivachenko, A.6
  • 36
    • 84866434919 scopus 로고    scopus 로고
    • Genomic landscape of non-small cell lung cancer in smokers and never-smokers
    • Govindan R, Ding L, Griffith M, Subramanian J, Dees ND, Kanchi KL, et al. Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell. 2012;150(6):1121-34.
    • (2012) Cell , vol.150 , Issue.6 , pp. 1121-1134
    • Govindan, R.1    Ding, L.2    Griffith, M.3    Subramanian, J.4    Dees, N.D.5    Kanchi, K.L.6
  • 37
    • 84878372012 scopus 로고    scopus 로고
    • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
    • Network CGAR
    • Network CGAR. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med. 2013;368(22):2059-74.
    • (2013) N Engl J Med , vol.368 , Issue.22 , pp. 2059-2074
  • 38
    • 85027946522 scopus 로고    scopus 로고
    • Exome sequencing identifies GRIN2A as frequently mutated in melanoma
    • Wei X, Walia V, Lin JC, Teer JK, Prickett TD, Gartner J, et al. Exome sequencing identifies GRIN2A as frequently mutated in melanoma. Nat Genet. 2011;43(5):442-6.
    • (2011) Nat Genet , vol.43 , Issue.5 , pp. 442-446
    • Wei, X.1    Walia, V.2    Lin, J.C.3    Teer, J.K.4    Prickett, T.D.5    Gartner, J.6
  • 40
    • 84886943299 scopus 로고    scopus 로고
    • In silico prediction of tumor antigens derived from functional missense mutations of the cancer gene census
    • Khalili JS, Hanson RW, Szallasi Z. In silico prediction of tumor antigens derived from functional missense mutations of the cancer gene census. Oncoimmunology. 2012;1(8):1281-9.
    • (2012) Oncoimmunology , vol.1 , Issue.8 , pp. 1281-1289
    • Khalili, J.S.1    Hanson, R.W.2    Szallasi, Z.3
  • 41
    • 78651330430 scopus 로고    scopus 로고
    • COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
    • Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, Beare D, et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res. 2011;39(Database issue):D945-50.
    • (2011) Nucleic Acids Res , vol.39 , Issue.DATABASE ISSUE
    • Forbes, S.A.1    Bindal, N.2    Bamford, S.3    Cole, C.4    Kok, C.Y.5    Beare, D.6
  • 42
    • 0030587077 scopus 로고    scopus 로고
    • Improved Induction of Melanoma-Reactive CTL with Peptides from the Melanoma Antigen gp100 Modified at HLA-A*0201-Binding Residues
    • Parkhurst MR, Salgaller ML, Southwood S, Robbins PF, Sette A, Rosenberg SA, et al. Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues. J Immunol. 1996;157(6):2539-48. (Pubitemid 126450467)
    • (1996) Journal of Immunology , vol.157 , Issue.6 , pp. 2539-2548
    • Parkhurst, M.R.1    Salgaller, M.L.2    Southwood, S.3    Robbins, P.F.4    Sette, A.5    Rosenberg, S.A.6    Kawakami, Y.7
  • 43
    • 0035879093 scopus 로고    scopus 로고
    • Identification of new epitopes from four different tumor-associated antigens: Recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity
    • Keogh E, Fikes J, Southwood S, Celis E, Chesnut R, Sette A. Identification of new epitopes from four different tumor-associated antigens: recognition of naturally processed epitopes correlates with HLA-A*0201- binding affinity. J Immunol. 2001;167(2):787-96. (Pubitemid 32660833)
    • (2001) Journal of Immunology , vol.167 , Issue.2 , pp. 787-796
    • Keogh, E.1    Fikes, J.2    Southwood, S.3    Celis, E.4    Chesnut, R.5    Sette, A.6
  • 44
    • 84876381248 scopus 로고    scopus 로고
    • Relapse or eradication of cancer is predicted by peptidemajor histocompatibility complex affinity
    • Engels B, Engelhard VH, Sidney J, Sette A, Binder DC, Liu RB, et al. Relapse or eradication of cancer is predicted by peptidemajor histocompatibility complex affinity. Cancer Cell. 2013;23(4):516-26.
    • (2013) Cancer Cell , vol.23 , Issue.4 , pp. 516-526
    • Engels, B.1    Engelhard, V.H.2    Sidney, J.3    Sette, A.4    Binder, D.C.5    Liu, R.B.6
  • 45
    • 84880276438 scopus 로고    scopus 로고
    • Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
    • Robbins PF, Lu YC, El-Gamil M, Li YF, Gross C, Gartner J, et al. Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells. Nat Med. 2013;19(6):747-52.
    • (2013) Nat Med , vol.19 , Issue.6 , pp. 747-752
    • Robbins, P.F.1    Lu, Y.C.2    El-Gamil, M.3    Li, Y.F.4    Gross, C.5    Gartner, J.6
  • 49
    • 84879101382 scopus 로고    scopus 로고
    • Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression
    • Lu YC, Yao X, Li YF, El-Gamil M, Dudley ME, Yang JC, et al. Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression. J Immunol. 2013;190(12):6034- 42.
    • (2013) J Immunol , vol.190 , Issue.12 , pp. 6034-6042
    • Lu, Y.C.1    Yao, X.2    Li, Y.F.3    El-Gamil, M.4    Dudley, M.E.5    Yang, J.C.6
  • 52
    • 67649616555 scopus 로고    scopus 로고
    • Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers
    • Hadrup SR, Bakker AH, Shu CJ, Andersen RS, van Veluw J, Hombrink P, et al. Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers. Nat Methods. 2009;6(7):520-6.
    • (2009) Nat Methods , vol.6 , Issue.7 , pp. 520-526
    • Hadrup, S.R.1    Bakker, A.H.2    Shu, C.J.3    Andersen, R.S.4    Van Veluw, J.5    Hombrink, P.6
  • 53
    • 67649610665 scopus 로고    scopus 로고
    • Simultaneous detection of many T-cell specificities using combinatorial tetramer staining
    • Newell EW, Klein LO, Yu W, Davis MM. Simultaneous detection of many T-cell specificities using combinatorial tetramer staining. Nat Methods. 2009;6(7):497-9.
    • (2009) Nat Methods , vol.6 , Issue.7 , pp. 497-499
    • Newell, E.W.1    Klein, L.O.2    Yu, W.3    Davis, M.M.4
  • 54
    • 84872841412 scopus 로고    scopus 로고
    • Tumor exome analysis reveals neoantigenspecific T-cell reactivity in an ipilimumab-responsive melanoma
    • van Rooij N, van Buuren MM, Philips D, Velds A, Toebes M, Heemskerk B, et al. Tumor exome analysis reveals neoantigenspecific T-cell reactivity in an ipilimumab-responsive melanoma. J Clin Oncol. 2013;31(32):e439-42.
    • (2013) J Clin Oncol , vol.31 , Issue.32
    • Van Rooij, N.1    Van Buuren, M.M.2    Philips, D.3    Velds, A.4    Toebes, M.5    Heemskerk, B.6
  • 55
    • 17844385106 scopus 로고    scopus 로고
    • The role of the proteasome in generating cytotoxic T-cell epitopes: Insights obtained from improved predictions of proteasomal cleavage
    • DOI 10.1007/s00251-005-0781-7
    • Nielsen M, Lundegaard C, Lund O, Keşmir C. The role of the proteasome in generating cytotoxic T-cell epitopes: insights obtained from improved predictions of proteasomal cleavage. Immunogenetics. 2005;57(1-2):33-41. (Pubitemid 40591245)
    • (2005) Immunogenetics , vol.57 , Issue.1-2 , pp. 33-41
    • Nielsen, M.1    Lundegaard, C.2    Lund, O.3    Kesmir, C.4
  • 56
    • 0032146234 scopus 로고    scopus 로고
    • HLA supertypes and supermotifs: A functional perspective on HLA polymorphism
    • DOI 10.1016/S0952-7915(98)80124-6
    • Sette A, Sidney J. HLA supertypes and supermotifs: a functional perspective on HLA polymorphism. Curr Opin Immunol. 1998;10(4):478-82. (Pubitemid 28393833)
    • (1998) Current Opinion in Immunology , vol.10 , Issue.4 , pp. 478-482
    • Sette, A.1    Sidney, J.2
  • 58
  • 59
    • 77953520516 scopus 로고    scopus 로고
    • MHC class II epitope predictive algorithms
    • Nielsen M, Lund O, Buus S, Lundegaard C. MHC class II epitope predictive algorithms. Immunology. 2010;130(3):319-28.
    • (2010) Immunology , vol.130 , Issue.3 , pp. 319-328
    • Nielsen, M.1    Lund, O.2    Buus, S.3    Lundegaard, C.4
  • 60
    • 84857822895 scopus 로고    scopus 로고
    • MHC class II tetramers
    • Nepom GT. MHC class II tetramers. J Immunol. 2012;188(6):2477-82.
    • (2012) J Immunol , vol.188 , Issue.6 , pp. 2477-2482
    • Nepom, G.T.1
  • 61
    • 38649128150 scopus 로고    scopus 로고
    • Class II major histocompatibility complex tetramer staining: Progress, problems, and prospects
    • DOI 10.1111/j.1365-2567.2007.02801.x
    • Vollers SS, Stern LJ. Class II major histocompatibility complex tetramer staining: progress, problems, and prospects. Immunology. 2008;123(3):305-13. (Pubitemid 351171199)
    • (2008) Immunology , vol.123 , Issue.3 , pp. 305-313
    • Vollers, S.S.1    Stern, L.J.2
  • 62
    • 41149130863 scopus 로고    scopus 로고
    • + T cells in anti-tumor immune responses
    • DOI 10.1111/j.1600-065X.2008.00616.x
    • Kennedy R, Celis E. Multiple roles for CD4+ T cells in antitumor immune responses. Immunol Rev. 2008;222:129-44. (Pubitemid 351430378)
    • (2008) Immunological Reviews , vol.222 , Issue.1 , pp. 129-144
    • Kennedy, R.1    Celis, E.2
  • 63
    • 0036852241 scopus 로고    scopus 로고
    • Cancer immunoediting: From immunosurveillance to tumor escape
    • DOI 10.1038/ni1102-991
    • Dunn GP, Bruce AT, Ikeda H, Old LJ, Schreiber RD. Cancer immunoediting: from immunosurveillance to tumor escape. Nat Immunol. 2002;3(11):991-8. (Pubitemid 35363648)
    • (2002) Nature Immunology , vol.3 , Issue.11 , pp. 991-998
    • Dunn, G.P.1    Bruce, A.T.2    Ikeda, H.3    Old, L.J.4    Schreiber, R.D.5
  • 64
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
    • Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science. 2011;331(6024):1565-70.
    • (2011) Science , vol.331 , Issue.6024 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 65
    • 84857118418 scopus 로고    scopus 로고
    • Expression of tumour-specific antigens underlies cancer immunoediting
    • DuPage M, Mazumdar C, Schmidt LM, Cheung AF, Jacks T. Expression of tumour-specific antigens underlies cancer immunoediting. Nature. 2012;482(7385):405-9.
    • (2012) Nature , vol.482 , Issue.7385 , pp. 405-409
    • DuPage, M.1    Mazumdar, C.2    Schmidt, L.M.3    Cheung, A.F.4    Jacks, T.5
  • 66
    • 84862776855 scopus 로고    scopus 로고
    • Cancer exome analysis reveals a T-celldependent mechanism of cancer immunoediting
    • Matsushita H, Vesely MD, Koboldt DC, Rickert CG, Uppaluri R, Magrini VJ, et al. Cancer exome analysis reveals a T-celldependent mechanism of cancer immunoediting. Nature. 2012; 482(7385):400-4.
    • (2012) Nature , vol.482 , Issue.7385 , pp. 400-404
    • Matsushita, H.1    Vesely, M.D.2    Koboldt, D.C.3    Rickert, C.G.4    Uppaluri, R.5    Magrini, V.J.6
  • 67
    • 70349969478 scopus 로고    scopus 로고
    • Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
    • Shah SP, Morin RD, Khattra J, Prentice L, Pugh T, Burleigh A, et al. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature. 2009;461(7265):809-13.
    • (2009) Nature , vol.461 , Issue.7265 , pp. 809-813
    • Shah, S.P.1    Morin, R.D.2    Khattra, J.3    Prentice, L.4    Pugh, T.5    Burleigh, A.6
  • 69
    • 84863393080 scopus 로고    scopus 로고
    • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
    • Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med. 2012;366(10):883-92.
    • (2012) N Engl J Med , vol.366 , Issue.10 , pp. 883-892
    • Gerlinger, M.1    Rowan, A.J.2    Horswell, S.3    Larkin, J.4    Endesfelder, D.5    Gronroos, E.6
  • 70
    • 84863230091 scopus 로고    scopus 로고
    • Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor
    • Xu X, Hou Y, Yin X, Bao L, Tang A, Song L, et al. Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor. Cell. 2012;148(5):886-95.
    • (2012) Cell , vol.148 , Issue.5 , pp. 886-895
    • Xu, X.1    Hou, Y.2    Yin, X.3    Bao, L.4    Tang, A.5    Song, L.6
  • 71
    • 78049398107 scopus 로고    scopus 로고
    • Distant metastasis occurs late during the genetic evolution of pancreatic cancer
    • Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature. 2010;467(7319):1114-7.
    • (2010) Nature , vol.467 , Issue.7319 , pp. 1114-1117
    • Yachida, S.1    Jones, S.2    Bozic, I.3    Antal, T.4    Leary, R.5    Fu, B.6
  • 75
    • 84867530182 scopus 로고    scopus 로고
    • Mutated BCR-ABL generates immunogenic T-cell epitopes in CML patients
    • Cai A, Keskin DB, DeLuca DS, Alonso A, Zhang W, Zhang GL, et al. Mutated BCR-ABL generates immunogenic T-cell epitopes in CML patients. Clin Cancer Res. 2012;18(20):5761-72.
    • (2012) Clin Cancer Res , vol.18 , Issue.20 , pp. 5761-5772
    • Cai, A.1    Keskin, D.B.2    DeLuca, D.S.3    Alonso, A.4    Zhang, W.5    Zhang, G.L.6
  • 76
    • 0028856743 scopus 로고
    • Vaccination with mutant ras peptides and induction of T-cell responsiveness in pancreatic carcinoma patients carrying the corresponding RAS mutation
    • Gjertsen MK, Bakka A, Breivik J, Saeterdal I, Solheim BG, Soreide O, et al. Vaccination with mutant ras peptides and induction of T-cell responsiveness in pancreatic carcinoma patients carrying the corresponding RAS mutation. Lancet. 1995;346(8987):1399-400.
    • (1995) Lancet , vol.346 , Issue.8987 , pp. 1399-1400
    • Gjertsen, M.K.1    Bakka, A.2    Breivik, J.3    Saeterdal, I.4    Solheim, B.G.5    Soreide, O.6
  • 79
    • 35449008469 scopus 로고    scopus 로고
    • Clinical evaluation of BCR-ABL peptide immunisation in chronic myeloid leukaemia: Results of the EPIC study
    • DOI 10.1038/sj.leu.2404858, PII 2404858
    • Rojas JM, Knight K, Wang L, Clark RE. Clinical evaluation of BCR-ABL peptide immunisation in chronic myeloid leukaemia: results of the EPIC study. Leukemia. 2007;21(11):2287-95. (Pubitemid 350011701)
    • (2007) Leukemia , vol.21 , Issue.11 , pp. 2287-2295
    • Rojas, J.M.1    Knight, K.2    Wang, L.3    Clark, R.E.4
  • 81
    • 76949105768 scopus 로고    scopus 로고
    • A census of predicted mutational epitopes suitable for immunologic cancer control
    • Warren RL, Holt RA. A census of predicted mutational epitopes suitable for immunologic cancer control. Hum Immunol. 2010;71(3):245-54.
    • (2010) Hum Immunol , vol.71 , Issue.3 , pp. 245-254
    • Warren, R.L.1    Holt, R.A.2
  • 82
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosurveillance: Immunoselection and immunosubversion
    • DOI 10.1038/nri1936, PII NRI1936
    • Zitvogel L, Tesniere A, Kroemer G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol. 2006;6(10):715-27. (Pubitemid 44453458)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.10 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3
  • 83
    • 70350458112 scopus 로고    scopus 로고
    • Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity
    • Hinrichs CS, Borman ZA, Cassard L, Gattinoni L, Spolski R, Yu Z, et al. Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity. Proc Natl Acad Sci USA. 2009;106(41):17469-74.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.41 , pp. 17469-17474
    • Hinrichs, C.S.1    Borman, Z.A.2    Cassard, L.3    Gattinoni, L.4    Spolski, R.5    Yu, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.