Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses

Cell

Volumn 169, Issue 4, 2017, Pages 750-765.e17

  Lavin, Yonit ^a   Kobayashi, Soma ^a   Leader, Andrew ^a   Amir, El ad David ^a   Elefant, Naama ^b   Bigenwald, Camille ^a   Remark, Romain ^a,e   Sweeney, Robert ^a   Becker, Christian D ^a   Levine, Jacob H ^c   Meinhof, Klaus ^a   Chow, Andrew ^a   Kim Shulze, Seunghee ^a   Wolf, Andrea ^a   Medaglia, Chiara ^b   Li, Hanjie ^b   Rytlewski, Julie A ^d   Emerson, Ryan O ^d   Solovyov, Alexander ^a   Greenbaum, Benjamin D ^a   Sanders, Catherine ^d   Vignali, Marissa ^d   Beasley, Mary Beth ^a   Flores, Raja ^a   Gnjatic, Sacha ^a   Pe'er, Dana ^c   Rahman, Adeeb ^a   Amit, Ido ^b   Merad, Miriam ^a   more..

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d ADAPTIVE BIOTECHNOLOGIES   (United States)

^e INNATE PHARMA   (France)

Author keywords

CD141+ DC; CD1c+ DC; human non small cell lung cancer (NSCLC); immune cell atlas; lung adenocarcinoma; NK Cell; T Cell; TIM; TLS; tumor macrophage

Indexed keywords

41BB ANTIGEN; APOLIPOPROTEIN E; CD14 ANTIGEN; CD141 PROTEIN; CD1C ANTIGEN; CD38 ANTIGEN; CD39 ANTIGEN; CD64 ANTIGEN; CHEMOKINE RECEPTOR CCR4; CSF1 R PROTEIN; CSF2 R PROTEIN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; GLYCOPROTEIN P 15095; GRANZYME B; HLA DR ANTIGEN; ICOS PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; PD 1 ANTIGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN; TETRASPANIN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BONE MARROW CELL; CANCER STAGING; CD8+ T LYMPHOCYTE; CELL COMPOSITION; CELL ISOLATION; CELLULAR IMMUNITY; CLINICAL ARTICLE; COHORT ANALYSIS; COMPARATIVE STUDY; CYTOKINE PRODUCTION; FEMALE; FLOW CYTOMETRY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INNATE IMMUNITY; LUNG ADENOCARCINOMA; LYMPHOCYTIC INFILTRATION; MALE; MONONUCLEAR PHAGOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SINGLE CELL ANALYSIS; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TRANSCRIPTOMICS; TUMOR MICROENVIRONMENT; ADENOCARCINOMA; DENDRITIC CELL; IMMUNOLOGY; LUNG TUMOR; MACROPHAGE; NATURAL KILLER CELL; PATHOLOGY; PROCEDURES; T LYMPHOCYTE;

ADENOCARCINOMA; DENDRITIC CELLS; HUMANS; IMMUNITY, INNATE; KILLER CELLS, NATURAL; LUNG NEOPLASMS; MACROPHAGES; SINGLE-CELL ANALYSIS; T-LYMPHOCYTES; TUMOR MICROENVIRONMENT;

EID: 85018766073     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.04.014     Document Type: Article

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