-
1
-
-
77954899030
-
Phase i study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer JR, Drake CG,Wollner I, et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010;28(19): 3167-3175.
-
(2010)
J Clin Oncol
, vol.28
, Issue.19
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
-
2
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366(26): 2443-2454.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
3
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid O, Robert C, Daud A, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med. 2013;369(2):134-144.
-
(2013)
N Engl J Med
, vol.369
, Issue.2
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
-
4
-
-
84898973055
-
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
-
Topalian SL, Sznol M, McDermott DF, et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol. 2014;32(10): 1020-1030.
-
(2014)
J Clin Oncol
, vol.32
, Issue.10
, pp. 1020-1030
-
-
Topalian, S.L.1
Sznol, M.2
McDermott, D.F.3
-
5
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, Kluger H, Callahan MK, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med. 2013;369(2):122-133.
-
(2013)
N Engl J Med
, vol.369
, Issue.2
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
-
6
-
-
84936147067
-
Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
-
Larkin J, Chiarion-Sileni V, Gonzalez R, et al. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med. 2015;373(1):23-34.
-
(2015)
N Engl J Med
, vol.373
, Issue.1
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
-
7
-
-
84953309212
-
Immune-related adverse events with immune checkpoint blockade: A comprehensive review
-
Michot JM, Bigenwald C, Champiat S, et al. Immune-related adverse events with immune checkpoint blockade: a comprehensive review. Eur J Cancer. 2016;54:139-148.
-
(2016)
Eur J Cancer
, vol.54
, pp. 139-148
-
-
Michot, J.M.1
Bigenwald, C.2
Champiat, S.3
-
8
-
-
84930181050
-
Cancer immunotherapy and immune-related response assessment: The role of radiologists in the new arena of cancer treatment
-
Nishino M, Tirumani SH, Ramaiya NH, Hodi FS. Cancer immunotherapy and immune-related response assessment: the role of radiologists in the new arena of cancer treatment. Eur J Radiol. 2015; 84(7):1259-1268.
-
(2015)
Eur J Radiol
, vol.84
, Issue.7
, pp. 1259-1268
-
-
Nishino, M.1
Tirumani, S.H.2
Ramaiya, N.H.3
Hodi, F.S.4
-
9
-
-
84962476269
-
Radiographic profiling of immune-related adverse events in advanced melanoma patients treated with ipilimumab
-
Tirumani SH, Ramaiya NH, Keraliya A, et al. Radiographic profiling of immune-related adverse events in advanced melanoma patients treated with ipilimumab. Cancer Immunol Res. 2015;3(10): 1185-1192.
-
(2015)
Cancer Immunol Res
, vol.3
, Issue.10
, pp. 1185-1192
-
-
Tirumani, S.H.1
Ramaiya, N.H.2
Keraliya, A.3
-
10
-
-
84864052441
-
Management of immune-related adverse events and kinetics of response with ipilimumab
-
Weber JS, Kahler KC, Hauschild A. Management of immune-related adverse events and kinetics of response with ipilimumab. J Clin Oncol. 2012;30 (21):2691-2697.
-
(2012)
J Clin Oncol
, vol.30
, Issue.21
, pp. 2691-2697
-
-
Weber, J.S.1
Kahler, K.C.2
Hauschild, A.3
-
11
-
-
84936749833
-
Overall survival and long-term safety of nivolumab (anti-programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non-small-cell lung cancer
-
Gettinger SN, Horn L, Gandhi L, et al. Overall survival and long-term safety of nivolumab (anti-programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non-small-cell lung cancer. J Clin Oncol. 2015;33(18):2004-2012.
-
(2015)
J Clin Oncol
, vol.33
, Issue.18
, pp. 2004-2012
-
-
Gettinger, S.N.1
Horn, L.2
Gandhi, L.3
-
12
-
-
84929481480
-
Pembrolizumab for the treatment of non-small-cell lung cancer
-
KEYNOTE-001 Investigators
-
Garon EB, Rizvi NA, Hui R, et al.; KEYNOTE-001 Investigators. Pembrolizumab for the treatment of non-small-cell lung cancer. N Engl J Med. 2015;372 (21):2018-2028.
-
(2015)
N Engl J Med
, vol.372
, Issue.21
, pp. 2018-2028
-
-
Garon, E.B.1
Rizvi, N.A.2
Hui, R.3
-
13
-
-
84937053577
-
Anti-PD-1-related pneumonitis during cancer immunotherapy
-
Nishino M, Sholl LM, Hodi FS, Hatabu H, Ramaiya NH. Anti-PD-1-related pneumonitis during cancer immunotherapy. N Engl J Med. 2015;373(3): 288-290.
-
(2015)
N Engl J Med
, vol.373
, Issue.3
, pp. 288-290
-
-
Nishino, M.1
Sholl, L.M.2
Hodi, F.S.3
Hatabu, H.4
Ramaiya, N.H.5
-
14
-
-
0000642942
-
Some methods for strengthening the common Χ2 tests
-
CochranWG. Some methods for strengthening the common Χ2 tests. Biometrics. 1954;10:417-451.
-
(1954)
Biometrics
, vol.10
, pp. 417-451
-
-
Cochran, W.G.1
-
15
-
-
0041876133
-
Measuring inconsistency inmeta-analyses
-
Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency inmeta-analyses. BMJ. 2003;327(7414):557-560.
-
(2003)
BMJ
, vol.327
, Issue.7414
, pp. 557-560
-
-
Higgins, J.P.1
Thompson, S.G.2
Deeks, J.J.3
Altman, D.G.4
-
16
-
-
0022992740
-
Meta-analysis in clinical trials
-
DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7(3):177-188.
-
(1986)
Control Clin Trials
, vol.7
, Issue.3
, pp. 177-188
-
-
DerSimonian, R.1
Laird, N.2
-
17
-
-
0028659004
-
Operating characteristics of a rank correlation test for publication bias
-
Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50(4):1088-1101.
-
(1994)
Biometrics
, vol.50
, Issue.4
, pp. 1088-1101
-
-
Begg, C.B.1
Mazumdar, M.2
-
18
-
-
0030922816
-
Bias in meta-analysis detected by a simple, graphical test
-
Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629-634.
-
(1997)
BMJ
, vol.315
, Issue.7109
, pp. 629-634
-
-
Egger, M.1
Davey Smith, G.2
Schneider, M.3
Minder, C.4
-
19
-
-
84931083080
-
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): A randomised, controlled, open-label, phase 3 trial
-
Weber JS, D'Angelo SP, Minor D, et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial. Lancet Oncol. 2015;16(4):375-384.
-
(2015)
Lancet Oncol
, vol.16
, Issue.4
, pp. 375-384
-
-
Weber, J.S.1
D'Angelo, S.P.2
Minor, D.3
-
20
-
-
84925222119
-
Nivolumab in previously untreated melanoma without BRAF mutation
-
Robert C, Long GV, Brady B, et al. Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med. 2015;372(4):320-330.
-
(2015)
N Engl J Med
, vol.372
, Issue.4
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
-
21
-
-
84924901863
-
Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): A phase 2, single-arm trial
-
Rizvi NA, Mazieres J, Planchard D, et al. Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial. Lancet Oncol. 2015;16(3):257-265.
-
(2015)
Lancet Oncol
, vol.16
, Issue.3
, pp. 257-265
-
-
Rizvi, N.A.1
Mazieres, J.2
Planchard, D.3
-
22
-
-
84929572937
-
Nivolumab formetastatic renal cell carcinoma: Results of a randomized phase II trial
-
Motzer RJ, Rini BI, McDermott DF, et al. Nivolumab formetastatic renal cell carcinoma: results of a randomized phase II trial. J Clin Oncol. 2015;33(13):1430-1437.
-
(2015)
J Clin Oncol
, vol.33
, Issue.13
, pp. 1430-1437
-
-
Motzer, R.J.1
Rini, B.I.2
McDermott, D.F.3
-
23
-
-
84929361060
-
Survival, durable response, and long-term safety in patients with previously treated advanced renal cell carcinoma receiving nivolumab
-
McDermott DF, Drake CG, Sznol M, et al. Survival, durable response, and long-term safety in patients with previously treated advanced renal cell carcinoma receiving nivolumab. J Clin Oncol. 2015; 33(18):2013-2020.
-
(2015)
J Clin Oncol
, vol.33
, Issue.18
, pp. 2013-2020
-
-
McDermott, D.F.1
Drake, C.G.2
Sznol, M.3
-
24
-
-
84908354848
-
Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial
-
Robert C, Ribas A,Wolchok JD, et al. Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet. 2014;384(9948):1109-1117.
-
(2014)
Lancet
, vol.384
, Issue.9948
, pp. 1109-1117
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
-
25
-
-
84880511594
-
Development of ipilimumab: A novel immunotherapeutic approach for the treatment of advanced melanoma
-
Wolchok JD, Hodi FS,Weber JS, et al. Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma. Ann N Y Acad Sci. 2013;1291:1-13
-
(2013)
Ann N y Acad Sci
, vol.1291
, pp. 1-13
-
-
Wolchok, J.D.1
Hodi, F.S.2
Weber, J.S.3
-
26
-
-
84938205998
-
Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): A randomised, controlled, phase 2 trial
-
Ribas A, Puzanov I, Dummer R, et al. Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial. Lancet Oncol. 2015;16(8):908-918.
-
(2015)
Lancet Oncol
, vol.16
, Issue.8
, pp. 908-918
-
-
Ribas, A.1
Puzanov, I.2
Dummer, R.3
-
27
-
-
84945554100
-
Phase i study of pembrolizumab (MK-3475; Anti-PD-1 monoclonal antibody) in patients with advanced solid tumors
-
Patnaik A, Kang SP, Rasco D, et al. Phase I study of pembrolizumab (MK-3475; anti-PD-1 monoclonal antibody) in patients with advanced solid tumors. Clin Cancer Res. 2015;21(19):4286-4293.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.19
, pp. 4286-4293
-
-
Patnaik, A.1
Kang, S.P.2
Rasco, D.3
-
28
-
-
84932628341
-
PD-1 blockade in tumors with mismatch-repair deficiency
-
Le DT, Uram JN,Wang H, et al. PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med. 2015;372(26):2509-2520.
-
(2015)
N Engl J Med
, vol.372
, Issue.26
, pp. 2509-2520
-
-
Le, D.T.1
Uram, J.N.2
Wang, H.3
-
29
-
-
84951126341
-
Safety and antitumor activity of anti-PD-1 antibody, nivolumab, in patients with platinum-resistant ovarian cancer
-
Hamanishi J, Mandai M, Ikeda T, et al. Safety and antitumor activity of anti-PD-1 antibody, nivolumab, in patients with platinum-resistant ovarian cancer. J Clin Oncol. 2015;33(34):4015-4022.
-
(2015)
J Clin Oncol
, vol.33
, Issue.34
, pp. 4015-4022
-
-
Hamanishi, J.1
Mandai, M.2
Ikeda, T.3
-
30
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
-
Brahmer J, Reckamp KL, Baas P, et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med. 2015;373(2):123-135.
-
(2015)
N Engl J Med
, vol.373
, Issue.2
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
-
31
-
-
84944937210
-
Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
-
Borghaei H, Paz-Ares L, Horn L, et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N Engl J Med. 2015;373 (17):1627-1639.
-
(2015)
N Engl J Med
, vol.373
, Issue.17
, pp. 1627-1639
-
-
Borghaei, H.1
Paz-Ares, L.2
Horn, L.3
-
32
-
-
84923166043
-
Safety, correlative markers, and clinical results of adjuvant nivolumab in combination with vaccine in resected high-risk metastatic melanoma
-
Gibney GT, Kudchadkar RR, DeConti RC, et al. Safety, correlative markers, and clinical results of adjuvant nivolumab in combination with vaccine in resected high-risk metastatic melanoma. Clin Cancer Res. 2015;21(4):712-720.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.4
, pp. 712-720
-
-
Gibney, G.T.1
Kudchadkar, R.R.2
DeConti, R.C.3
-
33
-
-
84929481482
-
Nivolumab and ipilimumab versus ipilimumab in untreated melanoma
-
PostowMA, Chesney J, Pavlick AC, et al. Nivolumab and ipilimumab versus ipilimumab in untreated melanoma. N Engl J Med. 2015;372(21): 2006-2017.
-
(2015)
N Engl J Med
, vol.372
, Issue.21
, pp. 2006-2017
-
-
Postow, M.A.1
Chesney, J.2
Pavlick, A.C.3
-
34
-
-
84929481481
-
Pembrolizumab versus ipilimumab in advanced melanoma
-
KEYNOTE-006 investigators
-
Robert C, Schachter J, Long GV, et al.; KEYNOTE-006 investigators. Pembrolizumab versus ipilimumab in advanced melanoma. N Engl J Med. 2015;372(26):2521-2532.
-
(2015)
N Engl J Med
, vol.372
, Issue.26
, pp. 2521-2532
-
-
Robert, C.1
Schachter, J.2
Long, G.V.3
-
35
-
-
84925221855
-
PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma
-
Ansell SM, Lesokhin AM, Borrello I, et al. PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma. N Engl J Med. 2015;372(4): 311-319.
-
(2015)
N Engl J Med
, vol.372
, Issue.4
, pp. 311-319
-
-
Ansell, S.M.1
Lesokhin, A.M.2
Borrello, I.3
-
36
-
-
84946607195
-
Nivolumab versus everolimus in advanced renal-cell carcinoma
-
CheckMate 025 Investigators
-
Motzer RJ, Escudier B, McDermott DF, et al.; CheckMate 025 Investigators. Nivolumab versus everolimus in advanced renal-cell carcinoma. N Engl J Med. 2015;373(19):1803-1813.
-
(2015)
N Engl J Med
, vol.373
, Issue.19
, pp. 1803-1813
-
-
Motzer, R.J.1
Escudier, B.2
McDermott, D.F.3
-
37
-
-
84892866206
-
Safety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or-naive melanoma
-
Weber JS, Kudchadkar RR, Yu B, et al. Safety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or-naive melanoma. J Clin Oncol. 2013;31(34):4311-4318.
-
(2013)
J Clin Oncol
, vol.31
, Issue.34
, pp. 4311-4318
-
-
Weber, J.S.1
Kudchadkar, R.R.2
Yu, B.3
-
38
-
-
10444256482
-
The impact of smoking status on the behavior and survival outcome of patients with advanced non-small cell lung cancer: A retrospective analysis
-
Toh CK,Wong EH, LimWT, et al. The impact of smoking status on the behavior and survival outcome of patients with advanced non-small cell lung cancer: a retrospective analysis. Chest. 2004; 126(6):1750-1756.
-
(2004)
Chest
, vol.126
, Issue.6
, pp. 1750-1756
-
-
Toh, C.K.1
Wong, E.H.2
Lim, W.T.3
-
39
-
-
0036209103
-
Association of malignancy with diseases causing interstitial pulmonary changes
-
Bouros D, Hatzakis K, Labrakis H, Zeibecoglou K. Association of malignancy with diseases causing interstitial pulmonary changes. Chest. 2002;121(4): 1278-1289.
-
(2002)
Chest
, vol.121
, Issue.4
, pp. 1278-1289
-
-
Bouros, D.1
Hatzakis, K.2
Labrakis, H.3
Zeibecoglou, K.4
-
40
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM,Werb Z. Inflammation and cancer. Nature. 2002;420(6917):860-867.
-
(2002)
Nature
, vol.420
, Issue.6917
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
41
-
-
84944261579
-
Immune-related adverse events, need for systemic immunosuppression, and effects on survival and time to treatment failure in patients with melanoma treated with ipilimumab at Memorial Sloan Kettering Cancer Center
-
Horvat TZ, Adel NG, Dang TO, et al. Immune-related adverse events, need for systemic immunosuppression, and effects on survival and time to treatment failure in patients with melanoma treated with ipilimumab at Memorial Sloan Kettering Cancer Center. J Clin Oncol. 2015;33(28): 3193-3198.
-
(2015)
J Clin Oncol
, vol.33
, Issue.28
, pp. 3193-3198
-
-
Horvat, T.Z.1
Adel, N.G.2
Dang, T.O.3
-
42
-
-
84908664534
-
Ipilimumab plus sargramostim vs ipilimumab alone for treatment of metastatic melanoma: A randomized clinical trial
-
Hodi FS, Lee S, McDermott DF, et al. Ipilimumab plus sargramostim vs ipilimumab alone for treatment of metastatic melanoma: a randomized clinical trial. JAMA. 2014;312(17): 1744-1753.
-
(2014)
JAMA
, vol.312
, Issue.17
, pp. 1744-1753
-
-
Hodi, F.S.1
Lee, S.2
McDermott, D.F.3
-
43
-
-
84962038946
-
Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): A multicentre, open-label, phase 2 randomised controlled trial
-
10030 POPLAR Study Group
-
Fehrenbacher L, Spira A, Ballinger M, et al.; POPLAR Study Group. Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial. Lancet. 2016;387(10030):1837-1846.
-
(2016)
Lancet
, vol.387
, pp. 1837-1846
-
-
Fehrenbacher, L.1
Spira, A.2
Ballinger, M.3
-
44
-
-
84962497081
-
Atezolizumab, an anti-programmed death-ligand 1 antibody, inmetastatic renal cell carcinoma: Long-term safety, clinical activity, and immune correlates from a phase Ia study
-
McDermott DF, Sosman JA, Sznol M, et al. Atezolizumab, an anti-programmed death-ligand 1 antibody, inmetastatic renal cell carcinoma: long-term safety, clinical activity, and immune correlates from a phase Ia study. J Clin Oncol. 2016; 34(8):833-842.
-
(2016)
J Clin Oncol
, vol.34
, Issue.8
, pp. 833-842
-
-
McDermott, D.F.1
Sosman, J.A.2
Sznol, M.3
-
45
-
-
84959577118
-
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: A single-arm, multicentre, phase 2 trial
-
Rosenberg JE, Hoffman-Censits J, Powles T, et al. Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial. Lancet. 2016;387(10031): 1909-1920.
-
(2016)
Lancet
, vol.387
, pp. 1909-1920
-
-
Rosenberg, J.E.1
Hoffman-Censits, J.2
Powles, T.3
|