A high density of tertiary lymphoid structure B cells in lung tumors is associated with increased CD4+ T cell receptor repertoire clonality

OncoImmunology

Volumn 4, Issue 12, 2015, Pages

  Zhu, Wei ^a   Germain, Claire ^b,c,d   Liu, Zheng ^a   Sebastian, Yinong ^a   Devi, Priyanka ^b,c,d   Knockaert, Samantha ^b,c,d   Brohawn, Philip ^a   Lehmann, Kim ^a   Damotte, Diane ^b,c,d,e   Validire, Pierre ^b,c,d,f   Yao, Yihong ^a   Valge Archer, Viia ^g   Hammond, Scott A ^a   Dieu Nosjean, Marie Caroline ^b,c,d   Higgs, Brandon W ^a  

^a MEDIMMUNE   (United States)

^b CENTRE DE RECHERCHE DES CORDELIERS   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d Assistance Publique Hôpitaux de Paris   (France)

^e Institut Mutualiste Montsouris ^*  (France)

^f INSTITUT MUTUALISTE MONTSOURIS   (France)

^g MEDIMMUNE LTD   (United Kingdom)

Author keywords

deep sequencing; non small cell lung cancer; TCR BCR repertoire; tertiary lymphoid structure

Indexed keywords

B LYMPHOCYTE RECEPTOR; IMMUNOGLOBULIN HEAVY CHAIN; T LYMPHOCYTE RECEPTOR;

ADENOCARCINOMA; ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL EXPANSION; CELL SELECTION; CLINICAL ARTICLE; COMPLEMENTARITY DETERMINING REGION; FEMALE; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LARGE CELL CARCINOMA; MALE; MEMORY T LYMPHOCYTE; NEXT GENERATION SEQUENCING; NON SMALL CELL LUNG CANCER; OVERALL SURVIVAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SQUAMOUS CELL CARCINOMA;

EID: 84944548558     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2015.1051922     Document Type: Article

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