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Volumn 6, Issue 1, 2016, Pages 71-79

Cancer immunotherapy with immunomodulatory anti-CD137 and anti–PD-1 monoclonal antibodies requires BATF3-dependent dendritic cells

Author keywords

[No Author keywords available]

Indexed keywords

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CD137 ANTIGEN; MONOCLONAL ANTIBODY; PF 05082566; PROGRAMMED DEATH 1 LIGAND 1; UNCLASSIFIED DRUG; URELUMAB; PDCD1 PROTEIN, HUMAN; PROGRAMMED DEATH 1 RECEPTOR; REPRESSOR PROTEIN; SNFT PROTEIN, MOUSE;

EID: 84954053287     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-15-0510     Document Type: Article
Times cited : (360)

References (29)
  • 1
    • 84928770388 scopus 로고    scopus 로고
    • Neoantigens in cancer immunotherapy
    • Schumacher TN, Schreiber RD. Neoantigens in cancer immunotherapy. Science 2015; 348: 69-74.
    • (2015) Science , vol.348 , pp. 69-74
    • Schumacher, T.N.1    Schreiber, R.D.2
  • 4
    • 0038326676 scopus 로고    scopus 로고
    • Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells
    • Nowak AK, Lake RA, Marzo AL, Scott B, Heath WR, Collins EJ, et al. Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells. J Immunol 2003; 170: 4905-13.
    • (2003) J Immunol , vol.170 , pp. 4905-4913
    • Nowak, A.K.1    Lake, R.A.2    Marzo, A.L.3    Scott, B.4    Heath, W.R.5    Collins, E.J.6
  • 6
    • 56449097442 scopus 로고    scopus 로고
    • Batf3 deficiency reveals a critical role for CD8alphaD dendritic cells in cytotoxic T cell immunity
    • Hildner K, Edelson BT, Purtha WE, Diamond M, Matsushita H, Kohyama M, et al. Batf3 deficiency reveals a critical role for CD8alphaD dendritic cells in cytotoxic T cell immunity. Science 2008; 322: 1097-100.
    • (2008) Science , vol.322 , pp. 1097-1100
    • Hildner, K.1    Edelson, B.T.2    Purtha, W.E.3    Diamond, M.4    Matsushita, H.5    Kohyama, M.6
  • 7
    • 84876469090 scopus 로고    scopus 로고
    • CD8alphaeeDCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3
    • Seillet C, Jackson JT, Markey KA, Brady HJ, Hill GR, Macdonald KP, et al. CD8alphaeeDCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3. Blood 2013; 121: 1574-83.
    • (2013) Blood , vol.121 , pp. 1574-1583
    • Seillet, C.1    Jackson, J.T.2    Markey, K.A.3    Brady, H.J.4    Hill, G.R.5    Macdonald, K.P.6
  • 8
    • 84921065511 scopus 로고    scopus 로고
    • Batf3-dependent CD103dddendritic cells are major producers of IL-12 that drive local Th1 immunity against Leishmania major infection in mice
    • Martinez-Lopez M, Iborra S, Conde-Garrosa R, Sancho D. Batf3-dependent CD103dddendritic cells are major producers of IL-12 that drive local Th1 immunity against Leishmania major infection in mice. Eur J Immunol 2015; 45: 119-29.
    • (2015) Eur J Immunol , vol.45 , pp. 119-129
    • Martinez-Lopez, M.1    Iborra, S.2    Conde-Garrosa, R.3    Sancho, D.4
  • 9
    • 84936953099 scopus 로고    scopus 로고
    • Melanoma-intrinsic beta-catenin signalling prevents anti-tumour immunity
    • Spranger S, Bao R, Gajewski TF. Melanoma-intrinsic beta-catenin signalling prevents anti-tumour immunity. Nature 2015; 523: 231-5.
    • (2015) Nature , vol.523 , pp. 231-235
    • Spranger, S.1    Bao, R.2    Gajewski, T.F.3
  • 10
    • 84876753532 scopus 로고    scopus 로고
    • Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells
    • Ma Y, Adjemian S, Mattarollo SR, Yamazaki T, Aymeric L, Yang H, et al. Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells. Immunity 2013; 38: 729-41.
    • (2013) Immunity , vol.38 , pp. 729-741
    • Ma, Y.1    Adjemian, S.2    Mattarollo, S.R.3    Yamazaki, T.4    Aymeric, L.5    Yang, H.6
  • 11
  • 12
    • 84919468025 scopus 로고    scopus 로고
    • Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity
    • Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, et al. Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity. Cancer Cell 2014; 26: 638-52.
    • (2014) Cancer Cell , vol.26 , pp. 638-652
    • Broz, M.L.1    Binnewies, M.2    Boldajipour, B.3    Nelson, A.E.4    Pollack, J.L.5    Erle, D.J.6
  • 13
    • 84912089439 scopus 로고    scopus 로고
    • Macrophage IL-10 blocks CD8NNT cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells
    • Ruffell B, Chang-Strachan D, Chan V, Rosenbusch A, Ho CM, Pryer N, et al. Macrophage IL-10 blocks CD8NNT cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells. Cancer Cell 2014; 26: 623-37.
    • (2014) Cancer Cell , vol.26 , pp. 623-637
    • Ruffell, B.1    Chang-Strachan, D.2    Chan, V.3    Rosenbusch, A.4    Ho, C.M.5    Pryer, N.6
  • 14
    • 77953484184 scopus 로고    scopus 로고
    • Characterization of human DNGR-1JJBDCA3BBleukocytes as putative equivalents of mouse CD8alphappdendritic cells
    • Poulin LF, Salio M, Griessinger E, Anjos-Afonso F, Craciun L, Chen JL, et al. Characterization of human DNGR-1JJBDCA3BBleukocytes as putative equivalents of mouse CD8alphappdendritic cells. J Exp Med 2010; 207: 1261-71.
    • (2010) J Exp Med , vol.207 , pp. 1261-1271
    • Poulin, L.F.1    Salio, M.2    Griessinger, E.3    Anjos-Afonso, F.4    Craciun, L.5    Chen, J.L.6
  • 15
    • 84874889330 scopus 로고    scopus 로고
    • Clinical development of immunostimulatory monoclonal antibodies and opportunities for combination
    • Melero I, Grimaldi AM, Perez-Gracia JL, Ascierto PA. Clinical development of immunostimulatory monoclonal antibodies and opportunities for combination. Clin Cancer Res 2013; 19: 997-1008.
    • (2013) Clin Cancer Res , vol.19 , pp. 997-1008
    • Melero, I.1    Grimaldi, A.M.2    Perez-Gracia, J.L.3    Ascierto, P.A.4
  • 17
    • 84923335913 scopus 로고    scopus 로고
    • Cancer: Antitumour immunity gets a boost
    • Wolchok JD, Chan TA. Cancer: Antitumour immunity gets a boost. Nature 2014; 515: 496-8.
    • (2014) Nature , vol.515 , pp. 496-498
    • Wolchok, J.D.1    Chan, T.A.2
  • 19
    • 0031007143 scopus 로고    scopus 로고
    • Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
    • Melero I, Shuford WW, Newby SA, Aruffo A, Ledbetter JA, Hellstrom KE, et al. Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nat Med 1997; 3: 682-5.
    • (1997) Nat Med , vol.3 , pp. 682-685
    • Melero, I.1    Shuford, W.W.2    Newby, S.A.3    Aruffo, A.4    Ledbetter, J.A.5    Hellstrom, K.E.6
  • 21
    • 84866335513 scopus 로고    scopus 로고
    • The HIF-1alpha hypoxia response in tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy
    • Palazon A, Martinez-Forero I, Teijeira A, Morales-Kastresana A, Alfaro C, Sanmamed MF, et al. The HIF-1alpha hypoxia response in tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy. Cancer Discov 2012; 2: 608-23.
    • (2012) Cancer Discov , vol.2 , pp. 608-623
    • Palazon, A.1    Martinez-Forero, I.2    Teijeira, A.3    Morales-Kastresana, A.4    Alfaro, C.5    Sanmamed, M.F.6
  • 22
    • 84886427186 scopus 로고    scopus 로고
    • Controlled local delivery of CTLA-4 blocking antibody induces CD8l T-cell-dependent tumor eradication and decreases risk of toxic side effects
    • Fransen MF, van der Sluis TC, Ossendorp F, Arens R, Melief CJ. Controlled local delivery of CTLA-4 blocking antibody induces CD8l T-cell-dependent tumor eradication and decreases risk of toxic side effects. Clin Cancer Res 2013; 19: 5381-9.
    • (2013) Clin Cancer Res , vol.19 , pp. 5381-5389
    • Fransen, M.F.1    van der Sluis, T.C.2    Ossendorp, F.3    Arens, R.4    Melief, C.J.5
  • 23
    • 0034100678 scopus 로고    scopus 로고
    • The envelope protein of an endogenous murine retrovirus is a tumor-associated T-cell antigen for multiple murine tumors
    • Yang JC, Perry-Lalley D. The envelope protein of an endogenous murine retrovirus is a tumor-associated T-cell antigen for multiple murine tumors. J Immunother 2000; 23: 177-83.
    • (2000) J Immunother , vol.23 , pp. 177-183
    • Yang, J.C.1    Perry-Lalley, D.2
  • 24
    • 84920956731 scopus 로고    scopus 로고
    • Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
    • Yadav M, Jhunjhunwala S, Phung QT, Lupardus P, Tanguay J, Bumbaca S, et al. Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature 2014; 515: 572-6.
    • (2014) Nature , vol.515 , pp. 572-576
    • Yadav, M.1    Jhunjhunwala, S.2    Phung, Q.T.3    Lupardus, P.4    Tanguay, J.5    Bumbaca, S.6
  • 25
    • 70349243743 scopus 로고    scopus 로고
    • In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb
    • Murillo O, Dubrot J, Palazon A, Arina A, Azpilikueta A, Alfaro C, et al. In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb. Eur J Immunol 2009; 39: 2424-36.
    • (2009) Eur J Immunol , vol.39 , pp. 2424-2436
    • Murillo, O.1    Dubrot, J.2    Palazon, A.3    Arina, A.4    Azpilikueta, A.5    Alfaro, C.6
  • 26
    • 70350234739 scopus 로고    scopus 로고
    • Tumor vaccines expressing flt3 ligand synergize with ctla-4 blockade to reject preimplanted tumors
    • Curran MA, Allison JP. Tumor vaccines expressing flt3 ligand synergize with ctla-4 blockade to reject preimplanted tumors. Cancer Res 2009; 69: 7747-55.
    • (2009) Cancer Res , vol.69 , pp. 7747-7755
    • Curran, M.A.1    Allison, J.P.2
  • 27
    • 80355136945 scopus 로고    scopus 로고
    • Host type I IFN signals are required for antitumor CD8HHT cell responses through CD8{alpha}ttdendritic cells
    • Fuertes MB, Kacha AK, Kline J, Woo SR, Kranz DM, Murphy KM, et al. Host type I IFN signals are required for antitumor CD8HHT cell responses through CD8{alpha}ttdendritic cells. J Exp Med 2011; 208: 2005-16.
    • (2011) J Exp Med , vol.208 , pp. 2005-2016
    • Fuertes, M.B.1    Kacha, A.K.2    Kline, J.3    Woo, S.R.4    Kranz, D.M.5    Murphy, K.M.6
  • 28
    • 84920921528 scopus 로고    scopus 로고
    • Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
    • Gubin MM, Zhang X, Schuster H, Caron E, Ward JP, Noguchi T, et al. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature 2014; 515: 577-81.
    • (2014) Nature , vol.515 , pp. 577-581
    • Gubin, M.M.1    Zhang, X.2    Schuster, H.3    Caron, E.4    Ward, J.P.5    Noguchi, T.6
  • 29
    • 84911932242 scopus 로고    scopus 로고
    • Selective and efficient generation of functional Batf3-dependent CD103dddendritic cells from mouse bone marrow
    • Mayer CT, Ghorbani P, Nandan A, Dudek M, Arnold-Schrauf C, Hesse C, et al. Selective and efficient generation of functional Batf3-dependent CD103dddendritic cells from mouse bone marrow. Blood 2014; 124: 3081-91.
    • (2014) Blood , vol.124 , pp. 3081-3091
    • Mayer, C.T.1    Ghorbani, P.2    Nandan, A.3    Dudek, M.4    Arnold-Schrauf, C.5    Hesse, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.