The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension

Cell

Volumn 169, Issue 4, 2017, Pages 693-707.e14

  Haarhuis, Judith H I ^a   van der Weide, Robin H ^a   Blomen, Vincent A ^a   Yáñez Cuna, J Omar ^a   Amendola, Mario ^a,d   van Ruiten, Marjon S ^a   Krijger, Peter H L ^b   Teunissen, Hans ^a   Medema, René H ^a   van Steensel, Bas ^a   Brummelkamp, Thijn R ^a,c   de Wit, Elzo ^a   Rowland, Benjamin D ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b HUBRECHT INSTITUTE   (Netherlands)

^c Department of Cell Biology and Genetics   (Netherlands)

^d GÉNÉTHON   (France)

Author keywords

chromatin looping; cohesin; CTCF; loop extrusion; MAU2; NIPBL; SCC2; SCC4; TADs; WAPL

Indexed keywords

COHESIN; DNA; ACYLTRANSFERASE; CARRIER PROTEIN; CCCTC-BINDING FACTOR; CELL CYCLE PROTEIN; CHROMATIN; FATTY ACID ELONGASES; MULTIPROTEIN COMPLEX; NONHISTONE PROTEIN; NUCLEAR PROTEIN; ONCOPROTEIN; REPRESSOR PROTEIN; SCC4 PROTEIN, HUMAN; WAPAL PROTEIN, HUMAN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL COMPARTMENTALIZATION; CELL CONTACT; CELL FUNCTION; CELL VIABILITY; CHROMATIN; CHROMOSOME; CHROMOSOME STRUCTURE; CYTOGENETICS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENE; GENE EDITING; GENE EXPRESSION; GENETIC REGULATION; HAPLOIDY; HUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; WAPL GENE; CELL NUCLEUS; METABOLISM;

ACETYLTRANSFERASES; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL NUCLEUS; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; GENE EDITING; HUMANS; MULTIPROTEIN COMPLEXES; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS;

EID: 85018753870     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.04.013     Document Type: Article

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