Macrophage-secreted TNFα and TGFβ1 influence migration speed and persistence of cancer cells in 3D tissue culture via independent pathways

Cancer Research

Volumn 77, Issue 2, 2017, Pages 279-290

  Li, Ran ^a   Hebert, Jess D ^b   Lee, Tara A ^a   Xing, Hao ^a   Boussommier Calleja, Alexandra ^a   Hynes, Richard O ^b   Lauffenburger, Douglas A ^a,b   Kamm, Roger D ^a  

^a Massachusetts Institute of Technology   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIX METALLOPROTEINASE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR; TGFB1 PROTEIN, HUMAN; TNF PROTEIN, HUMAN;

ARTICLE; BEHAVIOR; BONE MARROW DERIVED MACROPHAGE; CANCER CELL; CELL MIGRATION; CELL MIGRATION ASSAY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MACROPHAGE; METASTASIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SOLID MALIGNANT NEOPLASM; TISSUE CULTURE; TUMOR MICROENVIRONMENT; WESTERN BLOTTING; CELL MOTION; METABOLISM; MICROFLUIDIC ANALYSIS; PATHOLOGY; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE; TUMOR CELL LINE; TUMOR INVASION;

BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; HUMANS; MACROPHAGES; MATRIX METALLOPROTEINASES; MICROFLUIDIC ANALYTICAL TECHNIQUES; NEOPLASM INVASIVENESS; REAL-TIME POLYMERASE CHAIN REACTION; TISSUE CULTURE TECHNIQUES; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85018633869     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-16-0442     Document Type: Article

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