Immunocytochemical localization of latent transforming growth factor- β1 activation by stimulated macrophages

Journal of Cellular Physiology

Volumn 178, Issue 3, 1999, Pages 275-283

  Chong, Hyonkyong ^a   Vodovotz, Yoram ^b,c   Cox, George W ^b,d   Barcellos Hoff, M H ^a,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c WASHINGTON HOSPITAL CENTER   (United States)

^d UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^e LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; PROTEINASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CANCER CELL CULTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; KIDNEY SARCOMA; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY MECHANISM;

NASA DISCIPLINE RADIATION HEALTH; NON-NASA CENTER;

ANIMALS; CELL LINE; HUMANS; IMMUNOHISTOCHEMISTRY; LUCIFERASES; MACROPHAGES; MICE; MINK; RECOMBINANT PROTEINS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 0032931521     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199903)178:3<275::AID-JCP1>3.0.CO;2-Q     Document Type: Article

References (45)

1. Abe M, Harpel JG, Metz CN, Nunes I, Loskutoff DJ, Rifkin DB. 1994. An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem 216:276-284.
2. Antonelli-Orlidge A, Saunders KB, Smith SR, D'Amore PA. 1989. An activated form of transforming growth factor β is produced by cocultures of endothelial cells and pericytes. Proc Natl Acad Sci USA 86:4544-4548.
3. Arrick BA, Lopez AR, Elfman F, Ebner R, Damsky CH, Derynck R. 1992. Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth β 1. J Cell Biol 118:715-726.
4. Assoian RK, Fleurdelys BE, Stevens HC, Miller PJ, Madtes DK, Raines EW, Ross R, Sporn MB. 1987. Expression and secretion of type β transforming growth factor by activated human macrophages. Proc Natl Acad Sci USA 84:6020-6024.
5. Barcellos-Hoff MH. 1996. Latency and activation in the regulation of TGF-β. J Mam Gland Biol Neoplasia 3:353-363.
6. Barcellos-Hoff MH, Dix TA. 1996. Redox-mediated activation of latent transforming growth factor-β 1. Mol Endocrinol 10:1077-1083.
7. Barcellos-Hoff MH, Derynck R, Tsang ML-S, Weatherbee JA. 1994. Transforming growth factor-β activation in irradiated murine mammary gland. J Clin Invest 93:892-899.
8. Barcellos-Hoff MH, Ehrhart EJ, Kalia M, Jirtle R, Flanders K, Tsang ML-S. 1995. Immunohistochemical detection of active TGF-β in situ using engineered tissue. Am J Pathol 147:1228-1237.
9. Brown PD, Wakefield LM, Levinson AD, Sporn MB. 1990. Physiochemical activation of recombinant latent transforming growth factor-beta's 1, 2, and 3. Growth Factors 3:35-43.
10. Brunner AM, Marquardt H, Malacko AR, Lioubin MN, Purchio AF. 1989. Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor-β 1 precursor. J Biol Chem 264:13660-13664.
11. Childs CB, Proper JA, Tucker RF, Moses HL. 1982. Serum contains a platelet derived transforming growth factor-β. Proc Natl Acad Sci U S A 79:5312-5316.
12. Coffey RJ, Sipes N, Bascom C, Graves-Deal R, Pennington C, Weissman B, Moses H. 1988. Growth modulation of mouse keratinocytes by transforming growth factors. Cancer Res 48:1596-1602.
13. Derynck R, Jarrett JA, Chen EY, Eaton DH, Bell JR, Assoian RK, Roberts AB, Sporn MB, Goeddel DV. 1985. Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells. Nature 316:701-705.
14. Ehrhart EJ, Carroll A, Segarini P, Tsang ML-S, Barcellos-Hoff MH. 1997. Latent transforming growth factor-β activation in situ: quantitative and functional evidence following low dose irradiation FASEB J 11:991-1002.
15. Fine A, Goldstein RH. 1987. The effect of transforming growth factor-β on cell proliferation and collagen formation by lung fibroblasts. J Biol Chem 262:3897-3902.
16. Flanders KC, Tompson NL, Cissel DS, Van Obberghen-Schilling E, Baker CC, Kass ME, Ellingsworth LR, Roberts AB, Sporn MB. 1989. Transforming growth factor-β1 Histochemical localization with antibodies to different epitopes. J Cell Biol 108:653-660.
17. Gentry LE, Nash BW. 1990. The pro domain of pre-pro-transforming growth factor β1 when independently expressed is a functional binding protein for the mature growth factor. Biochemistry 29: 6851-6857.
18. Gleizes PE, Munger JS, Nunes I, Harpel JG, Mazzieri R, Noguera I, Rifkin DB. 1997. TGF-beta latency: biological significance and mechanisms of activation. Stem Cells 15:190-197.
19. Kehrl JH. 1991. Transforming growth factor-beta: an important mediator of immunoregulation. Int J Cell Cloning 9:438-450.
20. Kleeff J, Korc M. 1998. Upregulation of transforming growth factor (TGF)-beta receptors by TGF-beta1 in COLO-357 cells. J Biol Chem 274:7495-7500.
21. Kojima K, Nara K, Rifkin D. 1993. Requirement for transglutaminase in the activation of latent transforming growth factor-β in bovine endothelial cells. J Cell Biol 121:439-448.
22. Koli KM, Ramsey TT, Ko Y, Dugger TC, Brattain MG, Arteaga CL. 1997. Blockade of transforming growth factor-beta signaling does not abrogate antiestrogen-induced growth inhibition of human breast carcinoma cells. J Biol Chem 272:8296-302.
23. Laiho M, Weis FMB, Massague J. 1990. Concomitant loss of transforming growth factor (TGF)-β receptor types I and II in TGF-β resistant cell mutants implicates both receptor types in signal transduction. J Biol Chem 265:18518-18524.
24. Lawrence DA. 1991. Identification and activation of latent transforming growth factor β. Methods Enzymol 198:327-336.
25. Leof EB, Proper JA, Goutin AS, Shipley GD, DiCorleto PE, Moses HL. 1986. Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity. Proc Natl Acad Sci USA 83:2453-2457.
26. Lopez-Casillas F, Wrana JL, Massague J. 1993. Betaglycan presents ligand to the TGF-β signaling receptor. Cell 73:1435-1444.
27. Lyons RM, Gentry LE, Purchio AF, Moses HL. 1990. Mechanism of activation of latent recombinant transforming growth factor β1 by plasmin. J Cell Biol 110:1361-1367.
28. Miyazono K, Heldin C-H. 1991. Latent forms of TGF-β: molecular structure and mechanisms of activation. In: Block GR, Marsh J, editors. Clinical applications of TGF-β. Ciba Foundation Symposium 157. Chichester: John Wiley. p 81-92.
29. Moses HL, Coffey RL Jr, Leof EB, Lyons RM, Keski-Oja J. 1987. Transforming growth factor β regulation of cell proliferation. J Cell Physiol Suppl 5:1-7.
30. Nathan C, Sporn M. 1991. Cytokines in context. J Cell Biol 113:981-986.
31. Nunes I, Shapiero RL, Rifkin DB. 1995. Characterization of latent TGF-β activation by murine peritoneal macrophages. J Immunol 155:1450-1459.
32. Odekon LE, Blasi F, Rifkin DB. 1994. Requirement for receptor-bound urokinase in plasmin-dependent cellular conversion of latent TGF-β to TGF-β. J Cell Physiol 158:398-407.
33. Okada F, Yamaguchi K, Ichihara A, Nakamura T. 1989. One of two subunits of masking protein in latent TGF-β is a part of pro-TGF-β. FEBS Lett 242:240-244.
34. Roberts AB, Sporn MB, Assoian RK, Smithe JM, Roche NS, Wakefield LM, Heine UI, Liotta LA, Falanga V, Kehrl JH, Fauci AS. 1986. Transforming growth factor type β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 83:4167-4171.
35. Salo T, Lyons JG, Rahemtulla F, Birkedal-Hansen H, Larjaval H. 1991. Transforming growth factor-β 1 up-regulates type IV collagenase expression in cultured human keratinocytes. J Biol Chem 266:11436-11441.
36. Sappino AP, Schurch W, Gabbiani G. 1990. Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations. Lab Invest 63:144-161.
37. Sato Y, Tsuboi R, Lyons R, Moses H, Rifkin DB. 1990. Characterization of the activation of latent TGF-β by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system. J Cell Biol 111:757-763.
38. Schultz-Cherry S, Murphy-Ullrich JE. 1993. Thrombospondin causes activation of latent transforming growth factor-β secreted by endothelial cells by a novel mechanism. J Cell Biol 122:923-932.
39. Sun L, Chen C. 1997. Expression of transforming growth factor beta type III receptor suppresses tumorigenicity of human breast cancer MDA-MB-231 cells. J Biol Chem 272:25367-25372.
40. Twardzik DR, Mikovits JA, Ranchalis JE, Purchio AF, Ellingsworth L, Ruscetti FW. 1990 γ-interferon-induced activation of latent transforming growth factor-β by human monocytes. Ann N Y Acad Sci 593:276-284.
41. Vodovotz Y. 1997. Control of nitric oxide production by transforming growth factor-β1: mechanistic insights and potential relevance to human disease. Nitric Oxide: Biol and Chem 1:3-17.
42. Vollberg TM, George MD, Jetten AM. 1991. Induction of extracellular matrix gene expression in normal human keratinocytes by transforming growth factor-β is altered by cellular differentiation. Exp Cell Res 193:93-100.
43. Wahl SM. 1994. Transforming growth factor-β: the good, the bad, and the ugly. J Exp Med 180:1587-1590.
44. Wakefield LM, Smith DM, Flanders KC, Sporn MB. 1988. Latent transforming growth factor-β from human platelets: a high molecular weight complex containing precursor sequences. J Biol Chem 263:7646-7654.
45. Westergren-Thorsson G, Sarnstrand B, Fransson L-A, Malmstrom A. 1990. TGF-β enhances the production of hyaluronan in human lung but not in skin fibroblasts. Exp Cell Res 186:192-195.