Integrative modelling of TIR domain-containing adaptor molecule inducing interferon-β (TRIF) provides insights into its autoinhibited state

Biology Direct

Volumn 12, Issue 1, 2017, Pages

  Mahita, Jarjapu ^a   Sowdhamini, Ramanathan ^a  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

Autoinhibition; Docking; Molecular dynamics simulations; Mutual information; Residue network analysis; TRIF

Indexed keywords

SIGNAL TRANSDUCING ADAPTOR PROTEIN; TICAM1 PROTEIN, HUMAN; TICAM2 PROTEIN, HUMAN; TLR3 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 3; VESICULAR TRANSPORT ADAPTOR PROTEIN;

BINDING SITE; CHEMISTRY; HYDROGEN BOND; INNATE IMMUNITY; METABOLISM; MOLECULAR DYNAMICS; PHYSIOLOGY; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; BINDING SITES; HYDROGEN BONDING; IMMUNITY, INNATE; MOLECULAR DYNAMICS SIMULATION; PROTEIN DOMAINS; STRUCTURE-ACTIVITY RELATIONSHIP; TOLL-LIKE RECEPTOR 3;

EID: 85018501547     PISSN: None     EISSN: 17456150     Source Type: Journal    
DOI: 10.1186/s13062-017-0179-0     Document Type: Article

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