An alanine-to-proline mutation in the BB-loop of TLR3 Toll/IL-1R domain switches signalling adaptor specificity from TRIF to MyD88

Journal of Immunology

Volumn 191, Issue 12, 2013, Pages 6101-6109

  Verstak, Brett ^a   Arnot, Christopher J ^a   Gay, Nicholas J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; BETA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 1 RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; PROLINE; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; GENE ACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; WILD TYPE;

EID: 84890369104     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1300849     Document Type: Article

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