Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases

Journal of Molecular Biology

Volumn 429, Issue 10, 2017, Pages 1554-1569

  Faille, Alexandre ^a   Gavalda, Sabine ^a   Slama, Nawel ^a   Lherbet, Christian ^b   Maveyraud, Laurent ^a   Guillet, Valérie ^a   Laval, Françoise ^a   Quémard, Annaïk ^a   Mourey, Lionel ^a   Pedelacq, Jean Denis ^a  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^b UPS   (France)

Author keywords

dehydratase; metabolizable ligand; Mycobacterium tuberculosis; polyketide synthase; X ray structure

Indexed keywords

ENOYL COENZYME A HYDRATASE; HYDROLYASE; HYDROXYACYL DEHYDRATASE; POLYKETIDE SYNTHASE; POLYKETIDE SYNTHASE PPSC; SYNTHETASE; UNCLASSIFIED DRUG; ACYL COENZYME A; PROTEIN BINDING;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; HYDRATION; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DOMAIN; X RAY CRYSTALLOGRAPHY; CHEMISTRY; ENZYMOLOGY; METABOLISM; MOLECULAR MODEL; MYCOBACTERIUM TUBERCULOSIS; PROTEIN CONFORMATION;

ACYL COENZYME A; CRYSTALLOGRAPHY, X-RAY; HYDRO-LYASES; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; POLYKETIDE SYNTHASES; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 85018457462     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2017.03.026     Document Type: Article

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