Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway

Structure

Volumn 18, Issue 1, 2010, Pages 94-105

  Akey, David L ^a   Razelun, Jamie R ^a   Tehranisa, Jason ^b   Sherman, David H ^b   Gerwick, William H ^c   Smith, Janet L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

PROTEINS

Indexed keywords

CURACIN A; DIMER; FATTY ACID SYNTHASE; HYDROLYASE; HYDROXYL GROUP; MONOMER; POLYKETIDE; POLYKETIDE SYNTHASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; BIOSYNTHESIS; CATALYSIS; CHIRALITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SPECIES DIFFERENCE;

AMINO ACID SEQUENCE; BIOCATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYCLOPROPANES; HYDRO-LYASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POLYKETIDE SYNTHASES; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; THIAZOLES;

MAMMALIA;

EID: 73449104701     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2009.10.018     Document Type: Article

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