Phthiocerol dimycocerosates of M. tuberculosis participate in macrophage invasion by inducing changes in the organization of plasma membrane lipids

PLoS Pathogens

Volumn 5, Issue 2, 2009, Pages

  Astarie Dequeker, Catherine ^a,b   Le Guyader, Laurent ^a,b   Malaga, Wladimir ^a,b   Seaphanh, Fam Ky ^a,b   Chalut, Christian ^a,b   Lopez, André ^a,b   Guilhot, Christophe ^a,b  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE LIPID; PHTHIOCEROL DIMYCOCEROSATE; UNCLASSIFIED DRUG; VIRULENCE FACTOR; CHOLESTEROL; LIPID;

ACIDIFICATION; ARTICLE; BIOSYNTHESIS; CELL INVASION; CELL MEMBRANE FLUIDITY; CONTROLLED STUDY; GENE DELETION; HUMAN; HUMAN CELL; LIPID BLOOD LEVEL; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; PHAGOSOME; CELL MEMBRANE; GENE INACTIVATION; GENETICS; LIGHT; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PH; PHYSIOLOGY; RADIATION SCATTERING;

BACILLI (CLASS); MYCOBACTERIUM TUBERCULOSIS;

CELL MEMBRANE; CHOLESTEROL; GENE KNOCKOUT TECHNIQUES; HUMANS; HYDROGEN-ION CONCENTRATION; LIGHT; LIPIDS; MACROPHAGES; MEMBRANE LIPIDS; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; PHAGOSOMES; SCATTERING, RADIATION; VIRULENCE FACTORS;

EID: 61449089528     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000289     Document Type: Article

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