Stereoselectivity of Isolated Dehydratase Domains of the Borrelidin Polyketide Synthase: Implications for cis Double Bond Formation

ChemBioChem

Volumn 12, Issue 7, 2011, Pages 1011-1014

  Vergnolle, Olivia ^a,b   Hahn, Frank ^a   Baerga Ortiz, Abel ^a,c   Leadlay, Peter F ^a   Andexer, Jennifer N ^a,d  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b CITY UNIVERSITY OF NEW YORK   (United States)

^c UNIVERSITY OF PUERTO RICO SCHOOL OF MEDICINE   (Puerto Rico)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Borrelidin; Dehydration; Double bonds; Enzyme catalysis; Polyketides

Indexed keywords

BORRELIDIN; HYDROLYASE; POLYKETIDE SYNTHASE;

ARTICLE; COVALENT BOND; CYCLIZATION; DRUG SYNTHESIS; ENZYME CONFORMATION; ENZYME ISOLATION; HYDRATION; ISOMERIZATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; X RAY DIFFRACTION;

FATTY ALCOHOLS; HYDRO-LYASES; POLYKETIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; STEREOISOMERISM;

EID: 79955015997     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201100011     Document Type: Article

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