Postnatal hyperoxia exposure durably impairs right ventricular function and mitochondrial biogenesis

American Journal of Respiratory Cell and Molecular Biology

Volumn 56, Issue 5, 2017, Pages 609-619

  Goss, Kara N ^a,b   Kumari, Santosh ^a,b   Tetri, Laura H ^b,c   Barton, Greg ^b,c   Braun, Rudolf K ^b,c   Hacker, Timothy A ^d   Eldridge, Marlowe W ^b,c  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Rankin Laboratory of Pulmonary Medicine   (United States)

^c Division of Pediatric Critical Care   (United States)

^d University of Wisconsin Cardiovascular Research Center   (United States)

Author keywords

Mitochondrial biogenesis; Prematurity; Pulmonary hypertension

Indexed keywords

MITOCHONDRIAL DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CARDIOPULMONARY HEMODYNAMICS; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; ECHOCARDIOGRAPHY; FEMALE; HEART INDEX; HEART RIGHT VENTRICLE EJECTION FRACTION; HEART RIGHT VENTRICLE FUNCTION; HEART RIGHT VENTRICLE HYPERTROPHY; HYPEROXIA; MALE; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL DNA DISORDER; NONHUMAN; PREMATURITY; RAT; SYSTOLIC BLOOD PRESSURE; WESTERN BLOTTING; AGING; ANIMAL; AUTOPHAGY; BODY WEIGHT; CARDIAC MUSCLE; COMPLICATION; DIAGNOSTIC IMAGING; FIBROSIS; GENE EXPRESSION PROFILING; GENETICS; HEMODYNAMICS; HYPERTROPHY, RIGHT VENTRICULAR; METABOLISM; NEWBORN; ORGAN SIZE; ORGANELLE BIOGENESIS; PATHOLOGY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

AGING; ANIMALS; ANIMALS, NEWBORN; AUTOPHAGY; BODY WEIGHT; DNA DAMAGE; DNA, MITOCHONDRIAL; FEMALE; FIBROSIS; GENE EXPRESSION PROFILING; HEMODYNAMICS; HYPEROXIA; HYPERTROPHY, RIGHT VENTRICULAR; MALE; MYOCARDIUM; MYOCYTES, CARDIAC; ORGAN SIZE; ORGANELLE BIOGENESIS; RATS, SPRAGUE-DAWLEY; VENTRICULAR FUNCTION, RIGHT;

EID: 85018384136     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2016-0256OC     Document Type: Article

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